Clinical trials: Physical Frailty
Inpatients, Frail
Effect of Using a Reminder to Encourage Patients to be Active During Their Hospital Stay.
Around 30% of patients aged 65 and over experience functional decline due to hospitalization. Physical inactivity, often without medical justification, is common during hospital stays.This immobility leads to loss of autonomy…
- Trial name
- REMOTIVE (NCT07492745)
- Testing
- Vibrating reminder, Control group
- Where
- 4 sites in Belgium, France
- Volunteers
- 204 people
- Sponsor
- Groupe Hospitalier du Havre
Colon Cancer, Frailty
Optimised Post-discharge Care in Older Patients After Surgery for Colon Cancer (ERAS 3.0)
The purpose of the study is to investigate whether an extended program (ERAS 3.0) initiated hospital discharge, can improve recovery in elderly, frail patients who have undergone surgery for colon cancer.
- Trial name
- NCT06802991
- Testing
- ERAS 3.0 (Enhanced Recovery After Surgery)
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital at Herlev
End Stage Renal Disease, Hemodialysis Complication
The Effect of Home-Based Tele-Exercise on Dialysis Patients
The objective of the trial is to assess key areas of uncertainty regarding the use of synchronous home-based tele-exercise in future practice and research, including issues relating to feasibility, safety and potential for…
- Trial name
- NCT06313892
- Testing
- Home-based Exercise
- Where
- Iran
- Volunteers
- 26 people
- Sponsor
- Pardis Specialized Wellness Institute
Frailty at Older Adults, Primary Care
Implementation of a Clinical Decision Support System in Primary Care for the Screening and Assessment of Frailty in Patients Aged 65 and Over
This observational study aims to evaluate the real-life use of a digital tool (Fragiclic) by general practitioners (GPs) and nurses to screen and assess frailty in adults aged 65 and over.
- Conditions
- Frailty at Older Adults, Primary Care, Geriatric Assessment, Implementation Research
- Trial name
- FRAGICLIC (NCT07570628)
- Where
- France
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- CNGE Conseil
Frailty at Older Adults
Motivational Support for an Autonomous Exercise Program for Healthy Aging
An effective implementation of an exercise programme such as VIVIFRAIL, in an unsupervised mode, requires a careful consideration of the patient's motivational traits and state, and the adaptation of the interventions to the…
- Trial name
- MOTIVA (NCT07447453)
- Testing
- MOTIVA ecosystem
- Where
- 2 sites in Spain
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Getafe
COPD, Diabetes
Effectiveness of Physical Exercise of Patients With Chronic Non-communicable Disease
According to the Pan American Health Organization (PAHO), chronic, non-communicable diseases (NCDs) are the main cause of death and disability in the world.
- Conditions
- COPD, Diabetes, Physical Inactivity, Frailty
- Trial name
- NCT06476015
- Testing
- Therapeutic exercise
- Where
- Colombia
- Volunteers
- 300 people
- Sponsor
- Fundacion Universitaria Maria Cano
Heart Failure
AI-Based Conversational Social Support for Older Adults With Heart Failure
This three-year study aims to investigate gender differences in social frailty and evaluate the effects of an artificial intelligence (AI)-based conversational social-support intervention among older adults with chronic heart…
- Trial name
- NCT07862933
- Testing
- AI-Based Conversational Social Support, Community Social Participation
- Where
- 2 sites in Taiwan
- Volunteers
- 174 people
- Sponsor
- Chang Gung University of Science and Technology
HIV
Feasibility of an Exercise Intervention
The overall purpose of this research is to evaluate the effect of a home-based exercise program on physical function and to improve the health and quality of life for the HIV-infected older adult community.
- Trial name
- MESH (NCT01984060)
- Testing
- HOME-EX
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Rochester
Quality of Life, Aortic Valve Stenosis
Frailty and Cognitive Function Assessment of TAVI Patients
Aortic stenosis (AS) is the most common valve disease among the adult population, in the majority of the cases it only requires treatment in advanced age.
- Conditions
- Quality of Life, Aortic Valve Stenosis, Heart Valve Disease
- Trial name
- NCT02650388
- Testing
- Cognitive fuction, quality of life
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Hungarian Institute of Cardiology
Rehabilitation, Training
The Effect of Modified Stepping Trainings in Frailty Elderly With Physical Performance- a Prospective Randomized Controlled Trial
This single-blind, randomized controlled trial compared the effects of modifiled stepping exercise training on flat step and unstable step on the functional outcomes in community-dwelling older adults.
- Conditions
- Rehabilitation, Training, Respiratory Muscle Strength
- Trial name
- NCT06505083
- Testing
- modified stepping trainings
- Where
- Thailand
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chonticha Kaewjoho
End-Stage Renal Disease, Hemodialysis Complication
The Effect of Home-based Exercise on Postural Abnormalities
This study evaluates the effects of synchronous home-based tele-exercise on postural abnormalities (FHP and hyper-kyphosis) in dialysis patients.
- Trial name
- NCT06877962
- Testing
- Home-based Tele Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
Cancer, Geriatric Syndrome
Risk-Based Geriatric Assessment-Driven Management in Older Patients Starting Chemotherapy
Older patients with cancer are at increased risk of severe chemotherapy-related toxicities due to comorbidities, functional impairments, and geriatric syndromes.
- Conditions
- Cancer, Geriatric Syndrome, Frailty, Chemotherapy Toxicity
- Trial name
- NCT07485634
- Testing
- Geriatric Assessment-Driven Management Algorithm (GA-MA)
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- The University of Hong Kong
Cardiac Surgery, Rehabilitation
Physical Performance Testing and Frailty in Prediction of Early Postoperative Course After Cardiac Surgery
Standard risk prediction models in cardiac surgery (such as EuroSCORE II or STS score) are designed to analyze solely the risk of short-term postoperative mortality.
- Conditions
- Cardiac Surgery, Rehabilitation, Frailty, Physical Performance
- Trial name
- Cardiostep (NCT05166863)
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Jan Gofus, MD, PhD
Preventing Age-Related Muscle Loss: the Role of Exercise in Improving Strength, Function, and Well-being
Muscle Aging Evaluation
This study aims to assess the effects of physical activity in counteracting muscle aging. The increasing life expectancy worldwide has led to a rise in age-related muscle decline, which negatively impacts strength, function, and…
- Trial name
- NCT06845748
- Testing
- Physical activity Group
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Milan
Frailty
Feasibility and Acceptability of the Clinical Frailty Scale in a Swedish Emergency Department Setting
The purpose of this study is to evaluate the feasibility and acceptability of the Clinical Frailty Scale (CFS). The scale can potentially be adopted for daily use in the Emergency Department (ED) and have been evaluated with…
- Trial name
- NCT04931472
- Where
- Sweden
- Volunteers
- 229 people
- Sponsor
- University Hospital, Linkoeping
Cancer Survivors
Virtual Exercise Training and Its Impact on Bone Compartments in Adult Survivors of Childhood Cancer
Childhood cancer is a rare disease but a significant cause of death in children and adolescents. The incidence of childhood cancer is 1case per 300 cases of adult cancer, but surviving to it has important sequels.
- Trial name
- 3D-BONE (NCT07022262)
- Testing
- Progressive resistance training plus impact loading
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Universidad de Granada
Physical Frailty, Hip Fracture
Exercise and Testosterone Therapy in Elderly Men With Physical Frailty
The primary aim of this study is to determine, in hypogonadal older men with physical frailty, whether exercise training combined with testosterone replacement therapy can improve skeletal muscle strength, and lean mass, to a…
- Conditions
- Physical Frailty, Hip Fracture, Elective Hip Replacement, Hypogonadism
- Trial name
- NCT00345969
- Testing
- Transdermal Testosterone gel (1%), Supervised exercise training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Washington University School of Medicine
Old Age; Debility
Impact of a Physical Exercise Program in a Rural Area
With this work we want to assess whether there are differences in the amount of physical activity per week, measured by accelerometry in 3 groups of subjects, where one group (G1) has been carrying out a PA program called…
- Trial name
- NCT06842849
- Testing
- Exercise program
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Sarcopenia
Exercise and Nutrition for Healthy AgeiNg
The aim of this randomized placebo-controlled 5-arm clinical trial is to evaluate the effect of combined anabolic interventions compared to single or placebo interventions on physical performance in community-dwelling…
- Trial name
- ENHANce (NCT03649698)
- Testing
- Home-based training program, High-quality protein supplement, Omega-3 fatty acid
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Frail Elderly Syndrome, Sarcopenia
Physical Fitness, Body Composition and Frailty in Elderly People.Exercise Program Effecsts. EXERNET Elder 3.0
One of the major changes occurring in developed societies is a significant ageing of the population. Nowadays, because of an enhanced life expectancy, 17% of the Spanish population is composed of people over 65 and the number is…
- Conditions
- Frail Elderly Syndrome, Sarcopenia, Physical Activity
- Trial name
- EXERNETElder (NCT03831841)
- Testing
- Multicomponent exercise programe
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza