Clinical trials: Pilonidal Disease
Pilonidal Sinus, Pilonidal Disease
The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children
Chronic wounds that fail to heal over extended periods pose a significant financial burden on the healthcare system, underscoring the urgent need to enhance clinical treatments.
- Trial name
- NCT06391307
- Testing
- Crystallized phenol, Crystallized phenol + Exosome, Crystallized phenol + Stem Cell
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Azizoğlu
Pilonidal Disease, Pilonidal Cyst
Feasibility of a Novel Technique for Pilonidal Wound Healing
Pilonidal disease (PD) is a chronic disease with a major impact on patient quality of life and productivity. Thus, wound healing would have a significant effect on patient quality outcomes, patient quality of life, and healthcare…
- Conditions
- Pilonidal Disease, Pilonidal Cyst, Pilonidal Sinus
- Trial name
- NCT02330159
- Testing
- Novel Wound Healing Protocol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Southeast Clinical Research Associates, Houston, Texas
Pilonidal Disease
Excision and Reconstruction of the Natal Cleft With a Parasacral Perforator Flap Versus Open Excision With Secondary Healing, in the Management of Sacrococcygeal Pilonidal Disease.
Chronic sacrococcygeal pilonidal disease is a common acquired condition associated with hirsutism that predominantly affects young male patients.
- Trial name
- PILOPERFO (NCT03534700)
- Testing
- parasacral flap reconstruction, open excision
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Toulouse
Pilonidal Sinus
Crystallized Phenol Versus Transposition Flaps for Treatment of Pilonidal Disease: A Prospective Study
Although surgical techniques such as limberg flap. modified limberg flap and karydakis are currently most popular treatment methods for pilonidal disease, crystallized phenol application is also successfully used for pilonidal…
- Trial name
- NCT01792557
- Testing
- Crystallized phenol, Limberg Flap, Modified Limberg Flap
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- S.B. Konya Education and Research Hospital
Pilonidal Disease
Comparison of Laser Destruction of Pilonidal Sinus Disease (SILAC) and Bascom II Procedure.
Surgical treatment witn lateralization of intergluteal cleft is still gold standard for pilonidal sinus disaease. But nowadays minimally invasive treatment methods such as the use of a diode laser (SiLac, Sinus Laser Closure) to…
- Trial name
- SI-BAS (NCT05715983)
- Testing
- Bascom II procedure, SiLaC
- Where
- Russia
- Volunteers
- 164 people
- Sponsor
- Russian Society of Colorectal Surgeons
Pilonidal Sinus
Pilonidal Sinus Disease
The aim of this study is to compare the outcomes of Karydakis technique versus sinus tract ablation procedure using 1470 nm Diode laser for the treatment of pilonidal sinus and provide evidence-based guidance to select the most…
- Trial name
- NCT06508086
- Testing
- laser ablation technique in the treatment of pilonidal sinus, Karydakis technique in the treatment of pilonidal sinus
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Pilonidal Disease
Debridement and Laser Ablation Versus Debridement Alone in Pilonidal Disease
This study aims to investigate the effect of laser ablation (LA) in minimally invasive management of pilonidal disease (PD). Data of the patients with PD who were eligible for simple debridement have been prospectively collected…
- Trial name
- NCT05569135
- Testing
- Laser ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Istanbul Medipol University Hospital
Pilonidal Sinus, Pilonidal Disease
Application of Platelet-rich Plasma in Pilonidal Sinus Disease
Pilonidal sinus disease is a common health-care problem, and surgical excision is the standard treatment modality. Controversy still exists regarding the best surgical technique for treating pilonidal disease in terms of…
- Conditions
- Pilonidal Sinus, Pilonidal Disease, Wound Heal, Quality of Life
- Trial name
- NCT04697082
- Testing
- Open surgery, Minimal invasive surgery, Platelet rich plasma administration
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Cihangir Akyol
Endoscopic Pilonidal Sinus
Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease
Aim of the work To compare lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing time and return to daily…
- Trial name
- NCT04418310
- Testing
- Lay open and curettage, Endoscopic (E.P.Si.T) method
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Pilonidal Sinus
Study on Surgical Treatment of Pilonidal Sinus Disease
Comparison of limited excision-primary closure, Limberg, and modified Limberg flap techniques for the surgical treatment of pilonidal sinus disease, each performed by a separate surgeon, in terms of postoperative outcomes and…
- Trial name
- NCT02849197
- Testing
- surgery for pilonidal sinus disease
- Volunteers
- 802 people
- Sponsor
- Bezmialem Vakif University
Pain, Acute Post-Operative, Pilonidal Sinus
Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery
Introduction: This study investigated the efficacy of sacral erector spinae plane block (ESPB) for managing postoperative pain and reducing opioid consumption in patients undergoing hemorrhoid and pilonidal sinus (PS) surgery.
- Conditions
- Pain, Acute Post-Operative, Pilonidal Sinus, Hemorrhoids, Anesthesia
- Trial name
- NCT06459739
- Testing
- sacral ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Pilonidal Disease, Recurrence
Unroofing Curettage for Pilonidal Disease
This study aimed to investigate the outcomes of patients who underwent UC as the primary intervention for simple or complex SPD
- Conditions
- Pilonidal Disease, Recurrence, Healing Wound
- Trial name
- NCT05339828
- Testing
- unroofing curettage
- Where
- Turkey (Türkiye)
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital
Pilonidal Disease
Pilot Study of Laser Hair Depilation for Pilonidal Disease
Pilot study to assess tolerability and safety of laser hair depilation in adolescents and young adults with pilonidal disease.
- Trial name
- NCT02778152
- Testing
- Laser depilation
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Peter Minneci
Pilonidal Disease, Recurrence
Comparison of Tension Free Primary Closure, Karydaks and Limberg Flap Methods
Pilonidal sinus is a chronic inflammatory disorder of intergluteal sulcus. The disease seen in between 15-35 years of age and 3-4 times more in males. The incidence of the disease is found as 8.8% in Turkish soldiers.
- Conditions
- Pilonidal Disease, Recurrence, Complication
- Trial name
- NCT02186964
- Testing
- tension free primary closure, karydakis, Limberg flap
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Konya Meram State Hospital
Pilonidal Disease
Open Wide Excision Versus Minimal Surgery for Pilonidal Disease
In order to compare the early recurrence rates of pilonidal disease and overall patient satisfaction between procedures involving minimal and wide open excisions, we propose to perform a prospective, randomized clinical trial…
- Trial name
- NCT01241136
- Testing
- open wide-excision pilonidal cystectomy, minimal invasive pilonidal cystotomy
- Where
- United States
- Sponsor
- United States Naval Medical Center, Portsmouth
Pilonidal Sinus
Minimally Invasive Treatment Methods for Pilonidal Disease
Patients with pilonidal sinus disease will be randomised to two groups (crystallised phenol and platelet rich plasma). Sinus healing time, patient satisfaction, complications and recurrence rates will be compared.
- Trial name
- NCT03070028
- Testing
- crystallised phenol, Platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Uşak University
Pilonidal Sinus
GLUtEus Maximus Fascia Plasty Flap for Pilonidal Sinus
Surgical treatment is still gold standard for pilonidal sinus disease. Several surgical techniques have been proposed to treat this disease in the last two decades.
- Trial name
- GLUE (NCT03914729)
- Testing
- Primary Closure, Gluteus Maximus Fascia Plasty Flap
- Where
- Russia
- Volunteers
- 84 people
- Sponsor
- Russian Society of Colorectal Surgeons
Sacrococcygeal Pilonidal Disease
Modified Limberg Procedure Versus Lateral Advancement Flap With Burrow's Triangle Procedure in the Treatment of Pilonidal Sinus
The investigators want to share our study that is the "Comparison of Modified Limberg Flap Transposition and Lateral Advancement Flap Transposition with Burrow's Triangle in the Surgical Treatment of Sacrococcygeal Pilonidal…
- Trial name
- NCT02116738
- Testing
- Flap Transposition Procedures
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ankara Mevki Military Hospital
Pilonidal Sinus
Umblical Pilonidal Sinus Evaluation
Purpose: Pilonidal sinus disease (PSD) is a chronic inflammatory condition of skin due to implanted loose hair. PSD is commonly seen in sacrococcygeal region, but can also be seen in axilla, perineum, suprapubic regions, on hands…
- Trial name
- NCT04856605
- Testing
- surgery
- Volunteers
- 82 people
- Sponsor
- Istanbul Medeniyet University
Pilonidal Sinus of Natal Cleft, Pilonidal Sinus Without Abscess
Crystallized Phenol Treatment in Pilonidal Sinus
Pilonidal sinus disease is an acquired disorder of the natal cleft and its incidence is reported as 6 in 100,000. Although there are many opinions regarding the treatment of pilonidal sinus disease in the literature, surgery is…
- Trial name
- NCT04681443
- Testing
- Crystallized phenol application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gulhane Training and Research Hospital