Clinical trials: Physical Health Functioning
Obesity, Metabolic Syndrome
Investigating the Possible Link Between Habitual Diet, Physical Activity, Sleeping Patterns, Obesity Status and Age With Gut Bacterial Composition, Gut Barrier Function, Metabolic Endotoxemia, Systemic Inflammation and Glycaemic Control.
In the UK, 25% of the adults are affected by metabolic syndrome (NHS, 2016). Metabolic syndrome is a cluster of different conditions including: hyperglycaemia, insulin resistance hypertriglyceridemia, dyslipidaemia and…
- Conditions
- Obesity, Metabolic Syndrome, Insulin Resistance
- Trial name
- NCT03864107
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Health-Related Quality of Life, Physical Activity
Prosocial Behavior and Exercise Among Older Adults
The purpose of this study is to compare two exercise programs to determine how well they help older adults make exercise a regular habit after 9 months.
- Conditions
- Health-Related Quality of Life, Physical Activity, Physical Function
- Trial name
- NCT00747019
- Testing
- Prosocial Behavior Physical Activity (PBPA), Physical Exercise (PE)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Disability Physical
Sexual Function and Quality of Sexual Life in Women With Physical Disabilities
This pilot randomized controlled trial will be carried out with women with physical disabilities registered at a disability center.
- Trial name
- NCT07042646
- Testing
- Sexual and Reproductive Health Training program
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Amasya University
Cognitive Function, Physical Function
Effects of Exercise Board Games on Cognitive Function in Older Adults
This study aims to evaluate the effects of an exercise-based board game intervention on cognitive function, physical function, and health promotion among community-dwelling older adults.
- Trial name
- NCT07586696
- Testing
- Exercise-Based Board Game Intervention
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Aging, Cognitive Function 1, Social
Effects of Physical and Cognitive Training in Neuroplasticity, Health and Cognition. Movement Project
The MoveMent project applies non-pharmacological strategies - physical exercise and cognitive training - that have been shown to be effective in promoting active and healthy aging.
- Trial name
- NCT03123900
- Testing
- Physical exercise, Cognitive training, Combined training
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Older Adults
The Effect of IoT-based Smart Exercises System in the Senior Adults: Resistance Band Training System
Subjects are divided into two groups, (1) Control (Ctrl) and (2) Smart Exercise (SE) group. Participants in the Ctrl group are instructed to perform resistance band training twice weekly according to a paper-based exercise guide…
- Trial name
- NCT07772713
- Testing
- Smart Elastic Band App, Paper-based Resistance Band Exercise Guide
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Aging, Longevity
Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life
The LONG-LIFE study is a randomized Phase I, dose-ranging trial designed to evaluate whether psilocybin impacts aging-related biomarkers, cognitive function, and purpose/meaning in life in medically stable older adults.
- Conditions
- Aging, Longevity, Biomarkers of Aging
- Trial name
- LONG-LIFE (NCT07719088)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charles Raison
Aging, Health Promotion
Social Prescribing Intervention for Health Promotion in Community-Dwelling Older Adults
This study evaluates the effects of a social prescribing intervention on health promotion outcomes in community-dwelling older adults.
- Conditions
- Aging, Health Promotion, Mental Health
- Trial name
- NCT07540117
- Testing
- Mindfulness Meditation and Walking-Pole Exercise
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Breast Cancer
Lifestyle Intervention for High Risk Cancer Survivors
The goal of this behavioral research study is to find out more about the health behaviors of cancer survivors. Researchers want to understand the cultural, social, and environmental factors related to physical activity and…
- Trial name
- NCT01508273
- Testing
- Exercise Program, Website, Exercise DVD
- Where
- 3 sites in United States
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Functional Fitness, Health Promotion
12-week Pilates Program on Community-dwelling Middle-aged Women
The purpose of this study was to investigate the effects of a Pilates exercise intervention program on functional physical fitness in community-dwelling middle-aged women.
- Conditions
- Functional Fitness, Health Promotion, Exercise, Frail Elderly Syndrome
- Trial name
- NCT05333484
- Testing
- Programed Pilates
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Cardiac Rehabilitation, Acute Coronary Syndrome
The Influence of Cardiac Rehabilitation on the Health State After ACS
Coronary heart disease, including acute coronary syndromes (ACS), is the leading cause of death in European countries. One of the basic elements of secondary and tertiary prevention of ACS is cardiac rehabilitation.
- Trial name
- CARDIO-REH (NCT03935438)
- Testing
- Cardiac rehabilitation
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Cancer
Development and Validation of a Health-related Quality of Life Instrument
This study aims to develop a health related quality of life (HRQOL) patient reported outcome (PRO) for patients receiving immune checkpoint modulator (ICM) therapy.
- Trial name
- FACT-ICM (NCT02651831)
- Testing
- Focus groups and individual interviews, Questionnaire
- Where
- Canada
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Regular Physical Activity, Exercise
Investigation of the Effectiveness of Regular Physical Activity in University Students
In our study, university students who coded the course from various faculties and departments within the scope of a university-wide free elective course, after regular physical activity; It was aimed to examine the effects on…
- Trial name
- NCT06329115
- Testing
- Exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Sarcopenia, Physical Inactivity
Women in Action: A Multicomponent Intervention for Older Women
"Women in Action" is a quasi-experimental, mixed-methods study evaluating a 16-week multicomponent intervention (supervised strength/aerobic/balance training plus psychoeducational and nutrition-focused behavioral workshops) for…
- Conditions
- Sarcopenia, Physical Inactivity, Menopause, Healthy Aging
- Trial name
- WIA (NCT07860424)
- Testing
- Multicomponent exercise, nutrition, and psychoeducational program
- Where
- 2 sites in Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Cognitive Change, Beta-Thalassemia
Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta Thalassemia
This study aims to: Assess the cognitive function in children with beta thalassemia Evaluate the fatigue in beta thalassemic children Assess the health related quality of life measures in children with beta thalassemia.
- Conditions
- Cognitive Change, Beta-Thalassemia, Fatigue, Quality of Life
- Trial name
- NCT05469230
- Where
- Egypt
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Cairo University
Physical Inactivity, Healthy Aging
Cost-effectiveness and Efficacy of Different Physical Exercise Interventions (ExerMOT4Health)
Online exercise has increased in popularity during the pandemic, but there is no evidence of its feasibility and benefits in older people and the influence of motivational strategies.
- Conditions
- Physical Inactivity, Healthy Aging, Older Adult
- Trial name
- ExerMOT4Health (NCT06425679)
- Testing
- Supervised synchronous online exercise intervention without motivational strategies, Supervised synchronous online exercise intervention with motivational strategies, Supervised face to face exercise intervention without motivational strategies
- Where
- 2 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Cancer, Sedentary Behavior
Physical Function and Mental Health in Cancer Survivors
The goal of this observational study is to evaluate the joint prognostic effects of physical function and mental health on survival of cancer survivors.
- Conditions
- Cancer, Sedentary Behavior, Depressive Symptoms, Survivorship
- Trial name
- NCT06439316
- Testing
- Sedentary behavior, Depressive symptoms
- Volunteers
- 2,932 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport