Clinical trials: Pigmentation
Skin Pigment
Fractionated 1927nm Laser for Diffuse Pigmentation and Actinic Changes.
This is a single-site, non-randomized, non-controlled study at UT Southwestern Medical Center at Dallas in the Department of Plastic Surgery designed to follow up to 30 qualified and consenting subjects receiving a fractionated…
- Trial name
- NCT05226104
- Testing
- MOXI
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Non Therapeutic Body Modification
Post Market Safety Study and Effectiveness With Evolence in Subjects With Skin Color Types IV-VI
Approximately 165 subjects with Fitzpatrick Skin Color Types IV, V, and VI and a moderate to deep wrinkle between the corner of the nose and the corner of the mouth, will be treated with EVOLENCE® (an approved collagen filler) to…
- Trial name
- NCT00891774
- Testing
- EVOLENCE®
- Where
- 11 sites in United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Lentigines
A Single-Center 2-Arm Study for Lentigines on the Hands
The purpose of this study is to evaluate the effectiveness and safety of two laser systems for improvement of lentigines on the hands.
- Trial name
- NCT02763072
- Testing
- Enlighten Laser, Excel V Laser
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Photoaging
Combination Versus Laser Treatment Only
Our objective is to determine the effects of (1) basic skin care regimen + "active" (Lytera 2.0) vs. (2) basic skin care regimen only, both groups combined with laser, on the appearance of skin tone and photo-aging on the face.
- Trial name
- NCT03661697
- Testing
- Laser Therapy, Basic Skin Care Regimen, Lytera
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Vitiligo, Depressive Episode
Mental Health Associations With Vitiligo
This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with…
- Conditions
- Vitiligo, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04953338
- Testing
- Exposure of mental health condtion of interest
- Where
- United Kingdom
- Volunteers
- 36,104 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Healthy
Effect of Skin Pigmentation and Race/Ethnicity Factors on the Accuracy of Masimo Pulse Oximeters
This study is designed to compare the accuracy of a noninvasive measurement of oxygen saturation compared to reference values obtained by a laboratory blood gas analyzer.
- Trial name
- NCT04889222
- Testing
- INVSENSOR00050, RD SET SpO2
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Tattoo; Pigmentation, Melasma
Lutronic PicoPlus Exploratory Clinical Trial
This study will evaluate the use of the Lutronic PicoPlus for treatment of dermatological conditions such as unwanted tattoos and benign pigmented lesions.
- Conditions
- Tattoo; Pigmentation, Melasma, Benign Pigmented Lesion
- Trial name
- NCT03415685
- Testing
- PicoPlus laser system
- Where
- 4 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Vitiligo
PHNA, Efficacy of Tretinoin Cream on Post-phototherapy Hyperpigmentation
A randomized controlled split-face pilot study was planned to investigate the preventive effect of tretinoin 0.05% cream on hyperpigmentation during phototherapy in patients with vitiligo.
- Trial name
- NCT03933774
- Testing
- Tretinoin 0.05% cream
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Hyperpigmentation
Fractionated 1927nm Laser for Hyperpigmentation in Fitzpatrick Skin Phototypes V and VI
The primary objective of this study is to assess the efficacy of 1927nm non-ablative fractionated laser therapy to treat hyperpigmentation in patients ages 18-75 with Fitzpatrick Skin Phototypes V and VI and explore an effective…
- Trial name
- NCT05493280
- Testing
- MOXI
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pigment Skin
Combining Broad Based Light (BBL), Fractionated 1927 (MOXI) and Dual Wavelength 2940/1470 (HALO)
This is a single-site, non-randomized, non-controlled study at UT Southwestern Medical Center at Dallas in the Department of Plastic Surgery.
- Trial name
- NCT06091215
- Testing
- Sciton Joule System
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Vision, Entoptic
Macular Pigment and Glare Disability
The purpose of this study is: I. To measure MP optical density (MPOD) in two groups (experimental and placebo) of 50 subjects each (N = 100), during an Lutein + Zeaxanthin supplementation period of 12 months. II.
