Clinical trials: Pigmentation Disorder
Hypoxia, Skin Pigmentation
Pulse Oximeter Accuracy in Healthy Humans During Hypoxia
The aim of this project is to test the accuracy of pulse oximeters during mild, moderate and severe hypoxia. This is done by comparing the reading of the pulse oximeter during brief, steady state hypoxia with a gold-standard…
- Trial name
- NCT06142019
- Testing
- Controlled desaturation (hypoxemia)
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Skin Pigment, Pulse Oximetry
Neonatal Pulse Oximetry Disparities Due to Skin Pigmentation
The goal of this clinical trial is to determine if pulse oximeters show an SaO2-SpO2 discrepancy that correlates with skin pigmentation such that pulse oximetry will overestimate oxygenation in newborns with darker skin.
- Trial name
- Neo-PODS (NCT06063148)
- Testing
- Enrolled Participant
- Where
- 2 sites in United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Macular Pigmentation, Skin Pigment
Macular Pigment Measurements in Eye & Other Tissues
The purpose of this study is to understand the role of nutrition and its effects on the eye and other tissues. The investigators propose to study this by validating and correlating various non-invasive measurement methods of…
- Trial name
- NCT03022773
- Testing
- Carotenoid measurements
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Skin Pigmentation, Healthy Volunteers
Efficacy of Cosmetic Products in Preventing Pigmentation Induced by High Energy Visible Light (HEVL) [400-450nm]
The goal of this double-blind, randomized clinical trial is to evaluate the efficacy of anti-pigmentation cosmetic products in preventing skin pigmentation induced by High Energy Visible Light (HEVL) [400-450nm] in healthy…
- Conditions
- Skin Pigmentation, Healthy Volunteers, Hyperpigmentation
- Trial name
- NCT07537595
- Testing
- Treated and exposed zones (cosmetic topical products applied), Untreated and exposed zone (no product applied)
- Where
- Romania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Pigment Skin
Combining Broad Based Light (BBL), Fractionated 1927 (MOXI) and Dual Wavelength 2940/1470 (HALO)
This is a single-site, non-randomized, non-controlled study at UT Southwestern Medical Center at Dallas in the Department of Plastic Surgery.
- Trial name
- NCT06091215
- Testing
- Sciton Joule System
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Skin Pigmentation
Evaluation of a Tranexamoc Acid Treatment on Post-inflammatory Pigmentation in the Suction Blister Model
Post-inflammatory hyperpigmentation (PIH) is a common sequela of inflammatory dermatoses. PIH results from the overproduction of melanin or irregular pigment dispersion after skin inflammation.
- Trial name
- TRANEX (NCT05311033)
- Testing
- Exacyl
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Skin Diseases, Healthy Skin
An Observational Study to Assess Objective Skin Pigmentation Variation.
Accurate assessment of skin pigmentation is essential in dermatology for properly diagnosing and managing a wide range of skin conditions.
- Trial name
- SKIN-IMAGING (NCT07091604)
- Where
- Netherlands
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Skin Pigmentation, Photobiology
A Study to Evaluate the Cutaneous Effects of Deep Ultraviolet A +/- High-Energy Visible Blue Light Exposure
The objective of this study is to assess the level of pigmentation following an acute exposure of skin to light regimens representative of portions of the natural sunlight spectrum and that contain Deep UVA wavelengths with or…
- Trial name
- NCT06654102
- Testing
- Deep UVA Irradiation, Deep UVA+HEV Blue Light Irradiation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Skin Pigment, Skin Red
Skin Efficacy Testing of Astrion Products
This project aims to conduct safety and efficacy tests on the skin for the ingestion of Astrion Vitality Capsules, containing A. membranaceus and C. Asiatica roots, and the topical application of Astrion Vitality Cream.
- Trial name
- NCT06657352
- Testing
- ACS Topical Treatment Group, Oral Treatment + Topical Treatment Group, ACS Oral Treatment Group
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
Skin Pigmentation
Process Validation in Dermatology: Assessing Methods for UV Exposure (Artificial Source vs. Sunlight) and Efficacy Evaluation of Anti-Tanning Agents
The rationale of this study is to establish a robust method for assessing sun protection product efficacy in preventing erythema and tanning.
- Trial name
- NCT06384092
- Testing
- Test Sun Protection Cream, Benchmark Sun Protection Cream
- Where
- India
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Wrinkle, Pigment Skin
A Clinical Study to Assess the Safety and Effectiveness of Anti-Ageing and Skin Brightening Gel
This is a Randomized, Interventional, Prospective, Double Blind, Two Arm, Comparative, Parallel, Placebo-Controlled, Safety and Efficacy Study of Anti-Ageing and Skin Brightening Gel.
