Clinical trials: Physical Function Improvement
Reduction of Blood Pressure in Hypertensive Patients., Improvement of Cardiovascular Autonomic Control.
Effects of Inspiratory Muscle Training on Cardiovascular Function in Hypertension.
The purpose of this study is to determine inspiratory muscle training effects on blood pressure, functional capacity and quality of life in hypertensive patients.
- Conditions
- Reduction of Blood Pressure in Hypertensive Patients., Improvement of Cardiovascular Autonomic Control., Improvement of Functional Capacity., Improvement of Quality of Life.
- Trial name
- TREMVEN (NCT01250444)
- Testing
- Inspiratory Muscle Training
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Cerebral Palsy Spastic Diplegia
Gait Improvement After Increased Frequency of Robot-assisted Gait Training in Cerebral Palsy Children
Robot-assisted gait training (RAGT) can provide a longer training duration with a higher repetition of stepping while maintaining a stable pattern of movement. However, the existing evidence of its effectiveness is not clear.
- Trial name
- NCT05412485
- Testing
- Robotic assisted gait training
- Where
- United Arab Emirates
- Volunteers
- 20 people
- Sponsor
- University of Sharjah
Post-COVID ME/CFS
Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo in Participants With Post-COVID-19 Syndrome
The goal of this clinical trial is to evaluate the therapeutic value of an approved drug (Vericiguat) in patients with post-COVID-19 syndrome, who suffer from profound tiredness or fatigue, regardless of bed rest.The main…
- Trial name
- NCT05697640
- Testing
- Vericiguat Oral Tablet
- Where
- Germany
- Volunteers
- 104 people
- Sponsor
- Charite University, Berlin, Germany
Angina Pectoris, Kuanzhong Aerosol
Bidirectional Cohort Study on Improvement of Quality of Life in Patients After Coronary Intervention With Kuanxiong Aerosol
The goal of this observational study is to compare in patients with Angina Pectoris after PCI for Coronary Heart Disease. The main questions it aims to answer are: To evaluate the effect of Kuanxiong Aerosol on the quality of…
- Conditions
- Angina Pectoris, Kuanzhong Aerosol, Quality of Life, Cardiac Function
- Trial name
- NCT06480097
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Mild Dementia
The Efficacy and Safety of tDCS in Patients With Mild Dementia
This study evaluated the effectiveness and safety of improving Mild Dementia by applying tDCS for 26 weeks to patients with Mild Dementia.
- Trial name
- NCT05495113
- Testing
- YMS-201B (Device: Mind STIM)
- Where
- 2 sites in South Korea
- Volunteers
- 118 people
- Sponsor
- Ybrain Inc.
Migraine
Imaging the Migraine Brain Pre- and Post-Erenumab
Researchers are trying to determine if there is a difference between brain images of subjects that do respond to treatment with erenumab and subjects who do not respond to treatment with erenumab using Magnetic Resonance Imaging…
- Trial name
- NCT03773562
- Testing
- Erenumab
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Adults Aged 18-45 Years
The Safety and Efficacy of Probiotic for Improving Intestinal and Immune Function
To evaluate the safety and efficacy of Streptococcus salivarius subsp. thermophilus ST36 in healthy adults on immune function and intestinal health.
- Trial name
- NCT06779994
- Testing
- Probiotic
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Bronchial Asthma
Two Inhalation Methods Using a Pressurized Metered Dose Inhaler With Valved Holding Chamber to Assess Improvement in Lung Function After SABA Administration in Bronchial Asthma
Bronchial asthma is a chronic inflammatory disorder characterized by recurrent reversible episodes of breathlessness, wheezing, chest tightness and/ or cough.
- Trial name
- NCT05428956
- Testing
- Single Inhalation technique, Tidal inhalation technique
- Where
- 2 sites in India
- Volunteers
- 897 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Adhesive Capsulitis
MRI and Clinical Predictive Factors of the Response to Arthrographic Distension in Severe Capsulitis
The purpose of this study is to identify clinical and MRI factors associated to a better response to arthrographic distension in patients with severe capsulitis.
- Trial name
- IRCAP (NCT04653636)
- Testing
- Arthrographic distension, Immediate joint mobilization
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility, Male
Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
This is a study of infertility which often occurs in men with spinal cord injury. Most men with spinal cord injury have a normal sperm count but abnormally low sperm motility - which means that the sperm does not swim well.
- Trial name
- NCT05903859
- Testing
- Probenecid 500 Milligrams (mg), probenecid 250 Milligrams (mg)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Miami
Exercise, Parkinson Disease
Comparing the Effects of Instability Resistance Training Versus Aerobic Training on Cognitive and Motor Improvements Found in Parkinson's Disease Participants
This study will be looking at the effects that instability resistance training and aerobic training, individually, have on the improvement of various motor and cognitive impairments present in individuals with Parkinson' disease.
- Trial name
- NCT03711955
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Cancer, Cachexia; Cancer
Improvement of Neuromuscular Function, Fatigue and Quality of Life by Optimizing Muscle Building and Nutrition in Colorectal Cancer: a Pilot Study
This study is based on the assumption that muscle strength and muscle mass will be better preserved in an "intervention" group with specific management combining retraining and nutritional monitoring compared to the "no…
- Trial name
- ColCanter (NCT04136249)
- Testing
- Over physical activity
- Where
- France
- Volunteers
- 30 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Peripartum Cardiomyopathy
Effect of Bromocriptine on Left Ventricular Function in Women With Peripartum Cardiomyopathy
This is a randomized, controlled clinical trial to evaluate the efficacy and safety of bromocriptine for improvement of left ventricular function of women with Peripartum cardiomyopathy (PPCM). A Multi center trial in Germany.
- Trial name
- PPCM (NCT00998556)
- Testing
- Bromocriptine
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Hannover Medical School
Aging, Vestibular Disorder
Comprehensive Geriatric Assessment in the Monitoring of Functional Improvement
14.44% of the Spanish population is over 70 years old and Aging as a normal process is characterized by gradual modifications in the physiological functions of the different systems, so that as age progresses, deterioration can…
- Conditions
- Aging, Vestibular Disorder, Physiotherapy, Physical Activity
- Trial name
- NCT04894929
- Testing
- multi component exercise in the clinic, vestibular exercise in the clinic, vestibular exercise at home telerehabilitation
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- University of Seville
Mild Cognitive Impairment
Study of tDCS for Mild Cognitive Impairment
The primary objective of this study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Mild Cognitive Impairment (MCI)
- Trial name
- NCT02320890
- Testing
- YBand (YDT-201N)
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Incheon St.Mary's Hospital
Parkinson Disease
Strategy for Daily Activity Improvement in Patients With Parkinson's Disease
The symptoms and signs of patients with Parkinson's disease (PD) include bradykinesia, rigidity, tremor and poor sensory integration, which result in mobility disability.
- Trial name
- Parkinson (NCT03972241)
- Testing
- foot insole
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kwan-Hwa Lin
Tricuspid Insufficiency, Tricuspid Regurgitation (TR)
PASCAL Precision-GDMT Registry
The goal of this observational study is to demonstrate that successful tricuspid valve repair with the PASCAL Precision System in participants with at least severe tricuspid insufficiency and left ventricular dysfunction will be…
- Conditions
- Tricuspid Insufficiency, Tricuspid Regurgitation (TR), Left Ventricular Cardiac Dysfunction, Left Ventricular (LV) Systolic Dysfunction
- Trial name
- PASCAL (NCT07578129)
- Volunteers
- 50 people
- Sponsor
- Ceric Sàrl
It is Possible That Amadeo Will Guarantee a Greater Clinical Improvement as Compared to an Occupational Therapy Thanks to the Strengthening of Brain Plasticity
Improving Hand Motor Function After Stroke: Role of Robotics
Two recent randomized clinical trials reported a significant contribute of Amadeo toward the recovery of hand motor function in acute stroke patients in association with physiotherapy and/or occupational therapy.
- Trial name
- NCT03292276
- Testing
- Amadeo Training
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Pulmonary Arterial Hypertension, Insulin Resistance
Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE)
The purpose of this study is to investigate the extent to which diet and exercise may improve PAH through the modulation of insulin sensitivity.
- Trial name
- NCT03288025
- Testing
- Nutrition and Exercise
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The Cleveland Clinic
Depressive Symptoms, Urinary Incontinence
BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women
The goal of this clinical trial is to evaluate if the combined treatment with EXOMIND (BTL-699-2) and EMSELLA (HPM-6000UF) devices is able to improve depressive symptoms and sexual function in women who are perimenopausal or…
- Conditions
- Depressive Symptoms, Urinary Incontinence, Sexual Dysfunction
- Trial name
- NCT07413705
- Testing
- EXOMIND (BTL-699-2) Active Treatment, EMSELLA (HPM-6000UF) ActiveTreatment
- Where
- 3 sites in United States, Canada
- Volunteers
- 41 people
- Sponsor
- BTL Industries Ltd.