Clinical trials: Physiological Responses
Autism Spectrum Disorder
Evaluation of Behavioural Psycho & Physiological Responses in People With ASD During a Blood Test in Routine Care Practice
The project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test…
- Trial name
- AUTICOPP (NCT04638452)
- Testing
- Video & movements recording, Questionnaires
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Monitoring, Physiologic, Vital Signs
Bodytrak® Feasibility Study
Bodytrak® is a wireless earpiece which can monitor the user's vital signs such as tympanic (ear) temperature and heart rate. The earpiece is non-invasive and should fit comfortably within the right ear, similar to an earphone…
- Conditions
- Monitoring, Physiologic, Vital Signs, Sepsis, Altered Level of Consciousness
- Trial name
- NCT03139955
- Testing
- Bodytrak
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Inova Design Solutions Ltd
Heat Stress, Physiological Stress
Impact of Indoor Overheating on Physiological Strain in Children
Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children.
- Conditions
- Heat Stress, Physiological Stress, Cognitive Change
- Trial name
- NCT07261202
- Testing
- Simulated exposure to indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Septic Shock, Hyperlactatemia
Early Goal Directed Therapy Using a Physiological Holistic View. The ANDROMEDA-SHOCK Study
Septic shock is a highly lethal condition associated with a mortality risk of 30 to 60%. Optimizing tissue perfusion and oxygenation is the aim to decrease mortality and morbidity in septic shock patients.
- Conditions
- Septic Shock, Hyperlactatemia, Peripheral Perfusion
- Trial name
- ANDROMEDA (NCT03078712)
- Testing
- Peripheral Perfusion guided resuscitation, Lactate guided resuscitation
- Where
- Chile
- Volunteers
- 424 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Major Depressive Disorder
Stress Dynamics and Familial Risk for Depression in Female Adolescents
Stress and a parental history of major depressive disorder (MDD) are among the strongest risk factors for future development of MDD.
- Trial name
- NCT06816329
- Testing
- Computer Task Manipulation
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Residential Characteristics, Emotions
Adolescent Responses to Varying Environments in Virtual Reality Simulations
The objective of this study, named THRIVE (The Research In Virtual Environments Study), is to test hypotheses for how neighborhood environments influence stress and emotion, as a mechanism by which they may influence health.
- Conditions
- Residential Characteristics, Emotions, Stress, Psychological, Stress, Physiological
- Trial name
- NCT04465240
- Testing
- Virtual reality
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Exercise Adaptations
Role of Intermittent Exogenous Ketosis in the Physiological and Muscular Adaptive Response to Endurance Training
In a recent study (Poffé et al., 2019), we demonstrated that increasing the concentration of ketone bodies in the blood through the ingestion of a ketone ester (KE) post-exercise and just before sleeping time during a 3-week…
- Trial name
- NCT05932420
- Testing
- Ketone ester
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy Young Adults
Physiological Responses to Osteopathic Manipulative Techniques in Healthy Young Adults
This study was designed to investigate the effect of selected osteopathic manipulative techniques (OMT) on cardiovascular functions in healthy young men and women.
- Trial name
- NCT05515926
- Testing
- Cranial manipulation group, or cranial osteopathic techniques (OMM)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Touro University Nevada
Psoriasis, Metabolic Syndrome
Response of Metabolic Syndrome and Sexual Dysfunction to Lifestyle Changes in Men With Psoriasis
complaint of sexual dysfunction and metabolic syndrome are highly reported in men with psoriasis
- Conditions
- Psoriasis, Metabolic Syndrome, Erectile Dysfunction
- Trial name
- NCT05632042
- Testing
- lifestyle modification (exercise and control of diet)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pain, Chronic
Intradural Percutaneous Stimulation
The purpose of the study is to test the effects of intradural, spinal cord stimulation using a device placed in the same manner as a lumbar drain performed during a standard epidural spinal cord stimulation (SCS) trial routinely…
- Trial name
- NCT03380104
- Testing
- Intradural Spinal Cord Stimulation, Administration of Questionnaires
- Where
- United States
- Sponsor
- Matthew Howard
Sepsis
MEWS, qSOFA and Physiological Parameters Combination in the Emergency Room
In the development of sepsis treatment of recent years, the demand for medical manpower has increased significantly when patients with sepsis appear because of the expansion of medical care demand and shortened response time…
- Trial name
- qSOFA (NCT05584098)
- Testing
- qSOFA, MEWS and physiological parameters combination
- Where
- 2 sites in Taiwan
- Volunteers
- 950 people
- Sponsor
- St. Martin De Porress Hospital
Pain Management, Fear and Anxiety
Virtual Reality for Pain, Fear, and Physiological Responses During Pediatric Venous Catheterization
This study aims to evaluate the effect of two different virtual reality (VR) applications on children's pain, fear, and physiological parameters during peripheral intravenous catheterization.
