Clinical trials: Pilot Study, open to volunteers
Skin Lesion
Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features.
- Trial name
- NCT01771718
- Testing
- Multiphoton microscopy-based tomograph.
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Stress, Burnout
Music Therapy and Humanization in ED Healthcare Professionals
Background: Healthcare professionals in emergency departments frequently experience stressful situations that could jeopardize their mental health, sense of purpose, and ability to empathize with patients, families, and…
- Conditions
- Stress, Burnout, Quality of Life (QOL), Music Therapy
- Trial name
- NCT06939426
- Testing
- Music therapy intervention
- Where
- Colombia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Occupational Diseases, Overweight and Obesity
Nutrition Apps in Occupational Healthcare (Pilot Study of the FOODNUTRI Project)
The aim of this study is to investigate (1) the user experiences and usability of the nutrition apps (the Finnish Nutrition Navigator and the Finnish Nutrition Path) in occupational health care from the perspective of both…
- Conditions
- Occupational Diseases, Overweight and Obesity, Dyslipidemias, Hypertension
- Trial name
- NCT06923735
- Testing
- Utilization of the Finnish Nutrition Navigator and the Finnish Nutrition Path
- Where
- Finland
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Healthy Volunteer, Fatigue
Randomized, Open-label, Safety Study of Subcutaneous and Intramuscular Injections of Niagen® Plus
The goal of this study is to learn about the safety of Niagen®Plus, an injectable form of nicotinamide riboside (NR), and to see how it affects levels of NAD+ in the blood.
- Trial name
- NCT07251608
- Testing
- Niagen®Plus
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ChromaDex, Inc.
Evaporative Dry Eye Disease
Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry Eye
A Pilot Comparative study between I-DROP MGD vs two commercially available lubricant eye drops for the management of evaporative dry eye
- Trial name
- NCT06686368
- Testing
- I-DROP MGD, Theloze Duo, Systane Complete PF
- Volunteers
- 60 people
- Sponsor
- I-MED Pharma
Sexually Transmitted Diseases, Syphilis
Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de Janeiro
The goal of this clinical trial is to learn if doxycycline post-exposure prophylaxis (doxy-PEP) can help prevent bacterial sexually transmitted infections (STIs) among sexual and gender minorities in Rio de Janeiro, Brazil…
- Conditions
- Sexually Transmitted Diseases, Syphilis, Gonorrhea, Chlamydia Infections
- Trial name
- NCT07500415
- Testing
- Doxycycline
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
Sarcopenia
Sarcopenia and Nutritional Status in a Rehabilitation Setting
In this pilot observational study the primary outcome is to assess, in a Respiratory Rehabilitation Unit, if there is an association between sarcopenia, assessed by handgrip strenght and BIA, and a delayed decannulation time in…
- Trial name
- NCT04791540
- Testing
- handgrip strenght, Bioelectrical Impedance Analysis (BIA), MUST
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Aging, Dementia
Feasibility of A Smartphone Application Intervention in Community Settings: A Pretest-Posttest Pilot Study
The objective of this project is to test the feasibility of using a smartphone app in a community setting through collaborating with community-based organizations.
- Conditions
- Aging, Dementia, Cognitive Decline
- Trial name
- NCT07313540
- Testing
- utmbHealthyBrain Smartphone App
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
COPD (Chronic Obstructive Pulmonary Disease)
Virtual Pulmonary Rehabilitation Program for COPD Patients; a Pilot Study
The goal of this pilot study is to investigate the feasibility of a virtual rehabilitation program in COPD patients. The main questions it aims to answer are: 1.
- Trial name
- e-PURE (NCT06915740)
- Testing
- Exercise
- Where
- 2 sites in Finland
- Volunteers
- 50 people
- Sponsor
- Turku University Hospital
Traumatic Brain Injury, Traumatic Brain Injury | Patient
A Pilot Study of Home-Based Rhythmic Auditory Stimulation to Evaluate Mobility, Balance, and Patient-Reported Outcomes After Traumatic Brain Injury
The goal of this study is to learn whether a home-based rhythmic auditory stimulation (RAS) program using the MR-001 device can help improve walking, balance, and other health outcomes in adults with moderate to severe traumatic…
- Conditions
- Traumatic Brain Injury, Traumatic Brain Injury | Patient, TBI, TBI-Traumatic Brain Injury
- Trial name
- BEAT TBI (NCT07702513)
- Testing
- Home-Based Rhythmic Auditory Stimulation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Craig Hospital
Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee
Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction
The goal of this pilot randomized clinical trial is to look into the efficacy of concentrated bone marrow aspirate (cBMA) in improving post traumatic osteoarthritis (PTOA) symptoms in patients undergoing revision anterior…
- Conditions
- Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee, Bone Marrow Aspirate Concentrate, ACL Injury
- Trial name
- NCT06311513
- Testing
- Concentrated Bone Marrow Aspirate Injection, Revision Anterior Cruciate Ligament Reconstruction
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Hospital for Special Surgery, New York
Sleep Quality, Menopause
Effect of ZenRest™ Lotus Seed & Rice Germ Extract Blend on Sleep Quality in Menopausal Women
The goal of this clinical trial is to learn if ZenRest™ (Lotus Seed \& Rice Germ Extract Blend) can help improve sleep quality in menopausal women aged 40-65 with mild-to-moderate sleep complaints.
- Trial name
- NCT07678359
- Testing
- Lotus Seed & Rice Germ Extract
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Public Speaking Anxiety
HablaRÉ: Self-applied Online Training for Correcting Emotional Reasoning Biases in Public Speaking Anxiety.
The project aims to assess the feasibility of self-administered training for individuals with public speaking anxiety, specifically targeting the reduction of emotional reasoning bias.
- Trial name
- NCT07051135
- Testing
- "HablaRÉ": Emotional Reasoning bias correction training
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universitat Jaume I
Bone Marrow Edema, Knee Osteoarthritis
Focused Extracorporeal Shockwave Therapy for Knee Arthritis
Subchondral bone marrow lesions (BMLs) in knee osteoarthritis (OA) are strongly associated with presence and severity of knee pain, structural deterioration, disease progression with an increased risk of total knee arthroplasty.
- Conditions
- Bone Marrow Edema, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NCT05596591
- Testing
- Focused extracorporeal shockwave therapy
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Kessler Foundation
Cardiogenic Shock, IABC Procedure
Intra-aortic Balloon Counterpulsation (IABC) Compliance
The investigators intend to study how baseline arterial compliance (as defined by stroke volume/pulse pressure) influences the clinical success of intraaortic balloon counterpulsation (IABC) in patients with cardiogenic shock…
- Conditions
- Cardiogenic Shock, IABC Procedure, Intraaortic Balloon Counterpulsation (IABC)
- Trial name
- NCT07402018
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University
Major Depressive Disorder (MDD), Borderline Personality Disorders
Home-Based tDCS for Depression in BPD
The present study aims to assess the feasibility of home-based tDCS in remote and urban areas (primary objective). The secondary aim is to obtain a preliminary assessment of the efficacy of 14 home-based tDCS sessions in reducing…
- Trial name
- TENTADIS (NCT06972368)
- Testing
- tDCS, Treatment as Usual (TAU), Psychoeducation
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Checkpoint Inhibitor, Pilot Study
Checkpoint Inhibitor Associated Diabetes Mellitus: Early Recognition and Treatment (CERT) Project: A Pilot Study
To find out if taking a drug called infliximab (the "study drug") is safe and effective in reversing insulin dependence in CIADM.
- Conditions
- Checkpoint Inhibitor, Pilot Study, Diabetes Melletus
- Trial name
- NCT07257068
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- M.D. Anderson Cancer Center
POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE, Heart Rate Variability
Predicting Postoperative Delirium With Heart Rate Variability Obtained by Analgesia Nociception Index
The aim of this pilot study is to establish a correlation between perioperative heart rate variability (HRV) as an expression of the shift in the balance of the autonomic nervous system and the occurrence of postoperative…
- Conditions
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE, Heart Rate Variability, Biomarkers
- Trial name
- DANI (NCT06709482)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm
Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal, Gynecological, Breast, or Lung Cancer
This phase II trial tests how well fucoidan works in preventing chemotherapy-related fatigue compared to a placebo in patients with gastrointestinal (GI), gynecological (GYN), breast, or lung cancer.
- Conditions
- Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm, Breast Carcinoma, Lung Carcinoma
- Trial name
- NCT06855524
- Testing
- Biospecimen Collection, Oligo-fucoidan, Questionnaire Administration
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Mayo Clinic
PCOS (Polycystic Ovary Syndrome), Cumulus Cell
Transcriptomic Profiling of Cumulus Cells From CAPA-IVM
Capacitation in vitro maturation (CAPA-IVM) has improved oocyte maturation and resulted in live births. Because cumulus cells (CCs) communicate bidirectionally with the oocyte, their transcriptomic profile may serve as a…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Cumulus Cell, Capacitation IVM, Transcriptomic Profiling
- Trial name
- NCT07197255
- Where
- Vietnam
- Volunteers
- 10 people
- Sponsor
- Mỹ Đức Hospital
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