Clinical trials: Pigmentation
Tattoo; Pigmentation, Melasma
Lutronic PicoPlus Exploratory Clinical Trial
This study will evaluate the use of the Lutronic PicoPlus for treatment of dermatological conditions such as unwanted tattoos and benign pigmented lesions.
- Conditions
- Tattoo; Pigmentation, Melasma, Benign Pigmented Lesion
- Trial name
- NCT03415685
- Testing
- PicoPlus laser system
- Where
- 4 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Acne, Acne Scars - Mixed Atrophic and Hypertrophic
AVAVA MIRIA General Use
A general protocol to treat a variety of dermatologic conditions and collect patient feedback. Primary outcome is the collection and analysis of patient questionnaires related to the overall experience of the device treatment.
- Conditions
- Acne, Acne Scars - Mixed Atrophic and Hypertrophic, Scars, Wrinkle
- Trial name
- NCT06868615
- Testing
- AVAVA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Healthy
Clinical Study for the Evaluation of the Depigmenting Activity of a Cosmetic Product on Spotted Hand Skin
Aim of the study was to evaluate by instrumental measurements the depigmenting activity of a cosmetic treatment for spotted hand skin; in particular it was investigated the synergic activity of an emulsion, with…
- Trial name
- NCT02204436
- Testing
- Emulsion and gel
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Derming SRL
VITILIGO
Response to Tregs in Innate Immunity Receptor LRP1 (CD91) and Tregs in Periferic Blood Mononuclear Cells in Patients With Non-segmentary Vitiligo
This study aims to evaluate some differences in the immune system between patients with vitiligo and patients without the disease.
- Trial name
- NCT03249064
- Testing
- CD 91 levels, Tregs
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Wrinkles in Decolletage, Pigmentation
A Study Assessing KB304 for the Treatment of Wrinkles in Women
The aim of this study is to investigate the safety and efficacy of KB304, an investigational gene therapy to correct moderate to severe wrinkles in the décolleté region (V-shaped chest area).
- Conditions
- Wrinkles in Decolletage, Pigmentation, Décolleté Wrinkles
- Trial name
- Pearl-2 (NCT06724900)
- Testing
- KB304, 0.9% Normal Saline (NS)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Krystal Biotech, Inc.
Melasma
Comparison of Intradermal Microinjections of Tanexamic Acid and Oral Tranexamic Acid in the Management of Melasma.
In this study we compared the effect of intradermal microinjections of tranexamic acid vs oral tranexamic acid in treatment of melasma.
- Trial name
- NCT07280234
- Testing
- Intradermal microinjections of tranexamic acid, Oral tranexamic acid
- Where
- Pakistan
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Acne Vulgaris, Post Inflammatory Hyperpigmentation
The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color
This is a single-center, open label pilot study. The study is comprised of 5 study visits; Screening, Baseline, and Weeks 4, 8, and 16.
- Trial name
- NCT03402893
- Testing
- ONEXTON Topical Gel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Vitiligo
Efficacy of 311-nm Ti:Sapphire Laser Versus 308-nm Excimer Laser Treatment in Vitiligo
A randomized controlled non-inferiority trial based on split-body was planned to compare the efficacy of 308-nm excimer laser and 311-nm Ti:Sapphire laser in patients with vitiligo.
- Trial name
- NCT02925767
- Testing
- 311-nm Ti:Sapphire laser, 308-nm excimer laser
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Inherited Retinal Dystrophy Primarily Involving Sensory Retina, Inherited Retinal Dystrophy Primarily Involving Retinal Pigment Epithelium
Establishment of the National Registry for Inherited Retinal Dystrophy in Iran
Purpose: To establish of the national Inherited Retinal Dystrophy Registry (IRDR) in Iran. Methods: This study is a community-based participatory research that is approved by the Ministry of Health and Medical Education of Iran…
- Trial name
- NCT04131400
- Testing
- Visual Acuity Testing and Retinal Imaging
- Where
- Iran
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Melasma
Cysteamine Compared to Hydroquinone in Melasma
Melasma is an acquired pigmentary disorder of symmetrical hyperpigmentation appearing as variable darkness macules and patches over the forehead, cheeks, and chin, even sun-exposed areas of the body.
- Trial name
- NCT05969587
- Testing
- 5% cysteamine cream, hydroquinone cream group
- Where
- Taiwan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Pigmentation, Oxidative Stress
A Study to Evaluate the Ability of Sunscreen Products to Modulate the Effects of Deep UVA +/- HEV Blue Light Induced Pigmentation and Biomarkers of Cutaneous Oxidative Stress
To assess the level of sub pigmentation following an acute exposure to a Deep Ultraviolet A and high energy Blue Light wavelengths (380-420 nm).
- Trial name
- NCT07695753
- Testing
- Sunscreen application #1, Sunscreen application #2
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Sunscreening Agent
18613 - Sun Protection Factor Assay
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- SPF Assay (NCT02757014)
- Testing
- Coppertone (BAY987517)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bayer
Gingival Pigmentation
Effect of Oxidant Gel and Anti-oxidant Gel on Wound Healing After Gingival Depigmentation
To evaluate effect of Oxidant (Oxygen Releasing Oral Gel) with Coe-Pak versus Anti-oxidant (Nano-emulsion complex propolis and vitamin C gel) with Coe-Pak on wound healing, pain, patient satisfaction after gingival depigmentation
- Trial name
- NCT05837416
- Testing
- blue®m Gel, NBF GINGIVAL GEL®, COE-PAK™
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Glucose Intolerance
Prevalence of Carbohydrate Intolerance in Lean and Obese Children
The prevalence of obesity in children is reaching epidemic proportions. Excess adiposity is more than just a cosmetic problem, having substantial metabolic consequences.
- Conditions
- Obesity, Glucose Intolerance, Diabetes, Acanthosis Nigricans
- Trial name
- NCT00000112
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Sunscreening Agents
Sun Protection Factor Assay (SPF Assay 19008)
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- NCT02815202
- Testing
- BAY987517
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Bayer
Skin Pigment, Skin Red
Skin Efficacy Testing of Astrion Products
This project aims to conduct safety and efficacy tests on the skin for the ingestion of Astrion Vitality Capsules, containing A. membranaceus and C. Asiatica roots, and the topical application of Astrion Vitality Cream.
- Trial name
- NCT06657352
- Testing
- ACS Topical Treatment Group, Oral Treatment + Topical Treatment Group, ACS Oral Treatment Group
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
Vitiligo
Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo
The present study will aim to evaluate: 1. The presence of Hypoxia Inducible Factor in vitiligo patient 2. Defect of Autophagy Related Genes in vitiligo patient 3.
- Trial name
- NCT06410898
- Testing
- Punch Biopsy 5mm
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Sunscreening Agents
Sun Protection Factor Assay (SPF Assay 203/2016)
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- NCT02930798
- Testing
- BAY987516
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Bayer
Gingival Pigmentation
Nano Silver Effect in Rapid Wound Healing
Silver compounds have demonstrated a positive effect in most medical fields, including periodontal therapy, particularly in their nano-formulations.
- Trial name
- NCT07521176
- Testing
- Nano Silver Dressing, Non eugenol zinc oxide Dressing
- Where
- Syria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Damascus University
Melasma
Inflammation in Melasma: Study of Its Infiltrate and the Expression of Acute and Chronic Mediators
Melasma is an acquired hyperpigmentary disorder that commonly affects women from Asia and Latin-America.There is evidence of subclinical inflammation supported by diffuse spectrometry and by prominent inflammatory cells in…
- Trial name
- NCT01952379
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí