Clinical trials: Physiological Responses
Primary Ciliary Dyskinesia
Physiological Responses to Exercise Tests in Primary Ciliary Dyskinesia Compared With Healthy Individuals
The individuals with primary ciliary dyskinesia (PCD) have lower aerobic fitness and anaerobic performance than healthy individuals.
- Trial name
- NCT05712798
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Eating Disorders (Excluding Anorexia Nervosa)
CBT Effects on Neural, Physiological, and Attentional Responses in Anorexia Nervosa
This randomized controlled trial investigates the neurophysiological, physiological, and attentional effects of Cognitive-Behavioral Therapy (CBT) in individuals with restrictive-type anorexia nervosa (AN).
- Trial name
- NCT07037017
- Testing
- Cognitive-Behavioral Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Nisantasi University
Obstructive Sleep Apnea, Erectile Dysfunction
Changing Lifestyle in OSA Males Who Suffer Metabolic Syndrome and Impotence: Is There a Response?
The problems like metabolic syndrome and sexual impotence in males with obstructive sleep apnea are common. continuous passive airway pressure (CPAP) is an authorized treatment for this type of apnea but still the recommendations…
- Conditions
- Obstructive Sleep Apnea, Erectile Dysfunction, Metabolic Syndrome
- Trial name
- NCT06960746
- Testing
- lifestyle changing plus CPAP, CPAP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Exercise Physiology, Sports Nutrition
Effects of Acute Beetroot Juice on Aerobic Performance and Muscle Oxygenation in Amateur Female Soccer Players
Effects of Acute Beetroot Juice on Aerobic Performance and Muscle Oxygenation in Amateur Female Soccer Players
- Conditions
- Exercise Physiology, Sports Nutrition, Cardiorespiratory Fitness
- Trial name
- NCT07840014
- Testing
- Nitrate-rich beetroot juice
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sakarya Applied Sciences University
Sport Participation
Running Environments on Physiological Responses, Emotion, Motivation, and Attention
The goal of this clinical trial is to learn how different running environments affect physiological responses, emotional regulation, exercise motivation, and attentional control in healthy college students.
- Trial name
- NCT07494552
- Testing
- Indoor Treadmill Running Session, Outdoor Road Running Session, Outdoor Grass Running Session
- Where
- China
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Sport
Obesity, Adolescent Obesity
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond…
- Conditions
- Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory
- Trial name
- PRESSURE (NCT06575738)
- Testing
- Injectable semaglutide or injectable tirzepatide, Standard postoperative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
ARDS, Sars-CoV-2 Infection
Physiological Response to Prone Position in COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS)
Retrospective study in COVID-19 ARDS patients hospitalised in the ICU. Investigators aim to explore the effects of prone positioning on oxygenation, dead space ventilation and mortality.
- Trial name
- NCT05092737
- Testing
- Prone positioning
- Where
- Switzerland
- Volunteers
- 31 people
- Sponsor
- University of Lausanne Hospitals
Overweight and Obese Adults, High Intensity Interval Exercise (HIIE)
Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity
Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases.
- Trial name
- COMEFIT (NCT06868862)
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Athletic Performance Enhancement
Effects of Blood Flow Restriction Training on Physical Function, Muscle Adaptations, and Performance in Roller Skaters
This randomized controlled trial evaluates the effects of adding blood flow restriction training to regular roller skating training on neuromuscular function under non-fatigued and fatigued conditions, muscle morphology, body…
- Trial name
- NCT07736157
- Testing
- Blood Flow Restriction Roller Skating Training, Standardized Roller Skating Training
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Sport
Healthy
Physiologic Performance Response to Salbutamol
This project aims to investigate the individual physiological response to beta2-adrenergic stimulation with salbutamol on performance-related outcomes
- Trial name
- NCT04615611
- Testing
- salbutamol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Physiological and Psychological Responses to Exercise
Effects of a Warm-up on Immune Response to Exercise
This randomized cross-over study compares two identical cardiorespiratory exercise bouts, differing only in the inclusion or exclusion of a dynamic period of increasing exercise intensity prior to the exercise bout.
