Clinical trials: Pilonidal Sinus
Pilonidal Sinus, Pilonidal Disease
The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children
Chronic wounds that fail to heal over extended periods pose a significant financial burden on the healthcare system, underscoring the urgent need to enhance clinical treatments.
- Trial name
- NCT06391307
- Testing
- Crystallized phenol, Crystallized phenol + Exosome, Crystallized phenol + Stem Cell
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Azizoğlu
Pilonidal Cyst and Sinus Without Abscess
Karydakis Versus Limberg Flap for the Management of Primary Sacrococcygeal Pilonidal Sinus
study comparing the Karydakis and Limberg flaps
- Trial name
- NCT07271537
- Testing
- karydakis surgery, Limberg flap
- Where
- Egypt
- Volunteers
- 352 people
- Sponsor
- Zagazig University
Pilonidal Disease, Pilonidal Cyst
Feasibility of a Novel Technique for Pilonidal Wound Healing
Pilonidal disease (PD) is a chronic disease with a major impact on patient quality of life and productivity. Thus, wound healing would have a significant effect on patient quality outcomes, patient quality of life, and healthcare…
- Conditions
- Pilonidal Disease, Pilonidal Cyst, Pilonidal Sinus
- Trial name
- NCT02330159
- Testing
- Novel Wound Healing Protocol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Southeast Clinical Research Associates, Houston, Texas
Chronic Sacrococcygeal Pilonidal Sinus
Video Assisted Ablation of Pilonidal Sinus Versus Conventional Treatment
Video assisted ablation of pilonidal sinus (VAAPS) is a new endoscopic minimally invasive treatment. In an attempt to validate the effectiveness of the VAAPS, the investigators have designed a comparative study between the…
- Trial name
- NCT02222298
- Testing
- Video assisted ablation of pilonidal sinus, Bascom Cleft lift procedure
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Pilonidal Sinus
Endoscopic Pilonidal Sinus Treatment (EPSIT) Versus Sinus Laser Closure (SiLaC) Versus Lay Open Technique
Aim of the work To compare Sinus Laser closure versus lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing…
- Trial name
- NCT04418336
- Testing
- Endoscopic Pilonidal sinus treatment (EPSIT) versus Sinus Laser Closure (SiLaC) versus lay open technique
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Pilonidal Sinus
Crystallized Phenol Versus Transposition Flaps for Treatment of Pilonidal Disease: A Prospective Study
Although surgical techniques such as limberg flap. modified limberg flap and karydakis are currently most popular treatment methods for pilonidal disease, crystallized phenol application is also successfully used for pilonidal…
- Trial name
- NCT01792557
- Testing
- Crystallized phenol, Limberg Flap, Modified Limberg Flap
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- S.B. Konya Education and Research Hospital
Pilonidal Disease
Comparison of Laser Destruction of Pilonidal Sinus Disease (SILAC) and Bascom II Procedure.
Surgical treatment witn lateralization of intergluteal cleft is still gold standard for pilonidal sinus disaease. But nowadays minimally invasive treatment methods such as the use of a diode laser (SiLac, Sinus Laser Closure) to…
- Trial name
- SI-BAS (NCT05715983)
- Testing
- Bascom II procedure, SiLaC
- Where
- Russia
- Volunteers
- 164 people
- Sponsor
- Russian Society of Colorectal Surgeons
Pilonidal Sinus
Pilonidal Sinus Disease
The aim of this study is to compare the outcomes of Karydakis technique versus sinus tract ablation procedure using 1470 nm Diode laser for the treatment of pilonidal sinus and provide evidence-based guidance to select the most…
- Trial name
- NCT06508086
- Testing
- laser ablation technique in the treatment of pilonidal sinus, Karydakis technique in the treatment of pilonidal sinus
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Pilonidal Sinus, Pilonidal Disease
Application of Platelet-rich Plasma in Pilonidal Sinus Disease
Pilonidal sinus disease is a common health-care problem, and surgical excision is the standard treatment modality. Controversy still exists regarding the best surgical technique for treating pilonidal disease in terms of…
- Conditions
- Pilonidal Sinus, Pilonidal Disease, Wound Heal, Quality of Life
- Trial name
- NCT04697082
- Testing
- Open surgery, Minimal invasive surgery, Platelet rich plasma administration
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Cihangir Akyol
Endoscopic Pilonidal Sinus
Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease
Aim of the work To compare lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing time and return to daily…
- Trial name
- NCT04418310
- Testing
- Lay open and curettage, Endoscopic (E.P.Si.T) method
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Pilonidal Sinus
Study on Surgical Treatment of Pilonidal Sinus Disease
Comparison of limited excision-primary closure, Limberg, and modified Limberg flap techniques for the surgical treatment of pilonidal sinus disease, each performed by a separate surgeon, in terms of postoperative outcomes and…
- Trial name
- NCT02849197
- Testing
- surgery for pilonidal sinus disease
- Volunteers
- 802 people
- Sponsor
- Bezmialem Vakif University
Pilonidal Sinus
Sacrococcygeal Local Anesthesia With Different Doses of Clonidine for Pilonidal Sinus Surgery
Sacrococcygeal local anesthesia was shown to reduce the time spent in the operating room as well as in the recovery room. In addition, decreased hospital stay and postoperative analgesic consumption.
- Trial name
- NCT02539693
- Testing
- Clonidine 75 µg/mL in sacrococcygeal block, Clonidine 150 µg/mL in sacrococcygeal block, Lidocaine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Pain, Acute Post-Operative, Pilonidal Sinus
Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery
Introduction: This study investigated the efficacy of sacral erector spinae plane block (ESPB) for managing postoperative pain and reducing opioid consumption in patients undergoing hemorrhoid and pilonidal sinus (PS) surgery.
- Conditions
- Pain, Acute Post-Operative, Pilonidal Sinus, Hemorrhoids, Anesthesia
- Trial name
- NCT06459739
- Testing
- sacral ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Pilonidal Sinus
Combined Open and Closed Approach for Management of Pilonidal Sinus by Special U-shaped Sutures Without Drain.
Introduction: Pilonidal sinus disease (PSD) is a common surgical disease frequently seen in the intergluteal cleft. The treatment of this problem is mainly surgical.
- Trial name
- NCT04017260
- Testing
- open and closed approach, Rhomboid flap technique, Karydakis technique
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pilonidal Sinus
Pilonidal Excision Versus Endoscopic Surgery
Compare clinical outcomes of endoscopic pilonidal sinus treatment (EPSiT) with excision treatment with a randomised clinical trial.
- Trial name
- PEVES (NCT03923621)
- Testing
- EPSiT, Excision
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St Helens & Knowsley Teaching Hospitals NHS Trust
Pilonidal Disease, Recurrence
Comparison of Tension Free Primary Closure, Karydaks and Limberg Flap Methods
Pilonidal sinus is a chronic inflammatory disorder of intergluteal sulcus. The disease seen in between 15-35 years of age and 3-4 times more in males. The incidence of the disease is found as 8.8% in Turkish soldiers.
- Conditions
- Pilonidal Disease, Recurrence, Complication
- Trial name
- NCT02186964
- Testing
- tension free primary closure, karydakis, Limberg flap
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Konya Meram State Hospital
Pilonidal Sinus
Video Assisted Ablation of Pilonidal Sinus
The investigators supposed that the complete video assisted ablation of pilonidal sinus (VAAPS) could be an effective minimally invasive treatment of pilonidal sinus.
- Trial name
- NCT01963273
- Testing
- Video Assisted Ablation of Pilonidal Sinus
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Pilonidal Sinus, Pilonidal Cyst
Karydakis Procedure Versus Excision With Healing by Secondary Intention (EHSI) in Sacrococcygeal Pilonidal Sinus
Recurrence, Complications, Work-off date, Healing time and Patients Willingness in Karydakis Technique for Treatment of Sacrococcygeal Pilonidal Sinus versus Healing by Secondary Intention (EHSI) Technique in Imam Khomeini…
- Trial name
- NCT00716937
- Testing
- karydakis flap, laying open
- Where
- Iran
- Volunteers
- 321 people
- Sponsor
- Tehran University of Medical Sciences
Pilonidal Sinus
Minimally Invasive Treatment Methods for Pilonidal Disease
Patients with pilonidal sinus disease will be randomised to two groups (crystallised phenol and platelet rich plasma). Sinus healing time, patient satisfaction, complications and recurrence rates will be compared.
- Trial name
- NCT03070028
- Testing
- crystallised phenol, Platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Uşak University
Pilonidal Sinus
GLUtEus Maximus Fascia Plasty Flap for Pilonidal Sinus
Surgical treatment is still gold standard for pilonidal sinus disease. Several surgical techniques have been proposed to treat this disease in the last two decades.
- Trial name
- GLUE (NCT03914729)
- Testing
- Primary Closure, Gluteus Maximus Fascia Plasty Flap
- Where
- Russia
- Volunteers
- 84 people
- Sponsor
- Russian Society of Colorectal Surgeons