Clinical trials: Physical Injury
Substance Use Disorders, Posttraumatic Stress Disorder
SUPER Study (Substance Use and PTSD Treatment Effectiveness Research Study)
This study proposes a prospective program of research that will identify feasible and inexpensive methods to detect and treat comorbid PTSD among VA SUD patients, thereby improving substance abuse treatment outcomes.
- Trial name
- NCT00265564
- Testing
- Modified Seeking Safety integrated into std outpatient SUD care, Standard outpatient SUD care
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- VA Office of Research and Development
Chronic Pain
Pain, Psychiatric Disorders, and Disability Among Veterans With and Without Polytrauma
We believe information to be obtained from this proposed study will prove critical for planning future VA healthcare strategies and developing effective and efficient treatments targeting pain and emotional adjustment…
- Trial name
- NCT00645970
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Head Trauma, Craniocerebral Injuries
Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas
The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the a portable near-infrared-based device (portable NIR-based device), the InfraScanner 2000™, to detect…
- Conditions
- Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries
- Trial name
- NCT04505293
- Testing
- InfraScanner 2000™
- Where
- 2 sites in United States, Uganda
- Volunteers
- 672 people
- Sponsor
- Duke University
Renal Failure, Acute Renal Failure
Premarket Clinical Safety Assessment of the ELISIO™-HX
The primary safety objective of this study is to evaluate the safety of the use of the high-permeability hemodialyzer series ELISIO™-HX, by showing that the pre-dialysis albumin levels are not affected using the investigational…
- Conditions
- Renal Failure, Acute Renal Failure, Chronic Renal Failure, Chronic Kidney Diseases
- Trial name
- NCT07058909
- Testing
- ELISIO™-HX Dialyzer
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Nipro Medical Corporation
Patient Satisfaction, Sports Injury
Virtual Phone Visits Compared to In-Person Physical Visits for Post-Operative Follow-Up at a Sports Medicine Clinic
This study will compare patient reported outcomes (PROs) of patients seen at virtual phone visits compared to in-person visits for 6 weeks, 12 weeks, and 6 months post-operative follow up at a sports medicine clinic.
- Conditions
- Patient Satisfaction, Sports Injury, Surgery, Orthopedic Disorder
- Trial name
- NCT05998148
- Testing
- virtual phone appointment visits
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Jonathan Wu
PTSD
Yoga and Physical Activity for Veterans
Posttraumatic stress disorder (PTSD) is a major health problem for the nation's Veterans, leading to significant physical and mental health morbidity and mortality.
- Trial name
- NCT03509909
- Testing
- Hatha yoga, Supportive physical activity
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic
Increasing Activity for Veterans With PTSD
The proposed work will be a key step forward in fulfilling the mission of VA RR\&D to restore function and enable social reintegration for Veterans.
- Trial name
- I CARE for Vet (NCT04383496)
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Lung Injury, Acute
SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS
This is an early phase (Phase IIa), randomized, double-blind, parallel group, multi-centre study for subjects with trauma (physical injury) who are at risk for developing Acute Lung Injury (ALI) or Acute Respiratory Distress…
- Trial name
- NCT00996840
- Testing
- SB-681323 Intravenous 3mg, SB-681323 Intravenous 7.5 mg, SB-681323 Intravenous 7.5mg
- Where
- 6 sites in United States
- Volunteers
- 77 people
- Sponsor
- GlaxoSmithKline
Atrial Fibrillation
Medical Need of OAC Reversal
This is a retrospective, observational, claims cohort study to assess, for adult patients initiating an oral anticoagulant for NVAF
- Trial name
- NCT03254147
- Testing
- warfarin, dabigatran, Apixaban
- Where
- Japan
- Volunteers
- 53,969 people
- Sponsor
- Boehringer Ingelheim
Physical Disability
A Community Wellness Program for Adults Living With Long-term Physical Disability
For people living with long-term physical disabilities, such as spinal cord injury or multiple sclerosis, middle-age (45-64) is a period of great vulnerability for losses in function and participation.
- Trial name
- EW-D (NCT03653390)
- Testing
- EnhanceWellness for Disability (EW-D), Wellness Education
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Washington
Head Trauma, Crushing Skull Injury
Detecting Traumatic Intracranial Hemorrhage With the InfraScanner 2500™ in Uganda
The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the portable near-infrared-based device (portable NIR-based device), the InfraScanner 2500™, to detect…
- Conditions
- Head Trauma, Crushing Skull Injury, Head Injury, Head Injuries, Multiple
- Trial name
- NCT06491173
- Testing
- InfraScanner 2500™
- Where
- 2 sites in Uganda
- Volunteers
- 180 people
- Sponsor
- Duke University
Disorder of Consciousness, Traumatic Brain Injury
Validity and Feasibility of the CRSR-FAST
The CRS-R is a standardized and validated bedside assessment of conscious awareness. It is used routinely for diagnosis and prognosis of patients with disorders of consciousness (DOC) as well as in research settings.
- Trial name
- CRSR-FAST (NCT03549572)
- Testing
- Coma Recovery Scale-Revised
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Wound of Lower Leg (Physical Finding)
Prontosan Quality of Life Study in Patients With Chronic Leg Wound(s)
This study evaluates the use of Prontosan® Wound Irrigation Solution and Prontosan® Wound Gel in the treatment of chronic leg wounds in adults.
- Trial name
- NCT03369756
- Testing
- Prontosan Wound Irrigation Solution and Prontosan Wound Gel
- Where
- 5 sites in United States
- Volunteers
- 43 people
- Sponsor
- B. Braun Medical Inc.
PTSD, Physical Injury
IT Enhanced Peer Integrated Collaborative Care for US Trauma Care Systems
This study evaluates two readily implementable approaches to the delivery of transitional care for injured patients treated emergently in US trauma care systems.
- Trial name
- TSOS 7 Peer (NCT03569878)
- Testing
- Peer-Integrated Multidisciplinary Collaborative Care, Trauma surgery team notification
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Washington
Injuries
The Use of Public Messaging for the Promotion of Firearm Safety to Veterans
This pilot study seeks to determine if exposure to the firearm safety public service announcement (PSA) developed by the U.S. Department of Veterans Affairs (VA) is associated with changes in related beliefs and safe storage…
- Trial name
- NCT03417752
- Testing
- Exposure to firearm safety PSA, Exposure to health promotion PSA
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- Canandaigua VA Medical Center
Diabetic Foot Ulcer
Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers
The purpose of the following prospective, randomized, controlled clinical trial is to compare synthetic hybrid-scale fiber matrix (Restrata®, Acera Surgical, Inc.) with standard of care in treating diabetic foot ulcers in human…
- Trial name
- NCT04918784
- Testing
- Restrata®, Wound Dressing
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Acera Surgical, Inc.
Injury Leg, Injury, Knee
Serial Movement Assessment in Collegiate Athletes Who Perform Injury Prevention Training
Athletic injury can result in decreased athletic performance or removal from sport participation. There may also be psychological and financial impacts of athletic injury.
- Conditions
- Injury Leg, Injury, Knee, Injury;Sports, Injury, Ankle
- Trial name
- NCT04748718
- Testing
- Exercise-based injury prevention program
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Northern Vermont University
Pressure Ulcers
P400 for Stage II-IV Pressure Ulcers in Home and Extended Care
To assess the efficacy of a pressure ulcer treatment mattress, the P400 mattress, in the treatment of multiple Stage II or one or more large Stage III or IV pressure ulcers in the home care and extended care (nursing home)…
- Trial name
- P400 (NCT01139879)
- Testing
- P400 mattress
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hill-Rom
Anterior Cruciate Ligament Rupture
Are Opioids Needed After ACL Reconstruction
As the public health sector continues to confront the opioid epidemic, orthopaedic surgeons must revisit pain management protocols to reduce unnecessary opioid prescriptions.
- Trial name
- NCT04285853
- Testing
- Oxycodone
- Where
- 3 sites in United States
- Volunteers
- 98 people
- Sponsor
- Emory University