- Trial name
- NCT04868136
- Testing
- Exercise
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Houston
Normal Physiological Response to Sweet Drinks
Brain and Glycemic Responses to Sweet Soft Drinks
The goal of this observational study is to determine changes in brain activity and blood sugar in response to the ingestion of flavored waters sweetened with either the nutritive sugar sucrose or different low-caloric sweeteners…
- Trial name
- SWEETBRAIN (NCT05575687)
- Testing
- Water (reference), Sucrose, Sucralose
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Critical Illness, Sepsis
Physiological Effects of 38°C vs. 22°C Fluid Therapy in Critically Ill Patients
A randomized controlled clinical trial. 24 adult ICU patients will be recruited upon decision to administer fluid bolus of 500ml of crystalloid.
- Conditions
- Critical Illness, Sepsis, Fluid Overload, Hemodynamic Instability
- Trial name
- NCT04576806
- Testing
- Body temperature, Fluid bolus, Room temperature
- Where
- 2 sites in Sweden
- Sponsor
- Karolinska Institutet
Neuromuscular Function, Athletic Performance Enhancement
Effects of Blood Flow Restriction Training on Neuromuscular Function and Performance in Artistic Jump Rope Athletes
The goal of this randomized controlled trial is to investigate whether blood flow restriction training can improve physical function and sports performance in artistic jump rope athletes.
- Trial name
- NCT07750977
- Testing
- Blood Flow Restriction Training, Conventional Artistic Jump Rope Training
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Sport
Exercise, Fatigue
Physiological Responses to Basketball-Specific Interval Exercise in Female Basketball Players
This study aims to evaluate the effects of interval exercise on metabolic and inflammatory responses, energy substrate utilization, and fatigue in trained female basketball players.
- Conditions
- Exercise, Fatigue, Sport Physiology
- Trial name
- INTER-BASKET (NCT07752459)
- Testing
- Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1)
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Eating Behavior
The Effect of Macronutrients on Satiety and Gut Hormone Responses
This study is part of a research theme aiming at elucidating the physiological mechanisms of action of weight loss after gastric bypass surgery.
- Trial name
- Microcapsule (NCT03466047)
- Testing
- Protein stomach, Protein distal small intestine, CHO stomach
- Where
- Ireland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy Nutrition
Study of the Neurophysiological Response to Foodstuffs
The goal of this clinical trial is to investigate the effect of perception of sensory attributes of different foodstuffs on physiological and neurophysiological response in health adults.
- Trial name
- NCT06051175
- Testing
- Bitter taste perception, Salty taste perception, Sweet taste perception
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Heat Acclimation and Thermotolerance, Heat Effect
Exercise in Extreme Hot Weather Conditions
Background: Core body temperature increases in hot climates due to exercise workload, disrupting heat gain and loss of balance. The human thermoregulatory system regulates core body temperature through factors such as metabolic…
- Trial name
- EXHOTCON (NCT07307391)
- Testing
- hot wet high (HWH), hot dry high (HDH), Experimental: hot dry low (HWL)
- Where
- Spain
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Response to Severe Stress
Effect of Tyrosine on Behavioral, Physiological and Nutritional Status During Survive, Evade, Resist, Escape (SERE) School
The objective of the proposed research is to determine if tyrosine, an amino acid found in protein-containing foods, will mitigate the cognitive deficits and adverse effects on behavior and mood produced by exposure to military…
- Trial name
- NCT01823276
- Testing
- Tyrosine-Containing Bar
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Safety Markers of Adjuvanted Influenza Vaccine
Placebo Controlled Study to Generate Data Characterising Clinical Events, Physiological Responses and Immune Responses
The purpose of this protocol is to generate a set of data that will be analysed by integrated systems biology approach, for validation in subsequent clinical trials or in animal models.
- Trial name
- NCT02523287
- Testing
- Fluad, Saline
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent