Clinical trials: Pilonidal Sinus, open to volunteers
Sacrococcygeal Pilonidal Sinus
Effectiveness of Different Surgical Techniques for Curative Treatment of Pilonidal Sinus Disease in the Pediatric Population
Pilonidal sinus disease (PSD) in children is associated with significant morbidity and recurrence risk. Multiple surgical techniques are used, including excision with open healing, primary midline closure, off-midline closure…
- Trial name
- PiloPedia (NCT07470294)
- Testing
- Surgical treatment for pilonidal sinus disease, including various techniques including excision with or without primary closure, or endoscopic techniques.
- Volunteers
- 90 people
- Sponsor
- University Hospital, Angers
Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease
The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus
"Assessment of postoperative pain with conventional and tumescent local anesthesia in the laser treatment of pilonidal sinus." The aim of this study is to: examine the possible difference in postoperative pain between two local…
- Conditions
- Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease, Pilonidal Sinus Treatment, Laser Ablation
- Trial name
- NCT07408414
- Testing
- local anesthesia using 2% lidocaine, SiLaC, Questionnaire and physical examination
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Opća županijska bolnica Požega
Pilonidal Sinus Disease, Pilonidal Sinus Treatment
Teach-Back Discharge Education After Pilonidal Sinus Surgery
This randomized controlled trial will evaluate the effect of Teach-Back-supported discharge education on self-care agency, pain intensity, and comfort levels in patients undergoing surgery for pilonidal sinus disease.
- Trial name
- TB-PSS (NCT07851285)
- Testing
- Teach-Back-Supported Discharge Education, Routine Discharge Education
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Halic University
Tissue Repair, Soft Tissue Reconstruction
Urinary Bladder Matrix (UBM) Registry
The purpose of this registry is to collect real-world information on patients treated with Urinary Bladder Matrix (UBM) products.
- Conditions
- Tissue Repair, Soft Tissue Reconstruction, Wound Management, Pressure Ulcer (PU)
- Trial name
- NCT07805798
- Testing
- Urinary Bladder Matrix (UBM) Products
- Volunteers
- 300 people
- Sponsor
- Integra LifeSciences Corporation
Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess
SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study.
Pilonidal sinus disease (PSD) is a chronic inflammatory condition of the sacrococcygeal region that frequently affects young adults, often causing pain, drainage, and recurrent infection.
- Conditions
- Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess, Pilonidal Sinus, Pilonidal Cysts
- Trial name
- SiLaC-LaPaz (NCT07260643)
- Testing
- SilaC
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario La Paz
Pilonidal Sinus, Wound Healing
ENVELOP: Wound Care Following Pilonidal Sinus Surgery
This is a single-blinded, multicentre, prospective randomised controlled trial (RCT) comparing post-operative and patient-reported outcomes for patients undergoing application of negative-pressure wound therapy (NPWT) after sinus…
- Trial name
- ENVELOP (NCT06647290)
- Testing
- Negative Pressure Wound Therapy, Standard wound care
- Where
- 10 sites in Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland
Pilonidal Disease
Intraoperative Wound Irrigation for Pilonidal Disease
The purpose of this study is to determine the best method for cleaning wounds during surgery for patients with Stage 3 pilonidal disease.
- Trial name
- NCT07417202
- Testing
- Hypochlorous Acid
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Stanford University
Pilonidal Disease, Pilonidal Disease of Natal Cleft
Topical Anti-Androgens in Pilonidal Sinus Disease
The goal of this randomized clinical trial is to test the topical drug clascoterone in patients with pilonidal disease, which is a common, benign skin condition of the gluteal cleft.
- Conditions
- Pilonidal Disease, Pilonidal Disease of Natal Cleft, Pilonidal Sinus, Pilonidal Cyst
- Trial name
- NCT06286397
- Testing
- 1% Clascoterone, Vehicle Cream
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Pennsylvania
Sacral Erector Spinae Plane Block, Pilonidal Sinus
Sacral Erector Spinae Plane Block in Pilonidal Sinus Surgery
This study aims to evaluate the efficacy of ultrasound-guided Sacral Erector Spinae Plane (ESP) block for postoperative analgesia management in patients undergoing pilonidal sinus surgery under general anesthesia
- Trial name
- NCT07534488
- Testing
- Sacral Erector Spinae Plane Block, Standard Postoperative Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Pilonidal Sinus, Pilonidal Disease
Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone)
The goal of this randomized clinical trial is to establish the efficacy of 'pit picking with laser therapy' versus 'pit picking alone' on both short and long-term outcomes in patients of 12 years and older with primary pilonidal…
- Conditions
- Pilonidal Sinus, Pilonidal Disease, Pilonidal Sinus of Natal Cleft, Pilonidal Disease of Natal Cleft
- Trial name
- LA POPA (NCT06140199)
- Testing
- Pit-picking surgery, Pit-picking surgery with Sinus Laser assisted Closure
- Volunteers
- 482 people
- Sponsor
- dr. IJM Han-Geurts
Perianal Crohn Disease, Perianal Fistula
The Impact of Perianal Disease on Patient's Sex Life
Perianal diseases, such as perianal abcesses, anal fistulae and perianal Crohn's disease, are often associated with significant physical symptoms, including pain and chronic drainage.
- Conditions
- Perianal Crohn Disease, Perianal Fistula, Fistula in Ano, Perianal Abscess
- Trial name
- SEXTON (NCT07519850)
- Testing
- Patient Reported Outcome Assessment (Questionnaires)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- AHEPA University Hospital
Pilonidal Sinus
Bascom Cleft Lift for Primary Wound Healing in Complex and Recurrent Sacrococcygeal Pilonidal Sinus Disease
The goal of this observational study is to improve care for patients with complex or recurrent pilonidal sinus disease by developing and implementing a best practice care pathway, including a standardized cleft lift operation.
- Trial name
- BATCRAC (NCT06683274)
- Where
- Netherlands
- Volunteers
- 58 people
- Sponsor
- Albert Schweitzer Ziekenhuis, Netherlands
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection
Myriad™ Augmented Soft Tissue Reconstruction Registry
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures.
- Conditions
- Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus
- Trial name
- MASTRR (NCT05243966)
- Testing
- Myriad Matrix™ and Myriad Morcells™
- Where
- 15 sites in United States
- Volunteers
- 800 people
- Sponsor
- Aroa Biosurgery Limited
Pilonidal Sinus Disorder
Factors Affecting Wound Dehiscence in Pilonidal Sinus Surgery (ORIPIS)
The goal of this multicenter, prospective, observational study is to investigate factors associated with wound dehiscence following pilonidal sinus surgery.
- Trial name
- NCT07370714
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Ankara Etlik City Hospital
Pilonidal Sinus
Prospective Study in Laser Treatment of Pilonidal Cysts
The goal of this observational study is to evaluate the recurrence rate after laser treatment of pilonidal sinus within two years of the procedure in adult patients who require this procedure to treat their pilonidal sinus.
- Trial name
- LASPRO (NCT07314632)
- Where
- 2 sites in France
- Volunteers
- 240 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Pilonidal Sinus Disease
Silac Versus Phenol for the Treatment of Pilonidal Sinus Disease: A Randomized Controlled Trial
Pilonidal sinus disease is a common condition affecting young adults and is associated with pain, infection, and reduced quality of life.
- Trial name
- SILPHEN26 (NCT07420452)
- Testing
- SiLac (Laser Ablation), Phenol Application
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Izmir City Hospital
Non-abscessed Pilonidal Cyst
Cost-utility Analysis of the Use of a Laser Fiber in the Management of Non-abscessed Pilonidal Cyst
This multicenter, prospective, randomized, open-label trial compares laser fiber treatment with conventional surgery in adults with non-abscessed pilonidal cyst.
- Trial name
- ACONIDAL (NCT07652099)
- Testing
- Laser fiber treatment, Conventional surgery
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Elsan
Pilonidal Cyst/Fistula
Evaluation of the Healing of the Pilonidal Cyst After 1940 nm Laser Treatment
The aim of this study is to evaluate the extent to which the reduction of energy absorption that laser 1940 nm allows could improve the outcomes and postoperative results of the treatment of pilonidal cysts.
- Trial name
- PILOLAS 1940 (NCT07269548)
- Testing
- pilonidal cyst laser surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pilonidal Disease
A Trial in Mini-invasive Pilonidal Sinus Disease Surgery
Pilonidal sinus disease is a chronic acquired disease leading to significant morbidity and healthcare costs in young man and women.
- Trial name
- NCT06964763
- Testing
- surgery + laser, surgery + fibrine glue
- Where
- Finland
- Volunteers
- 188 people
- Sponsor
- Helsinki University Central Hospital
Pilonidal Sinus Disease, Laser Therapy
Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus
This study compares two treatment approaches for pilonidal sinus disease: laser treatment alone versus laser treatment combined with phenol application.
- Trial name
- PLEPS (NCT07023952)
- Testing
- Laser Treatment, Crystallized Phenol
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital