Clinical trials: Physiological Responses
Physiological Responses
The Role of TRP Channels in DPN
The study aims to characterize the vascular response upon topical application of cinnamaldehyde, allyl isothiocyanate and capsaicin on feet skin in healthy volunteers.
- Trial name
- NCT07237022
- Testing
- Cinnamaldehyde, Allyl isothiocyanate (AITC), Capsaicin
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Other Conditions That May Be A Focus of Clinical Attention
Chronic Sleep Restriction
Sleep is a physiological state considered essential for health and human survival. The prevalence of chronic sleep restriction has increased in modern society, as well as the effects of the same health concerns about various…
- Trial name
- CSR (NCT01493661)
- Testing
- Chronic Sleep Restriction
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Obesity, Sweeteners
Mapping the 'Sweet Brain' in Healthy Participants
The human brain has a central role in regulating appetite and food intake. It integrates many metabolic, hedonic and trait-related signals that affect eating behaviour and determine when and how much we eat.
- Trial name
- NCT04162457
- Testing
- Stevia, Glucose, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Dental Anxiety, Third Molar Extraction Surgery
Effect of Aromatherapy and Music Therapy on Physiological Response and Pain During Mandibular Third Molar Extraction
The goal of this clinical trial is to compare the effects of aromatherapy and music therapy on physiological responses and intraoperative pain in patients with moderate to severe dental anxiety undergoing mandibular third molar…
- Trial name
- AROMUSIC-M3 (NCT07647419)
- Testing
- Aromatherapy, Music Therapy
- Where
- Peru
- Volunteers
- 102 people
- Sponsor
- Universidad Científica del Sur
Sleep Deprivation
Combined Effects of Acute Sleep Restriction and Moderate Acceleration (+Gz) on Physiological and Behavioral Responses to High Mental Workload
Fighter pilots have to perform tasks requiring high mental workload during moderate-intensity acceleration phases (2 to 3G) that can last several minutes.
- Trial name
- CogPhyAero (NCT06017882)
- Testing
- Partial sleep deprivation
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Healthy
Physiological Response to 5 Days Fasting
To investigate energy metabolism, anthropometry, blood pressure, gut microbiome, serum metabolome, glucose variability and neural mechanisms of food choice and mood before and after 5 days of fasting as well as their persistence…
- Trial name
- NCT04452916
- Testing
- Buchinger fasting
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Heat Strain, Healthy Volunteer Study
The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response
The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers.
- Conditions
- Heat Strain, Healthy Volunteer Study, Kidney Dysfunction
- Trial name
- NCT06983730
- Testing
- Vitamin B3
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
COPD
Placebo Controlled Evaluation of Sedation and Physiological Response to Intranasal Dexmedetomidine in Severe COPD
A variety of medications have been used to treat the anxiety, discomfort, and fear associated with continuous and sudden episodic breathlessness in patients with advanced respiratory disease.
- Trial name
- NCT02773797
- Testing
- IN-DEX 1.0 mcg/kg, intranasal saline, IN-DEX 1.5 mcg/kg, intranasal saline
- Where
- United States
- Sponsor
- Dayton VA Medical Center
Physiological Stress
Impact of Breathing Interventions on Stress Markers
The goal of this clinical trial is to examine the effects of slow breathing breathing on markers of stress in healthy college aged individuals.
- Trial name
- NCT05825846
- Testing
- Virtual- reality active shooter drill
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas State University
Self Perception
Perception of Nonverbal Acoustic Signals and Resulting Physiological Responses (SINOVE-PER)
Like many other animals, humans produce nonverbal signals including screams, grunts, roars, cries and laughter across a variety of contexts.Due to their acoustic structure, nonverbal vocalizations and valanced speech (e.g.…
- Trial name
- SINOVE-PER (NCT05252312)
- Testing
- Psycho-acoustic tests
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Exercise, Cardiovascular Function, Fatigue, Muscular Power
Physiological Responses to Maximal 4-s Sprint Interval Cycling
The optimal recovery duration depends on the intensity of exercise and in the present study the intensity was maximal power for 4-s while cycling an 'Inertial Load' ergometer (ILE).