- Trial name
- MP-GD (NCT00909090)
- Testing
- 12 mg Lutein + Zeaxanthin
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Acne Vulgaris, Post Inflammatory Hyperpigmentation
The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color
This is a single-center, open label pilot study. The study is comprised of 5 study visits; Screening, Baseline, and Weeks 4, 8, and 16.
- Trial name
- NCT03402893
- Testing
- ONEXTON Topical Gel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Hyperpigmentation
An 18-week Study to Evaluate a Test Product With a Marketed Prescription Product
The purpose of this study is to assess the efficacy (ability to produce a desired or intended result) of a topical product (applied to the skin) to improve skin lightness, skin condition and appearance (hyperpigmentation [dark…
- Trial name
- NCT07136766
- Testing
- Facial Toner
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Good Molecules, LLC
Vitiligo
Evaluating the Efficacy of the Melanocyte Keratinocyte Transplantation Procedure in the Treatment of Vitiligo
Vitiligo is a dermatologic disease characterized by depigmentation of the skin. While the loss of melanocytes observed in vitiligo is driven by the immune system, repigmentation of the skin that occurs during UV light treatment…
- Trial name
- NCT04374435
- Testing
- MKTP with Surgical blade, MKTP with Negative Pressure Instrument, Suction blister grafting without cell dissociation
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Obesity, Acanthosis Nigricans
Children's Healthy Living Community Randomized Trial
The goal is to build social/cultural, political/economic, and physical/built environments that will promote active play and intake of healthy food to prevent young child obesity in the Pacific Region.
- Conditions
- Obesity, Acanthosis Nigricans, Central Obesity
- Trial name
- CHL (NCT01881373)
- Testing
- CHL program, Delayed Optimized CHL program
- Where
- United States
- Volunteers
- 9,840 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Acute Kidney Injury
Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types
This study was a pilot, safety, and pharmacokinetic study of MB-102 versus iohexol and the use of the non-invasive optical renal function monitor (ORFM) device in normal and compromised renal function participants with different…
- Trial name
- NCT02772276
- Testing
- MB-102-- single dose of 4 µmol/kg, MB-102-- single dose of 130 mg, MB-102-single dose of 130 mg or 2 doses of 130 mg 12 hours apart
- Where
- 3 sites in United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Age Related Macular Degeneration
Retinal and Retinal Pigment Epithelium (RPE) Autoimmunity in Age-related Macular Degeneration (AMD)
The investigators hope to determine if "wet" AMD patients differ from patients with "dry" AMD or normal eyes in the production of anti-retinal pigment epithelium (anti-RPE) or anti-retinal antibody formation.
- Trial name
- Antibody (NCT00931489)
- Testing
- ranibizumab (Lucentis(R))
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Lawrence S. Morse, MD
Aging
The Effectiveness of Epidermal Growth Factor Serum in Improve Facial Skin Hydration, Elasticity, Pigmentation, and Wrinkles.
EGF is a polypeptide that promotes cell differentiation and collagen production while decreasing melanin production. This study is designed to study its effectiveness in improving the texture and appearance of facial skin after…
- Trial name
- NCT05724589
- Testing
- Epidermal Growth Factor
- Where
- Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Institute of Dermatology, Thailand
Healthy
Performance of Masimo MightySat Pulse Oximeter in Differing Levels of Skin Pigmentation
Evaluation of the noninvasive oxygen saturation (SpO2) performance of the noninvasive Masimo MightySat against reference arterial blood samples analyzed by a laboratory CO-oximeter reference instrument.
- Trial name
- NCT05083351
- Testing
- MightySat
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Solar Lentigines
A Fixed Triple Combination Cream for Solar Lentigines Associated to Cryotherapy
To evaluate safety and efficacy of Tri-Luma® cream as an adjunctive treatment to cryotherapy when used in the pre- and post-procedure phases for the treatment of solar lentigines on the back of the hands and in the prevention of…
- Trial name
- NCT01778179
- Testing
- Tri-luma, Cryotherapy (CRY-AC3® device)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic