Clinical trials: Physical Frailty
Bladder Cancer
Comprehensive Geriatric Assessment for Perioperative Optimization in Cystectomy
Patients with muscle-invasive bladder cancer are often older and multimorbid, thus in an increased risk of perioperative mortality and morbidity in relation to radical cystectomy (RC).
- Trial name
- COMPETENCE (NCT05679557)
- Testing
- Perioperative geriatric assessment and intervention
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Aarhus University Hospital
Fraility, Critical Illness
Investigation of the Relationship Between Nutritional Status Assessment and Frailty in Critical Care Patients
This study aims to understand the effects of these two parameters on clinical outcomes by examining the relationship between NUTRIC and CONUT scores in intensive care patients.
- Trial name
- NCT07143084
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara Training and Research Hospital
Chronic Conditions, Multiple, Old Age; Debility
Brief Physical Activity Intervention for Older People With Multimorbidity
Physical activity is an important determinant of health and well-being in older people. However, many older people do not achieve recommended physical activity levels and increasing older people's physical activity is…
- Conditions
- Chronic Conditions, Multiple, Old Age; Debility, Physical Inactivity
- Trial name
- NCT05287932
- Testing
- Brief physical activity intervention
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Northumbria University
Aging, Frailty
Renal Ageing-sarcopenia Network
Frailty is a syndrome in which the accumulation of small, individually insignificant deficits leads to heightened vulnerability to adverse events and predisposes to potential catastrophic decompensation.
- Conditions
- Aging, Frailty, Hypertension, CKD
- Trial name
- NCT04630132
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Social Isolation, Depression
Discharge Functional Status and Rehospitalization in the Elderly
The DC PROMIS Study (also known as the Discharge Patient Reported Outcomes Measurement Information System Study) is a study to see the effect of patients' social, physical and mental function on their health after hospital…
- Conditions
- Social Isolation, Depression, Anxiety, Debility
- Trial name
- DC PROMIS (NCT02041585)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Comprehensive Assessment of Frailty
Frailty In Cardiac Surgery Copenhagen Study
Background: Over the past decades there have been seen an increase in life expectancy in Denmark. One of the consequences is that the patients who need heart surgery have a higher average age and some of these patients have a…
- Trial name
- FICS (NCT02992587)
- Testing
- CAF, Comprehensive assessment of frailty
- Volunteers
- 600 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Atrial Fibrillation
The European Registry of Older Subjects With Atrial Fibrillation (EUROSAF)
Preliminary data suggest that: 1. a different risk of mortality, as assessed by the Multidimensional Prognostic Indices (MPI), may influence the anticoagulant prescription in older subjects with Atrial Fibrillation (AF); 2.
- Trial name
- EUROSAF (NCT02973984)
- Where
- Italy
- Volunteers
- 3,000 people
- Sponsor
- Alberto Pilotto
Gastrointestinal Cancers, Frailty
Longitudinal Geriatric Vulnerability, Chemotherapy Toxicity, and Functional Outcomes in Older Adults With Gastrointestinal Cancer
Older adults with gastrointestinal cancers may be more likely to experience side effects from chemotherapy and difficulties with everyday activities. These problems are not always explained by age alone.
- Conditions
- Gastrointestinal Cancers, Frailty, Sarcopenia in Elderly, Malnutrition Elderly
- Trial name
- VITAL-GI (NCT07184047)
- Testing
- Standard-of-Care Systemic Chemotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Ankara Etlik City Hospital
Elderly
Activity Monitoring in Frail Elderly Patients
The purpose of this stuydy is to assess the bias and repeatability of the DynaPort MicroMod in measuring movement / physical activity in frail elderly.
- Trial name
- NCT02089516
- Where
- 2 sites in Netherlands
- Volunteers
- 18 people
- Sponsor
- Medical Research Foundation, The Netherlands
Frailty, Quality of Life
Impact of a Personalized Multicomponent Exercise Program in Real Conditions Among Older Adults With HIV
Longitudinal prospective multicenter study with intervention and control groups and a two-year follow up. Participants will include 40 sedentary adults 50 years old or older with HIV infection and 20 sedentary adults 50 years old…
- Conditions
- Frailty, Quality of Life, Physical Inactivity, Body Composition
- Trial name
- MOVIhNG (NCT05435521)
- Testing
- Personalized multicomponent exercise program (strength, resistance, balance, and flexibility) (PMEP), Body composition, Musculoskeletal and visceral Ultrasound
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Ramon y Cajal
Frailty, Older People
A Service-Learning Program for Comprehensive Geriatric Assessment and Health Promotion in Older Adults
The GEROS Project aims to develop and implement a Service-Learning (S-L) program that integrates Comprehensive Geriatric Assessment (CGA) and health promotion, for students at the Faculty of Health Sciences and Welfare at the…
- Conditions
- Frailty, Older People, Comprehensive Geriatric Assessment, Health Promotion
- Trial name
- GEROS (NCT06890325)
- Testing
- Comprehensive Geriatric Assessment (CGA), Health education
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Frailty, Chronic Pain
Effectiveness of a Physical Activity Intervention for Pre-frail Older Adults With Chronic Pain.
The purpose of this investigation is to evaluate the effectiveness of a multicomponent structured physical exercise program for adults aged 65 years or more, classified as pre-frail and with chronic pain to improve the Perceived…
- Conditions
- Frailty, Chronic Pain, Old Age; Debility
- Trial name
- NCT04045535
- Testing
- Physical Activity Program, Usual care
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Frail Elderly
Synergy of Exercise and Nutrition in Preventing and Treating Frailty
The goal of this clinical study is to learn if combining a nutritional supplement with a multicomponent exercise program can help prevent and treat frailty in community dwelling older adults.
- Trial name
- ROBUSTNES (NCT06975540)
- Testing
- Multidomain physical exercise
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Frailty, Sarcopenia
PRISMA 7 and SARC-F in Predicting Emergency Department Readmission and Mortality
Frailty scores can predict hospitalization and other related adversities. Thus, the frailty status determination is useful in clinical decisions regarding elderly patients.
- Conditions
- Frailty, Sarcopenia, Morality
- Trial name
- NCT06525038
- Testing
- All groups were observed for clinical end-points described in the study protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Firat University
Aging
Preliminary Testing of Cafe Move for Primary Prevention of Physical Frailty
This project explores a novel means of health promotion and prevention of age-related physical frailty, which is designed to overcome barriers to access and promote autonomy in managing physical health.
- Trial name
- NCT05720507
- Testing
- Cafe Move
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Montana
Chronic Thromboembolic Pulmonary Hypertension, Physical Disability
Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients
The goal of this observational and prospective study is to investigate changes in physical performance, lung function, respiratory and peripheral muscle strength in patients during the postoperative period following pulmonary…
- Conditions
- Chronic Thromboembolic Pulmonary Hypertension, Physical Disability, Fragility
- Trial name
- NCT06286891
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Syndrome
Comprehensive Validation of Frailty Assessment Tools in Older Adults in Different Clinical and Social Settings
There is a proved strong evidence of the usefulness of frailty as a predictive factor of relevant and desired outcomes in populations of older adults.
- Trial name
- FRAILTOOLS (NCT02637518)
- Testing
- Assessment of frailty tools in elderly people
- Where
- Spain
- Volunteers
- 1,940 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Getafe
Cirrhosis, Liver, Liver Transplant Surgery
Online Prehabilitation for Patients Awaiting Liver Transplantation
Physical frailty is common in patients awaiting liver transplantation and has been associated with poor health outcomes. There is promising data from small studies showing that behavioural, nutrition, exercise therapy…
- Conditions
- Cirrhosis, Liver, Liver Transplant Surgery, Liver Disease
- Trial name
- OPAL (NCT05899231)
- Testing
- Prehabilitation Programming
- Where
- 6 sites in Canada
- Volunteers
- 177 people
- Sponsor
- University of Alberta
Frailty Syndrome
The Effectiveness of Training Using Exergaming on Selected Physical and Psychological Parameters in a Population of Patients Over the Age of 65 Belonging to Specific Subgroups of the Frailty Syndrome
This study aims to evaluate the effects of a six-week exergaming-based training program on physical and psychological parameters in individuals aged 65 and older diagnosed with frailty or pre-frailty.
- Trial name
- FREX (NCT07036224)
- Testing
- Exergaming Training using Kinect sensor device
- Where
- Poland
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University