Clinical trials: Physical Function, open to volunteers
Fontan Procedure, Fontan Circulation
A Simple Method for Monitoring the End-organ Function in Patients With Fontan Circulation.
This is a multicenter, observational, cross-sectional study designed to investigate whether a parsimonious set of low-cost, accessible functional, anthropometric, and physiological measurements can help identify multisystem…
- Trial name
- NCT07874165
- Volunteers
- 150 people
- Sponsor
- Universidad de Murcia
Transcranial Direct Current Stimulation, Autistic Spectrum Disorder
Cumulative and Booster Effects of Multisession Prefrontal Transcranial Direct Current Stimulation in Adolescents With ASD
Autism spectrum disorder (ASD) is a pervasive and lifelong developmental disorder that currently affects 1 in 54 children. Individuals with autism are often severely impaired in communication, social skills, and cognitive…
- Conditions
- Transcranial Direct Current Stimulation, Autistic Spectrum Disorder, Electroencephalography, Booster Effects
- Trial name
- NCT05492032
- Testing
- Active-tDCS, Cognitive training
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The Hong Kong Polytechnic University
COPD
Prospective Dynamic Cohort Study of Phenotypic Profiles in Patients With Chronic Obstructive Pulmonary Disease
This prospective, multicenter, real-world observational cohort study will describe phenotypic profiles, patient characteristics, and treatments in adults with stable chronic obstructive pulmonary disease (COPD).
- Trial name
- COPD-BPCO 2 (NCT07627763)
- Testing
- Routine care / no study-specific intervention
- Where
- 7 sites in France
- Volunteers
- 500 people
- Sponsor
- Initiatives Bronchopneumopathie Chronique Obstructive (BPCO)
Chronic Kidney Diseases, Metabolic Syndrome
Theory-based Health Behaviour Change Intervention in Patients of Metabolic Syndrome With Chronic Kidney Disease
The pilot study will adopt a 2-arm, pretest-posttest, and assessor-blind randomized controlled trial design to examine the feasibility and acceptability of a theory-based health behaviour change intervention and examine its…
- Trial name
- NCT06527768
- Testing
- Theory-based health behaviour change interventio
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Heart Failure With Reduced Ejection Fraction (HFrEF)
RELIEVE METAB Study
This prospective, single-center post-market-follow-up study aims to fill knowledge gaps by combining advanced cardiac MRI/MRS with systemic mitochondrial assays and exercise testing to characterize the energetic and functional…
- Trial name
- NCT07555925
- Testing
- cardiac MRI, Functional Testing
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Respiratory Monitoring, Thoracic Surgery
AirGo™ Respiratory Monitoring in Lung Resection
Patients undergoing lung resection surgery may experience changes in respiratory function during the perioperative period. Current monitoring methods provide important clinical information but are often limited to specific time…
- Conditions
- Respiratory Monitoring, Thoracic Surgery, Lung Resection Surgery, Respiratory Function
- Trial name
- NCT07838025
- Testing
- AirGoTM system
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI)
CPAP Randomized Controlled Trial
The overall goal of this randomized controlled trial is to test the hypothesis that in older adults with mild cognitive impairment (MCI) and previously untreated obstructive sleep apnea (OSA), 4 months of web-based sleep…
- Conditions
- Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI), Cognitive Decline Prevention in Pre-frail Older Adults
- Trial name
- NCT06773416
- Testing
- CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health, Delayed CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health
- Where
- Canada
- Volunteers
- 206 people
- Sponsor
- Sunnybrook Health Sciences Centre
the Elderly, Respiratory Disorders
Effects of Pulmonary Rehabilitation in Salt Chambers on Functional Efficiency, Respiratory Parameters, and Blood Rheology in Elderly With Respiratory Diseases.
The aim of the study is to assess the impact of the rehabilitation and treatment stay at the underground Health Resort of the 'Wieliczka' Salt Mine in Wieliczka on the functional capacity, respiratory parameters, and rheological…
- Trial name
- PRSC-FERPBR (NCT06951633)
- Testing
- Subterranean, pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 33 people
- Sponsor
- University School of Physical Education, Krakow, Poland
Heart Failure, Coronary Artery Disease
Ultrastructural Characteristics of Mitochondria in Cardiomyocytes in Heart Failure
According to modern concepts, mitochondrial dysfunction may be the fundamental basis for the development and progression of CHF, including in patients undergoing myocardial revascularization.
- Trial name
- MITOCH-HF (NCT05770349)
- Testing
- coronary artery bypass grafting
- Where
- Russia
- Volunteers
- 45 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Hallux Valgus
Foot Orthoses in the Treatment of Painful Hallux Valgus
This randomized pilot feasibility trial will evaluate the feasibility of conducting a full-scale randomized controlled trial comparing custom-made, prefabricated, and sham foot orthoses in people with painful hallux valgus.
- Trial name
- NCT07781735
- Testing
- Podiatric Education, Exercise, Prefabricated foot orthoses
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Université du Québec à Trois-Rivières
Hemiplegia, Stroke
Effects of Wearable Vibratory Devices on Arm Function in Subacute Stroke Patients
Hemiplegia, or paralysis of one side of the body, often results from stroke and severely limits arm function. Standard physiotherapy helps, but recovery is often slow.
- Trial name
- WEVIB-HEMI (NCT07641790)
- Testing
- Wearable Focal Muscle Vibrator
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Stroke
Understanding Motor Function in Stroke Patients and Their Functional Brain Reorganization Using Ultra High-field MRI
The MOTIF-STROKE study is embedded within the BrainSync project, aiming to develop innovative strategies for motor rehabilitation of the upper limb.
- Trial name
- MOTIF-STROKE (NCT07339813)
- Testing
- Functional MRI (fMRI) Acquisition
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
PARKINSON DISEASE (Disorder), Parkinson s Disease
Effects of Accelerated rTMS On Motor and Cognitive Function in Parkinson's Disease
Parkinson's disease (PD) is a brain disorder that causes progressive problems with movement, such as slowness, stiffness, tremor, and difficulty walking. Many people with PD also develop problems with thinking and memory.
- Trial name
- NCT07554833
- Testing
- TMS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- San Francisco Neurology and Sleep Center
Hypertrophic Cardiomyopathy, Heart Diseases
Comparison of the Effects of Inspiratory Muscle Training and Baduanjin Exercises in Hypertrophic Cardiomyopathy Patients
The study aims to compare the effects of inspiratory muscle training and Baduanjin exercises on pulmonary function, exercise capacity, and quality of life in patients with hypertrophic cardiomyopathy.
- Trial name
- NCT06490250
- Testing
- Inspiratory Muscle Training, Baduanjin Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul University - Cerrahpasa
Multiple Sclerosis
The Effects of Synchronous and Asynchronous Pilates Training Based on Telerehabilitation on Core Stabilization, Balance, Cognitive Functions, and Quality of Life in Individuals With Multiple Sclerosis: A Single-Blind Randomized Controlled Trial
This study will compare live video-based and prerecorded video-based Pilates programs in 38 adults aged 18-65 years with multiple sclerosis. Participants will be randomly assigned to one of two groups.
- Trial name
- NCT07893925
- Testing
- Synchronous Telerehabilitation-Based Pilates, Asynchronous Telerehabilitation-Based Pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Yuzuncu Yil University
Low Back Pain
Online Versus Physically Supervised Pilates Exercise Program in Non-specific Low Back Pain
The study will be Randomized Controlled Trial and will be conducted in Riphah Rehabilitation Research Center. The study duration will be 9 months. Non- probability convenient sampling technique will be used to collect the data.
- Trial name
- NCT07026097
- Testing
- Pilates Exercise - Online, Pilates Exercise - Supervised
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries
Correlation Between Psychological Readiness, Knee Function, and Isokinetic Performance After Anterior Cruciate Ligament Reconstruction (ACLR) Using Peroneus Longus Tendon Graft (PL-ACL-2025)
This clinical trial aims to investigate the correlation between psychological readiness, knee function, and isokinetic performance after anterior cruciate ligament reconstruction (ACLR) using the Peroneus Longus tendon graft…
- Conditions
- Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries, Knee Injuries
- Trial name
- PL-ACLR (NCT07201597)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema
Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials
The goal of this clinical trial is to evaluate the evolution of a cardiac ultrasound index (E/E') during 3 spontaneous breathing trials in Intensive Care Unit (ICU) adults (over 18 years) patients at risk for weaning failure.
- Conditions
- Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema, Weaning Failure of Mechanical Ventilation, Spontaneous Breathing Test
- Trial name
- ATARI (NCT06923267)
- Testing
- No Pressure Support No Positive End Expiratory Pressure Spontaneous Breathing Trial, Pressure Support Spontaneous Breathing trial, Humidified High Flow Spontaneous Breathing Trial
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Genetic Disease, Chopra-Amiel-Gordon Syndrome
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome
The purpose of this study is to establish the longitudinal natural history of individuals with confirmed or suspected Chopra-Amiel-Gordon Syndrome (CAGS) to learn more about the range of symptoms, changes in the structure of the…
- Conditions
- Genetic Disease, Chopra-Amiel-Gordon Syndrome, CAGS, ANKRD17
- Trial name
- CAGS NHS (NCT05528744)
- Testing
- Observational Study, Sample collection only
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Boston Children's Hospital
Female Sexual Dysfunction (FSD)
Impact of Tibial Nerve Stimulation on Lumbopelvic Mechanics and Sexual Function in Females With Sexual Dysfunctions
This study will be conducted to examine the effects of Transcutaneous Tibial Nerve Stimulation (TTNS) on lumbopelvic mechanics and sexual function in females with sexual dysfunctions and low back pain
- Trial name
- NCT07764445
- Testing
- Pelvic floor exercise, transcutaneous tibial nerve stimulation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
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