Clinical trials: Placenta; Implantation
Sterility, Placenta; Implantation
A Lifestyle Intervention to Improve in Vitro Fertilization Results
Embryo adhesion and placentation depend on tissue plasminogen activator (tPA)-mediated activation of brain-derived neurotrophic factor, vascular endothelial growth factor and other growth factors, formation of hemidesmosomes, and…
- Conditions
- Sterility, Placenta; Implantation, Risk Reduction Behavior, Lifestyle
- Trial name
- W+D (NCT02648555)
- Testing
- Daily walking, Dietary recommendations
- Where
- Brazil
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Placental Development Pregnancy Outcome
Peri-implantation Abstinence and Placental Health
This study examined whether avoiding sexual intercourse during the time when a fertilized egg may attach to the uterus affects placental development and pregnancy outcomes.
- Trial name
- NCT07843173
- Testing
- Couples were instructed to avoid sexual intercourse for 14 days after ovulation during each study cycle, covering the expected peri-implantation period.
- Where
- Malaysia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Placenta; Implantation
MRI Screening of Placenta Adhesion Abnormalities
Placenta Adhesion Abnormalities (PAA) are the consequence of an excessive invasion of the placenta within the myometrium. PAA are related to severe maternal pregnancy outcomes, especially in case of incidental discovery during…
- Trial name
- DIANE (NCT04328532)
- Testing
- MRI
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Central Hospital, Nancy, France
Placenta Previa
Relation of Implantation Site to Placental Site in Presence or Absence of Cesarean Section Scar
After gaining verbal consent , Patients included in this study will be subjected to: 1. history taking : peronal history . obstetric history. past history 2. general examination including vital signs 3.
- Trial name
- NCT03208842
- Testing
- trans vaginal ultrasound
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Placenta; Implantation
The Effect of Laser Assisted Hatching in Thawing Cycles: a Prospective Randomized Controlled Study
The successful hatching process is a prerequisite for implantation. Freezing/thawing cycles can impair the hatching process by introducing changes in the composition of the zona pellucida.
- Trial name
- NCT00593775
- Testing
- assisted hatching
- Where
- Belgium
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Placenta; Implantation
Prospective Randomized Study to Evaluate the Effect of Embryonic Observation on the Gestation (PROdE)
In a conventional in vitro fertilization (IVF) cycle, daily microscopic observation of embryos outside the incubator to assess their morphology and establish a selection process is performed.
- Trial name
- PROdE (NCT02372279)
- Testing
- Embryo observation
- Where
- Spain
- Volunteers
- 193 people
- Sponsor
- Instituto Bernabeu
Infertility
Site of Embryo Transfer in Intracytoplasmic Sperm Injection
The technique of embryo transfer is thought to affect the implantation and pregnancy rate .At present, the implantation site can be estimated from the location of the very early gestational sac by transvaginal ultrasound.
- Trial name
- NCT05004922
- Testing
- Embryo transfer into upper cavity, Embryo transfer into midcavity
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Infertility, Female, Infertility of Uterine Origin
Progesterone Levels and Endometrial Compaction in Frozen-Thawed Embryo Transfer Cycles
This study is intended to determine whether there is a correlation between endometrial compaction and serum progesterone levels on the day of frozen embryo transfers by using transvaginal sonography for the endometrial assessment.
- Conditions
- Infertility, Female, Infertility of Uterine Origin, Implantation; Placenta
- Trial name
- NCT04554654
- Testing
- transvaginal ultrasound,
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cem Demirel
Implantation; Placenta, Pregnancy Loss
Luteal Support in Frozen-Thawed Embryo Transfer Cycles
This study evaluates the clinical efficacy of 3 different luteal phase support in patients undergoing frozen-thawed embryo transfer cycles. Endometrium preparation will be hormone replacement in all cycles.
- Conditions
- Implantation; Placenta, Pregnancy Loss, Frozen Embryo, Luteal Support
- Trial name
- NCT03948022
- Testing
- Dydrogesterone 10Mg Tablet (duphaston), Progesterone 50Mg/mL Oil, Crinone 8% Vaginal Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
Complications Associated With Artificial Fertilization, Placenta; Implantation
Effect of Assisted Hatching on Vitrified Embryo Transfer Clinical Outcome
The objective of study is to assess the possible impact of assisted hatching on the implantation, pregnancy rate and delivery rate after transfer of vitrified-warmed human embryos.
- Conditions
- Complications Associated With Artificial Fertilization, Placenta; Implantation, Pregnancy
- Trial name
- VitHatSZMC (NCT02124291)
- Testing
- Mechanical Assisted Hatching
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Shaare Zedek Medical Center
Placenta Implantation Site
Relation of Implantation Site to Placental Site
Trans vaginal ultrasound with a partially full bladder will be done at gestational age earlier than 10 weeks to assess the site of intrauterine gestational sac to the endometrial cavity and the distance between the implantation…
- Trial name
- NCT02765984
- Testing
- Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Pregnancy, Preeclampsia
The Involvement of Eukaryotic Translation Initiation Factor 4E (eIF4E) in Human Placental Implantation and in the Pathological Pregnancies: Preeclampsia and IUGR
The involvement of eukaryotic translation initiation factor 4E (eIF4E) in human placental implantation and in the pathological pregnancies: preeclampsia and IUGR.
- Trial name
- NCT01179542
- Volunteers
- healthy volunteers welcome
- Sponsor
- Meir Medical Center
Placenta; Implantation
The Accuracy of Ultrasound in the Detection of Placenta Site in the First Trimester.
The investigators speculate that ultrasound examination in the first trimester can accurately detect placental location. By performing both transabdominal ultrasound and later hysteroscopy on women with a first trimester missed…
- Trial name
- NCT04579796
- Testing
- ultrasound exam, hysteroscopy diagnostic
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center