Clinical trials: Placenta
To Publish Our Experience in the Surgical Management to Placenta Accreta Cases and the Maternal Outcome
Surgical Management of Placenta Accreta
purpose of this study was to report our experience for surgical management of suspected placenta accreta cases encountered in King Hussein medical center
- Trial name
- NCT03668795
- Testing
- Bakrey balloon insertion within the uterus and caesarean hysterectomy
- Volunteers
- 40 people
- Sponsor
- Royal Medical Services, Jordanian Armed Forces
Placenta Previa
Effect of Uterine Artery Ligation Prior to Uterine Incision in Women With Placenta Previa
Pfannenstiel incision of skin and opening of the anterior abdominal wall in layers. The loose peritoneum of the lower uterine segment is dissected downwards to mobilize the urinary bladder and expose the lower uterine segment.
- Trial name
- NCT03124472
- Testing
- uterine artery ligation, Lower segment Cesarean section
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Pregnancy Complications
Prenatal Sonographic Prediction of Placental Histology and Function
The purpose of this two-phase observational study is to investigate the use of ultrasonography to predict placental pathology at the time of delivery.
- Trial name
- NCT06022458
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Covid19, Obstetric Complication
COVID-19 Infection and Fetal-neonatal Outcomes
COVID-19, the coronavirus responsible for the pandemic that began at the end of 2019 in China, spreads through respiratory droplets and direct contact.
- Conditions
- Covid19, Obstetric Complication, SARS-CoV Infection, Preterm Birth
- Trial name
- NCT04699578
- Testing
- Covid-19 positive
- Where
- Italy
- Volunteers
- 230 people
- Sponsor
- University of Campania Luigi Vanvitelli
Blood Loss, Surgical
B-lynch Transverse Compression Suture
Is B-Lynch transverse compression suture safe and effective in controlling excessive blood loss during conservative management of women with placenta previa?
- Trial name
- NCT06359886
- Testing
- B-Lynch Transverse Compression Suture
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Alexandria University
Placenta; Implantation
Prospective Randomized Study to Evaluate the Effect of Embryonic Observation on the Gestation (PROdE)
In a conventional in vitro fertilization (IVF) cycle, daily microscopic observation of embryos outside the incubator to assess their morphology and establish a selection process is performed.
- Trial name
- PROdE (NCT02372279)
- Testing
- Embryo observation
- Where
- Spain
- Volunteers
- 193 people
- Sponsor
- Instituto Bernabeu
Abruptio Placentae
Plasma Concentration of Biological Markers in Placental Abruption
This will be a prospective study conducted on women with a suspected/confirmed diagnosis of placental abruption. Maternal blood samples will be taken at various points during the peripartum period.
- Trial name
- NCT03782168
- Testing
- There is no other intervention, only clinical treatment.
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Arkansas
Normal Pregnancy
Using Cotyledon Perfusion to Study Drugs Transfer Across the Placenta
Drug prescriptions are usual during pregnancy however women and their fetuses still remain an orphan population with regard to drugs efficacy and safety clinical studies.
- Trial name
- DRUGS-PTP (NCT04400084)
- Testing
- Placenta perfusion
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vitamin A Deficiency
Retinol Status in Preterm Infants and Mothers
Retinol and retinol binding protein were studied in the umbilical cord blood of 44 preterm infants with gestation age of < 30 weeks. Serum retinol and RBP levels were determined by enzyme-linked immunosorbent assay.
- Trial name
- NCT04780958
- Testing
- Serum retinol and RBP levels were determined by enzyme-linked immunosorbent assay.
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Homozygous αº-thalassemia, Hb Bart's Disease
Use of 3D/4D Ultrasound in the Evaluation of Fetal Anomalies
Volumetry measurements can be a potential clinical use as non-invasive tools in prenatal diagnosis and screening and helps to reduce the risk and complications of invasive procedures.
- Trial name
- NCT00826917
- Where
- China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pregnant Women Receive Celesten
Betamethasone and Severity of Hyaline Membrane Disease
Primary purpose: to study the relationship between betamethasone placental transfer and the occurrence and severity of the Hyaline Membrane Disease.
- Trial name
- b-Mhyalines (NCT01854840)
- Where
- France
- Volunteers
- 127 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Eye Diseases, Retinitis Pigmentosa
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAION
This trial will study the safety and efficacy of intranasal delivery of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exosomes for the treatment of non-arteritic ischemic optic neuropathy
- Conditions
- Eye Diseases, Retinitis Pigmentosa, Diabetic Retinopathy, Macular Degeneration
- Trial name
- NCT05147701
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exosomes
- Where
- 2 sites in United States, Greece
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Dental Extraction
Human Placenta Extract Use in Socket Preservation
This split-mouth pilot study evaluates the effectiveness of flowable decellularized Human Placental Connective Tissue Matrix (HPCTM) in alveolar ridge preservation following tooth extraction.
- Trial name
- NCT06915675
- Testing
- Placental Extract, Allograft
- Where
- Lebanon
- Volunteers
- 10 people
- Sponsor
- Saint-Joseph University
Placenta Accreta Spectrum
MOGGE PAR Scores for Prediction of Outcomes of PAS
Placenta accreta spectrum (PAS) is a set of placentation disorders that are associated with trophoblastic invasion through the physiologic decidual-myometrial junction zone.
- Trial name
- PAR (NCT04525001)
- Volunteers
- 200 people
- Sponsor
- Assiut University
Preeclampsia
Low Dose Aspirin for the Prevention of Preeclampsia
Preeclampsia is one of the three leading causes of maternal morbidity and mortality all over the world. The use of low dose aspirin has been mentioned in several studies with promising results.
- Trial name
- NCT01890005
- Testing
- Aspirin
- Where
- Panama
- Volunteers
- 476 people
- Sponsor
- Saint Thomas Hospital, Panama
Cervical IO Plasty in Management of Placenta Previa
Cervical Internal os Plasty in Management of Placenta Previa and Focal Accreta
Aim of the work: Better management \& reducing hemorrhage and complication in patients placenta previa and focal accreta .
- Trial name
- NCT05560984
- Testing
- cervical internal os plasty
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Premature Birth of Newborn, Infant, Very Low Birth Weight
Delayed Cord Clamping in Preterm Neonates
Delayed cord clamping (DCC) from 30 to 60 seconds allows blood to continue to flow from the placenta through the umbilical cord to the infant, thus resulting in a placental transfusion.
- Conditions
- Premature Birth of Newborn, Infant, Very Low Birth Weight, Delayed Separation of Umbilical Cord, Placental Transfusion
- Trial name
- DCC (NCT02478684)
- Testing
- 30 Seconds of placental blood transfusion, 60 Seconds of placental blood transfusion
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Weill Medical College of Cornell University
Pregnancy, Pregnancy in Diabetes
Exploration of the Lipid Metabolism During the Diabetic Pregnancies
Justification: Intrauterine exposure to type 1 or type 2 diabetes increase the risk of macrosomia (35 % to 50 % versus 10 % in general population) despite a good glycemic control.
- Conditions
- Pregnancy, Pregnancy in Diabetes, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
- Trial name
- DIAMANT (NCT00639964)
- Testing
- blood tests, diet questionnaire, umbilical cord blood collect
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Morbidly Adherent Placenta
Morbidly Adherent Placenta, Diagnosis and Proper Management
The main idea of this study is to establish the diagnostic criteria for cases of morbidly adherent placenta (MAP) using different ultrasonographic modalities and compare this with intra-operative findings and postoperative…
- Trial name
- NCT05307016
- Testing
- Two dimensional ultrasonography power and color doppler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University