- Trial name
- NCT04448925
- Testing
- inertial-load exercise (ILE)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Depression
Physiologic Monitoring of Antidepressant Treatment Response
Study Objectives: to identify neurophysiologic effects of venlafaxine treatment in normal controls using quantitative EEG (QEEG) cordance to examine the effects of venlafaxine on different rating scales measuring mood and anxiety…
- Trial name
- Ven Nls I (NCT00759317)
- Testing
- venlafaxine (Effexor)
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autonomic Nervous System Function, Psychophysiological Regulation
Effects of Brief Heart Rate Variability Biofeedback on Physiological and Emotional Responses
This completed randomized laboratory study investigated the immediate effects of a single 10-minute session of heart rate variability biofeedback (HRV-B) on cardiac activity, forehead physiological signals, and emotional…
- Trial name
- NCT07911215
- Testing
- Psychoeducational Video Viewing, Heart Rate Variability Biofeedback
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Coronary Artery Disease, Postoperative Care
CABG-AI-Supported Discharge Education
This randomized controlled trial will evaluate the effectiveness of artificial intelligence-supported individualized discharge education for patients undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Artery Disease, Postoperative Care, Patient Discharge, Recovery of Function
- Trial name
- AI-D-E-CABG (NCT07503678)
- Testing
- AI-Supported Individualized Discharge Education, Standard Discharge Education
- Volunteers
- 128 people
- Sponsor
- Hasan Kalyoncu University
Personalized Nutrition
N=1 Trials of Individual Variability in Post-prandial Glycemic Responses to Diets of Varying Macronutrient Composition
The key objective of this study is to identify the most suitable diet (i.e. high protein, high fat, low GI, high GI) for an individual.
- Trial name
- NCT05402085
- Testing
- High Protein Diet, High Fat Diet, High Carbohydrate-Low Glycemic Index Diet
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Major Depression
Physiologic Monitoring of Antidepressant Response
Primary: to identify physiologic indicators of venlafaxine treatment response using quantitative EEG (QEEG) cordance, and to determine if cordance changes are specifically associated with response to venlafaxine; Secondary: to…
- Trial name
- NCT00792168
- Testing
- venlafaxine (Effexor)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of California, Los Angeles
Anxiety
Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response
The proposed study aims to investigate experimentally anxiety sensitivity and physiologic sensations associated with anxiety using a paradigm combining hydrocortisone, caffeine, and a set of social stress challenges.
- Trial name
- NCT02372110
- Testing
- HPA, ANS stimulation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Emotional, Affective, and Physiological Responses to Audiovisual Artworks Inspired by Climate-Related Environmental Changes in Nunavik
Emotional and Affective Responses to Music Inspired by Permafrost Thaw in Nunavik
This study will compare how young adults respond to four audiovisual artworks inspired by ice melt and permafrost thaw in Nunavik, northern Quebec. Permafrost is ground that remains frozen for at least two consecutive years.
- Trial name
- NCT07915089
- Testing
- Viewing Four Audiovisual Artworks Inspired by Environmental Changes in Nunavik
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal
Impacted Mandibular Third Molar Extraction, Dental Anxiety
Effects of Preoperative Information Formats in Third Molar Surgery
This study evaluates whether physician-guided visual information provided before impacted mandibular third molar surgery can improve hemodynamic stability during the perioperative period.
- Trial name
- NCT07484334
- Testing
- Standard Verbal Information, Real Surgical Video Information, 3D Animation Video Information
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Recep Tayyip Erdogan University
Tuberculosis
Effectiveness of Music Therapy
Tuberculosis belongs to chronic diseases as a result of the treatment of disease over a long period, admission to negative pressure isolation wards, and restrictions on visitors.
- Trial name
- TMT (NCT01040611)
- Testing
- Music therapy
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- Taipei Medical University WanFang Hospital