Clinical trials: Physical Function Improvement
Intestinal Disease
Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel Resection
The purpose of this research study is to see the outcome of Sugammadex versus Neostigmine with Glycopyrrolate in colorectal surgery as it relates to its effects on post-surgical time (in hours) to first bowel movement and…
- Trial name
- NCT06112353
- Testing
- Neostigmine Injectable Solution, Sugammadex injection
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, Irvine
Congestive Heart Failure
Peritoneal Dialysis in Congestive Heart Failure
Rationale: End-stage congestive heart failure is a serious invalidating condition with a poor prognosis and increasing incidence.
- Trial name
- PDinCHF (NCT01124227)
- Testing
- icodextrin
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Martini Hospital Groningen
Amblyopia
Visual Functional Connectivity and Visual Improvement After TMS/Binocular Treatment
The purpose of this study is to assess the effectiveness of combining binocular treatment with repetitive transcranial magnetic stimulation (rTMS) in improving the vision of adults with amblyopia.
- Trial name
- NCT03151200
- Testing
- Computer based binocular treatment, Transcranial magnetic stimulation
- Where
- Canada
- Sponsor
- University of Manitoba
Dairy Products, Whey Protein
High Protein Dairy Products and Resistance Exercise in the Elderly
Protein supplementation is one of the main recommendations for regular endurance physical exercise (RT). In older people, the need for protein increases particularly in the face of physiological and pathophysiological changes…
- Conditions
- Dairy Products, Whey Protein, Resistance Training, Older Adults
- Trial name
- NCT06412302
- Testing
- Whey Protein+Resistance Training, High protein yogurt+Resistance Training
- Where
- Chile
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidad de O´Higgins
Deglutition Disorders
Clinical Trial on the Safety and Efficacy of Optimized Transcranial Direct Current Stimulation for the Swallowing Function in Patients With Post-Stroke Dysphagia
The goal of this clinical trial is to evaluate whether the application of optimized transcranial direct current stimulation is more effective compared to sham stimulation for temporary improvement of swallowing function in…
- Trial name
- NCT06305949
- Testing
- Optimized transcranial Direct Current Stimulation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- NEUROPHET
Rheumatic Heart Disease, Coronary Heart Disease
Validity Study of Glutamine to Improve Cardiac Function in Cardiac Surgery
In view of the lack of large-scale clinical study and potent evidence-based medicine, the investigators designed a randomized, double-blind, placebo-controlled study to ascertain whether preoperative intravenous administration…
- Trial name
- NCT01794884
- Testing
- Glutamine, Ringer's solution
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Yuejiang Liu
Abnormal Mental State, Schizophrenia
Effects of 'Seroquel-XR' on the Improvement of Neurocognitive Function in People At-risk Mental States(ARMS)
The primary objective of this study is to assess the effects of 'Seroquel-XR' on the verbal learning ability in people with at-risk mental state (ARMS) over a 12 week period.
- Trial name
- ES-ARMS (NCT01250847)
- Testing
- Quetiapine(Seroquel-XR) 50~800mg a day
- Where
- 2 sites in South Korea
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Severance Hospital
It is Possible That Amadeo Will Guarantee a Greater Clinical Improvement as Compared to an Occupational Therapy Thanks to the Strengthening of Brain Plasticity
Improving Hand Motor Function After Stroke: Role of Robotics
Two recent randomized clinical trials reported a significant contribute of Amadeo toward the recovery of hand motor function in acute stroke patients in association with physiotherapy and/or occupational therapy.
- Trial name
- NCT03292276
- Testing
- Amadeo Training
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Brain Neoplasms, Child
Effectiveness of Musical Training in Children Surviving Brain Tumours
This study aims to examine the effects of musical training on improving the neurocognitive function and psychological well-being of children surviving brain tumours.
- Trial name
- NCT02754908
- Testing
- musical training, tutoring classes
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Post-COVID ME/CFS
Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo in Participants With Post-COVID-19 Syndrome
The goal of this clinical trial is to evaluate the therapeutic value of an approved drug (Vericiguat) in patients with post-COVID-19 syndrome, who suffer from profound tiredness or fatigue, regardless of bed rest.The main…
- Trial name
- NCT05697640
- Testing
- Vericiguat Oral Tablet
- Where
- Germany
- Volunteers
- 104 people
- Sponsor
- Charite University, Berlin, Germany
Impaired Synaptic Plasticity, Impaired Cognition
Synaptic Plasticity and Cognitive Function in RASopathies
The project is targeting cognitive impairment, one of the main health problems of patients with RAS pathway disorders. The aim of this study is to translate findings of animal studies to humans.
- Trial name
- SynCoRAS (NCT03504501)
- Testing
- Lovastatin, Lamotrigine
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Worksite Health Promotion, Lifestyle Risk Reduction
Worksite Wellness Within Long-term Care Facilities
The goal of this proposed study is to test the feasibility and preliminary efficacy of worksite wellness program designed to reduce worker stress (job and personal) and improve cardiovascular disease among long-term care workers.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Cardiovascular Diseases, Occupational Stress
- Trial name
- NCT04166643
- Testing
- WHHIP PLUS, Education only control
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Parkinson Disease
Speed Manipulated Adaptive Rehabilitation Therapy Bike for Parkinson's Disease
Parkinson's disease (PD) is a progressive neurological disorder that results in slowness of movement, muscle stiffness, tremor, and postural instability.
- Trial name
- SMART (NCT05361200)
- Testing
- Dynamic high-cadence cycling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kent State University
Osteoarthritis
Study of Effectiveness of Hand Exercises to Treat Symptoms of Hand Osteoarthritis
Participants in this study will do hand exercises once per day for 16 weeks. The purpose of the study is to determine if hand exercises designed to improve range of movement and strength are an effective way to decrease…
- Trial name
- NCT00375947
- Testing
- Hand Exercise
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The Arthritis Research Institute of America
Type 2 Diabetes Mellitus, Overweight
Effects of Low Versus High Carbohydrate Diet During Rehabilitation on Cardiovascular Function and Metabolism in Type 2 Diabetes
Compared to the traditional low fat diet for overweight patients with type 2 diabetes, recent evidence shows that low carbohydrate/high protein diets lower triglycerides and postprandial glucose levels more effectively.
- Trial name
- NCT01004757
- Testing
- LOGI diet, Low Fat diet
- Where
- Germany
- Volunteers
- 41 people
- Sponsor
- Munich Municipal Hospital
Mild Cognitive Impairment
A Pilot Study of tDCS for Mild Cognitive Impairment
The primary objective of this preliminary study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Mild Cognitive Impairment (MCI)
- Trial name
- NCT02227966
- Testing
- Yband (YDT-201N)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Alzheimer's Disease
A Pilot Study of tDCS for Mild to Moderate Alzhemier's Disease
The primary objective of this preliminary study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Alzheimer's disease
- Trial name
- NCT02227953
- Testing
- Yband (YDT-201N)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Multiple Sclerosis
Study of Exercise on Impact of Cognitive Functioning in Multiple Sclerosis Patients
Cognitive impairment affects roughly 50% of people with multiple sclerosis (MS). There are currently no satisfactory medical treatments for cognitive impairments related to MS and alternative forms of treatment are needed.
- Trial name
- NCT02106052
- Testing
- Aerobic exercise, Stretching and toning exercise
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Washington
Uterine Neoplasms
ERAS (Enhanced Recovery After Surgery) Protocol Implementation in Piedmont Region for Hysterectomy.
The study assesses the impact on quality of care of implementing the ERAS (Enhanced Recovery After Surgery) protocol for hysterectomy of benign or malignant tumors of the uterus in the network of public hospitals in the Regione…
- Trial name
- ERAS-Gyneco (NCT04063072)
- Testing
- ERAS protocol
- Where
- Italy
- Volunteers
- 1,800 people
- Sponsor
- Ospedale Regina Montis Regalis
Myocardial Viability in Ischemic Left Ventricular Dysfunction, Prediction for Improvement in Cardiac Function After Revascularization Therapy
The Use of Myocardial Deformation Imaging
Myocardial deformation imaging allows analysis of myocardial viability in ischemic left ventricular dysfunction. This study will evaluate the predictive value of myocardial deformation imaging for improvement in cardiac function…
- Trial name
- NCT00476320
- Testing
- Magnetic Resonance Imaging, Revascularization, Echocardiography with myocardial deformation imaging
- Where
- Germany
- Sponsor
- RWTH Aachen University