- Trial name
- VR-PainKids (NCT07202468)
- Testing
- Virtual Reality
- Volunteers
- 150 people
- Sponsor
- Ege University
Hormone Disturbance, Stress Reaction
Stress Response in Emergency Among Physicians in Helicopter and Ambulance Based Emergency Medical Systems
Stress reactions in emergency physicians will be measures using cortol-awakening-reaction, heart-rate-variability and standardised stress questionnaires
- Conditions
- Hormone Disturbance, Stress Reaction, Stress Related Disorder
- Trial name
- NCT03422952
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Fasting, Metabolic Disturbance
Physiological and Sensory Responses to Prolonged Fasting in Humans
This study aims to establish the metabolic/molecular response in both adipose tissue and skeletal muscle as well as sensory experiences (pain, fatigue, drive) to prolonged fasting of 3 days duration.
- Conditions
- Fasting, Metabolic Disturbance, Energy Supply; Deficiency, Adiposity
- Trial name
- PRO-FAST (NCT05977569)
- Testing
- Prolonged Fasting
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Bath
Shock, Septic
Pilot Study: Echocardiographic and Hemodynamic Effects of Esmolol in Septic Shock Patients
After initial hemodynamic stabilization, 36 septic shock patients with heart rate > of 90 bpm and requiring norepinephrine to maintain mean arterial pressure (MAP) more than 65 mmHg will be randomised into two groups, esmolol…
- Trial name
- NCT02842983
- Testing
- Esmolol
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Peking Union Medical College Hospital
Healthy, Habitual; Drinking
The Influence of Fluid Intake on Daily Biological Rhythm and Mental Performance in Healthy Young Adults
Chronic low water intake may raise the risk of morbidity and mortality by influencing key water regulating hormones (e.g., AVP), which are known to modulate glucoregulation and renal function.
- Conditions
- Healthy, Habitual; Drinking, Stress, Physiological, Stress, Psychological
- Trial name
- NCT05491122
- Testing
- Increasing or decreasing daily total fluid intake
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Pulmonary Arterial Hypertension
Myocardial Metabolic Flux in Pulmonary Arterial Hypertension
The rationale for this study is that GLP-1 agonist treatment is likely to influence myocardial substrate utilisation, changing the predominant source of metabolic energy within the heart to a more energetically efficient form.
- Trial name
- NCT07737522
- Testing
- GLP-1 agonist
- Volunteers
- 32 people
- Sponsor
- Imperial College London
Erectile Dysfunction With Diabetes Mellitus
Genetic Factors of Erectile Dysfunction Degree and Response to Tadalafil Treatment in Patients With Diabetes
The goal of this clinical trial is to examine the genetic markers of erectile dysfunction degree in patients with diabetes and find new predictive models based on genetic factors, with which we will be able to more accurately…
- Trial name
- EDGEN (NCT06520839)
- Testing
- Tadalafil 5mg
- Where
- Slovenia
- Volunteers
- 90 people
- Sponsor
- University Medical Centre Ljubljana
Physical Activity
Effect of Energy Drink on Sport Performance and Psycho-Physiological Responses.
This work aimed to examine the effects of drinking an "energy drink" upon (i) short-term maximal performance, (ii) reaction times and (iii) psychological factors (i.e., mood state, ratings of perceived exertion (RPE) and…
- Trial name
- NCT03936712
- Testing
- Energy Drink
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Head Pain
Copeptin for Risk Stratification in Non-traumatic Headache in the Emergency Setting - The CoHead Study
Headache is a common symptom, and patients often seek medical attention at emergency departments due to headaches. The aim of the CoHead Study is to find out if it is possible by measuring copeptin, a marker of stress in the…
- Trial name
- CoHead (NCT01174901)
- Where
- 2 sites in Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland