Clinical trials: Physiological Dead Space
ARDS, Volumetric Capnography
Clinical and Physiological Assessment of a Nearly Ultra-protective Lung Ventilation Strategy: A Quasi-experimental Preliminary Study in ARDS Patients
This study aims to determine whether a protective mechanical ventilator strategy generates a reduction in the Bohr´s dead space in patients with moderate or severe acute respiratory distress syndrome (ARDS).
- Trial name
- NCT04435613
- Testing
- protective mechanical ventilation strategies
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Clinica las Condes, Chile
Acute Respiratory Distress Syndrome, Mechanical Ventilation
Physiological Studies in the Prone Position in Patients With ARDS
The purpose of this study is to observe the changes of physiological indicators such as ventilation and oxygenation in the prone position of ARDS patients, to observe the change trend of each patient's indicators, and to observe…
- Conditions
- Acute Respiratory Distress Syndrome, Mechanical Ventilation, Prone Positioning
- Trial name
- NCT06586736
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Elective Procedures Requiring Mechanical Ventilation
Evaluation of Novel Cardio-Pulmonary Physiological Monitor, the VQm PHM™, for Acute Care Medicine
This is a prospective, observational study to assess agreement of pulmonary health parameters measured by a new non-invasive physiologic monitor, the VQm pulmonary health monitor (PHM)™ with clinical gold standards.
- Trial name
- NCT04730063
- Testing
- VQm PHM™
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rostrum Medical Innovations Inc.
Ventilation Therapy; Complications
Physiological Dead Space Measured by Volumetric Capnography in BiPAP and APRV .
Background and Rationale : Mechanical ventilation is an essential component of the care of patients with respiratory failure.Biphasic positive Airway Pressure (BiPAP) and Airway Pressure release ventilation (APRV) are relatively…
- Trial name
- NCT03218943
- Testing
- APRV ventilation mode, BIPAP ventilation moood
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Oxygen Consumption, Sevoflurane
Oxygen Consumption and Sevoflurane Uptake Based on Physiological Dead Space Estimation
In this study, the investigators will evaluate whether the delivered fraction of oxygen (O2) and sevoflurane administered through a a closed circuit and calculated on the basis of the estimations of O2 consumption (VO2) and…
- Conditions
- Oxygen Consumption, Sevoflurane, Anesthetics, Inhalation, Surgery
- Trial name
- NCT05511584
- Testing
- VO2 estimation, SEVOup estimation
- Where
- Spain
- Volunteers
- 17 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Chronic Obstructive Pulmonary Disease
The Effect of Inhaled Nitric Oxide on Deadspace in COPD
Chronic obstructive pulmonary disease (COPD) is a progressive disease of the respiratory system that generally develops as a result of smoking.
- Trial name
- NCT04069052
- Testing
- Nitric Oxide
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Dr. Denis O'Donnell
Invasive Mechanical Ventilation, Ventilation-Perfusion Mismatch
Physiological Dead Space and Intensive Care Mortality in Mechanically Ventilated Patients
This study investigates the relationship between physiological dead space and clinical outcomes, specifically mortality and discharge status, in adult patients receiving invasive mechanical ventilation in the intensive care unit…
- Conditions
- Invasive Mechanical Ventilation, Ventilation-Perfusion Mismatch, ICU Mortality, Critical Illness
- Trial name
- IRIS-MAP (NCT06963944)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Karadeniz Technical University
Physiological Dead Space, Ventilation-Perfusion Mismatch
Correlation of EtCO₂- and P(A-a)O₂-Based Dead Space Calculations in Mechanically Ventilated ICU Patients
This study aims to evaluate two different methods for calculating physiological dead space in adult patients undergoing invasive mechanical ventilation in the intensive care unit (ICU).
- Conditions
- Physiological Dead Space, Ventilation-Perfusion Mismatch, Mechanical Ventilation, Enghoff Correction
- Trial name
- CODE-EtA (NCT06947486)
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Karadeniz Technical University
Tracheostomy, Prolonged Mechanical Ventilation
Incremental Dead Space Versus Capping Trial Before Tracheostomy Decannulation
Some critically ill patients need a breathing tube placed directly into the windpipe (tracheostomy) because they require long-term help from a breathing machine.
- Conditions
- Tracheostomy, Prolonged Mechanical Ventilation, Tracheostomy Decannulation
- Trial name
- NCT07810166
- Testing
- Incremental Instrumental Dead Space, Capping Trial
- Where
- Chile
- Volunteers
- 22 people
- Sponsor
- Pontificia Universidad Catolica de Chile
ARDS, Human, Mechanical Ventilation Complication
Smartphone Application for Initiation of Protective Ventilation. Clinical Impact of Instrumental Dead Space Reduction
Clinical evaluation of a new educative tools (Smartphone application) based on impact of instrumental dead space reduction after initiation of protective ventilation during mechanical ventilation.
- Conditions
- ARDS, Human, Mechanical Ventilation Complication, Humidifier Lung
- Trial name
- Ventilo (NCT04390360)
- Testing
- Protective ventilation implementation, Protective ventilation with HME, Protective ventilation with Heated humidifier
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Laval University