- Conditions
- Wrinkle, Pigment Skin, Aging
- Trial name
- NCT06123572
- Testing
- Anti-Ageing and Skin Brightening Gel
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Skin Pigment
Correlation Between Objective Skin Pigment Measurement and Fitzpatrick Skin Type
The purpose of this study is to correlate subjective skin pigment measurements as reported by patient-responses to the Fitzpatrick Skin Type Scale versus objective classification of skin pigment utilizing Individual Typology…
- Trial name
- NCT06144541
- Testing
- Survey administration for Fitzpatrick skin type, Measurement of ITA based on SkinColorCatch instrument
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Skin Pigment, Photoaging
A Single-Center Open-Label Study of 1064 nm for Nonablative Skin Rejuvenation
The purpose of this investigation is to evaluate the safety and efficacy of the Cutera excel V Laser Genesis procedure utilizing the 1064nm laser for skin rejuvenation.
- Trial name
- NCT03421691
- Testing
- excel V Laser
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Skin Pigment
Fractionated 1927nm Laser for Diffuse Pigmentation and Actinic Changes.
This is a single-site, non-randomized, non-controlled study at UT Southwestern Medical Center at Dallas in the Department of Plastic Surgery designed to follow up to 30 qualified and consenting subjects receiving a fractionated…
- Trial name
- NCT05226104
- Testing
- MOXI
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Wrinkle, Skin Pigmentation
Prospective Study of Topical Vitamin C (THDA) Versus Topical Vitamin C (THDA) With Acetyl Zingerone
The purpose of this study is to asses the impact of topically applying a form of vitamin C known as tetrahexyldecyl Ascorbate (THDA) along with a novel anti-aging ingredient, acetyl zingerone, compared against applying THDA alone.
- Trial name
- NCT05779280
- Testing
- THDA + Acetyl Zingerone Topical Product, THDA
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Pigmentation, Pigmentation Disorder
A Prospective, Split-face, Randomized Study of the Poly-D, L Lactic Acid (PDLLA) for Photoaged Skin
Juvelook® (VAIM, Korea) is made by dissolving irregular PDLLA particles in a solvent mixture of DMSO (Dimethylsulfoxide) and EC (Ethylene Carbonate) and then injecting them through microneedling to create reticulated foamy…
- Trial name
- NCT05913102
- Testing
- PDLLA
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jin Cheol Kim
Healthy, Wrinkle
Safety and Efficacy Study of Vasu Facial Beauty Oil
This is an open-label, single-arm, single-center, proof-of-concept, exploratory, safety and efficacy, clinical study of a Vasu Facial Beauty Oil in healthy adult human subjects.
- Conditions
- Healthy, Wrinkle, Dry Skin, Skin Pigment
- Trial name
- NCT05646953
- Testing
- Facial Beauty Oil
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Inflammation, Skin Abnormalities
Effects of Bend Beauty's Anti-Aging Formula on Inflammatory Markers
This is a phase IV, randomized, double-blind, placebo-controlled, three-arm, parallel intervention study including three groups of 25 subjects between 35-65 years of age, treated with either Bend Beauty's Anti-Aging Formula, fish…
- Conditions
- Inflammation, Skin Abnormalities, Skin Pigment, Inflammatory Response
- Trial name
- BENCHMARK (NCT03862872)
- Testing
- Anti-Aging Formula, Control Fish Oil
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bend Beauty Inc.
Skin Pigmentation, Free Radicals
EPR (Electron Paramagnetic Resonance) as Method of Non-invasive Characterization of Melanin Content in Skins With Different Phototypes
The aim of this study is to assess the signal of melanin using Electron Paramagnetic resonance (EPR). Melanin is a paramagnetic pigment detectable by EPR.
- Conditions
- Skin Pigmentation, Free Radicals, Phototype, Magnetic Resonance
- Trial name
- NCT04270903
- Testing
- EPR measurement
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Wrinkle Appearance, Skin Pigment
Cosmetic Effects of Topical Acetyl Zingerone
Cosmeceuticals are an emerging market within dermatology and the growth of natural products and derivatives of natural products has accelerated in use within the field.
- Conditions
- Wrinkle Appearance, Skin Pigment, Erythema, Side Effect
- Trial name
- NCT03530787
- Testing
- Acetyl Zingerone Topical Cream, Topical cream
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of California, Davis