Clinical trials: Physical Frailty
Heart Failure
Frailty Score Assessment for Elderly Patients Undergoing Cardiac Resynchronization Therapy
Background: The cardiac resynchronization therapy (CRT) has been shown to improve symptoms and outcome of patients with congestive heart failure (HF), and depressed left ventricular ejection fraction (LVEF < 35 %).
- Trial name
- FRAILTY (NCT02369419)
- Testing
- Frailty
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Nutritional Status, Muscle Thickness of the Quadriceps Femoris
Ultrasound, Nutritional Status, and Outcomes in Surgical ICU
Ultrasound Indicators of Nutritional Status and Treatment Outcomes in Surgical Patients in the Intensive Care Unit
- Conditions
- Nutritional Status, Muscle Thickness of the Quadriceps Femoris, Frailty
- Trial name
- NCT07475767
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Aging, Cellular Senescence
BIOANCIENT_EX: Effects of a Physical Exercise Program in Centenarians of the BIOANCIENT Cohort: A Randomized Clinical Trial.
This study aims to evaluate the effects of a home intervention of individualized multicomponent physical exercise program (including strength, balance, flexibility, and mobility training) on functional health, physical capacity…
- Conditions
- Aging, Cellular Senescence, Biomarkers / Blood, Exercise
- Trial name
- BIOANCIENT_EX (NCT07723339)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundacion Miguel Servet
Older Adults
The Effectiveness of Health Promotion Programs on the Pre-frail Individuals
This pilot study aimed to examine the efficacy of a home-based multicomponent exercise training program in older community- dwellers during to the Coronavirus Disease 2019.
- Trial name
- NCT05476471
- Testing
- multicomponent exercise training program
- Where
- Taiwan
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Shu-Hung Chang
Myeloma, Multiple, Paraproteinemias
Comprehensive Frailty Assessment
The purpose of this research study is to describe a patients' fitness before and after treatment (whether that treatment be chemotherapy or a transplant). Fitness is a way of measuring a patient's current quality of health.
- Conditions
- Myeloma, Multiple, Paraproteinemias, Hematologic Neoplasms
- Trial name
- NCT02033928
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Hemodialysis Complication, Nutritional Deficiency
Frailty Intervention Trial in End-Stage Patients on Dialysis
The proposed investigation for this study aims to; 1) understand the prevalence and outcomes associated with frailty among haemodialysis patients; 2) ascertain the best frailty assessment tool for haemodialysis patients, and; 3)…
- Conditions
- Hemodialysis Complication, Nutritional Deficiency, Physical Activity
- Trial name
- FITNESS (NCT03071107)
- Testing
- Multi-disciplinary intervention
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Adnan Sharif
Frail Elderly Syndrome, Physical Activity
Frailty Prevention in Elders From Reunion Island
In Reunion Island, people encounter environmental and social conditions leading to premature ageing and subsequent frailty. Social welfare has developped exercise programs to promote physical activity especially for elderly with…
- Trial name
- 5P-PILOTE (NCT03271112)
- Testing
- Exercise program
- Where
- Reunion
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Frailty, Comprehensive Geriatric Assessment
Integrated Care with GP Participation for Older Persons in the Ambulatory Care Hub: a Prospective Cohort Study.
Comprehensive Geriatric Assessment (CGA) demonstrates positive outcomes amoung community-dwelling older people living with frailty.
- Trial name
- NCT05527223
- Where
- Ireland
- Volunteers
- 303 people
- Sponsor
- University of Limerick
Multiple Myeloma
Integrating Touchscreen-based Geriatric Assessment and Frailty Screening for Adults With Multiple Myeloma
The overarching objective of this study is to evaluate the feasibility, usability, and acceptability of an abbreviated, tablet-based geriatric assessment in a population of older adults with multiple myeloma.
- Trial name
- NCT03068637
- Testing
- Carevive CPS
- Where
- 2 sites in United States
- Volunteers
- 165 people
- Sponsor
- Carevive Systems, Inc.
Frailty, Fall Risk, Fall Prevention
Physical Function and Fall Risk in Older Adults in the Lalín Frailty Prevention Program
This prospective observational study will describe changes in physical function and fall risk among adults aged 70 years or older who participate in the routine Frailty and Falls Prevention Program at the Centro Integral de Saúde…
- Trial name
- FRAIL-Lalin (NCT07848802)
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- University of Vigo
Frailty, Aging
Comprehensive Geriatric Assessment in Primary Care
This study evaluates the feasibility and acceptability of implementing the electronic Comprehensive Geriatric Assessment (eCGA) in primary care for adults aged 65 years and older.
- Conditions
- Frailty, Aging, Geriatric Syndromes, Mobility Limitation
- Trial name
- PC-CGA (NCT07341061)
- Testing
- Personalized Approach for Healthy Aging (PAHA)
- Volunteers
- 120 people
- Sponsor
- Nova Scotia Health Authority
Kidney Disease, Kidney Failure
Older Kidney Patient Optimisation Pretransplant
The goal of this clinical trial is to learn if a kidney transplant-specific comprehensive geriatric assessment (KT-CGA) can improve the way older adults are assessed for kidney transplantation.
- Conditions
- Kidney Disease, Kidney Failure, Frailty, Cognitive Impairment
- Trial name
- OK-POP (NCT07419945)
- Testing
- Kidney transplant-specific comprehensive geriatric assessment
- Volunteers
- 50 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Frailty, Sarcopenia
Development of Continuous Assessment of Frailty and Muscle Quality in Older Subjects: ECOFRAIL Protocol
We are conducting a study in different centers in Spain in elderly people, in order to assess the effectiveness of a physical exercise intervention program in people in a situation of frailty.
- Conditions
- Frailty, Sarcopenia, Ultrasonography, Exercise
- Trial name
- ECOFRAIL (NCT05294757)
- Testing
- Physical exercise
- Where
- 3 sites in Spain
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Elderly
A Individualized Physical Function Improvement Program for Frailty Elderly Using Goal Attainment Scaling (GAS) as Evaluation Method: Protocol for a Randomized Controlled Trial
Frailty refers to the age-related decline in physiological functions，that is associated with adverse outcomes. Frailty is a dynamic reversible state, that requires a comprehensive individualized management.
- Trial name
- NCT06919575
- Testing
- Multicomponent frailty intervention
- Volunteers
- 160 people
- Sponsor
- Beijing Chao Yang Hospital
Gynecologic Cancer, Frailty
Cognitive and Physical Frailty as Predictors of Decision Satisfaction in Geriatric Gynecologic Oncology
This prospective observational study aims to evaluate the association between preoperative cognitive function, measured by the Montreal Cognitive Assessment (MoCA), and physical frailty, assessed using the Clinical Frailty Scale…
- Conditions
- Gynecologic Cancer, Frailty, Cognitive Impairment, Geriatric Oncology
- Trial name
- GYNCOGFRAIL (NCT07085000)
- Testing
- No Intervention - Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Izmir City Hospital
Frailty in Older Adults
Chair-bound Exergaming in Pre-frail/ Frail Older Adults in Nursing Home
This pilot randomized controlled trial is designed to investigate the effectiveness of chair-bound exergaming on improving physical and cognitive function in pre-frail/ frail nursing home residents
- Trial name
- NCT06849557
- Testing
- Exergaming
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Hong Kong Metropolitan University
Frailty, Cardiac Surgery
SAGE-Heart : Senior Assessment fraGility and Post-opErative QALYs 1 Year After Emergency HEART Surgery for Patients Aged 75 and Older
The hypothesis is that the preoperative Clinical Frailty Score (CFS) is a predictive factor for a loss in quality-adjusted life years (QALYs) one year after emergency cardiac surgery under cardiopulmonary bypass (CPB) in patients…
- Conditions
- Frailty, Cardiac Surgery, QALYs
- Trial name
- SAGE-Heart (NCT07677319)
- Testing
- Phone Calls
- Where
- France
- Volunteers
- 265 people
- Sponsor
- University Hospital, Bordeaux
Frailty, Surgery--Complications
The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With Frailty
This study evaluates whether participating in a home-based exercise program leads to lower levels of complication rates and patient-reported disability after surgery.
- Conditions
- Frailty, Surgery--Complications, Disability Physical
- Trial name
- NCT04221295
- Testing
- Exercise Group
- Where
- Canada
- Volunteers
- 850 people
- Sponsor
- Ottawa Hospital Research Institute
Frailty, Aged
Triage Assessment and NEWS-score as Risk Predictor in Older Frailty Adults in the ED
Emergency Department Triage Systems have not been shown to sufficiently recognize frail elderly patients in need of urgent assessment and care.
- Conditions
- Frailty, Aged, Triage
- Trial name
- NCT03783234
- Where
- Finland
- Volunteers
- 1,711 people
- Sponsor
- Helsinki University Central Hospital