Clinical trials: Placenta
Fever
Evaluation of Fever Occurring in Labor in Patients Receiving Epidural Anesthesia
Briefly, the investigators propose to evaluate nulliparous (first time mothers) patients beyond 36 0/7 weeks' gestation in active labor who already have received epidural anesthesia and have an intrauterine pressure catheter…
- Trial name
- NCT00326521
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Placenta Previa
Low Implanted Second Trimester Placenta and Placenta Previa
Placenta Previa is defined as a placenta implanted in the lower segment of the uterus, presenting ahead of the leading pole of the fetus (over or near the internal os).
- Trial name
- NCT03431116
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intermittent Preventive Treatment, Placental Malaria
Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda
The effectiveness of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy in malaria-endemic areas the effectiveness and efficacy of SP may be compromised by increased SP resistance.
- Trial name
- SP IPTp (NCT01184911)
- Testing
- Sulfadoxine-pyrimethamine
- Where
- Uganda
- Sponsor
- University of California, San Francisco
Placenta Previa
Cervical Length in Cases of Placenta Previa
This study establishes the relationship between cervical length and whether it can be used to predict haemorrhage and preterm delivery in cases of placenta previa.
- Trial name
- NCT03451136
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Preterm Infant, Placental Insufficiency
Effect of Delayed Cord Clamping in Preterm Neonates With Placental Insufficiency
To investigate the effect of delayed cord clamping (DCC) on hematopoietic progenitor cells (HPCs), hematological parameters including haemoglobin concentration and hematocrit value in premature infants (34 weeks gestational age…
- Conditions
- Preterm Infant, Placental Insufficiency, Placental Transfusion
- Trial name
- NCT03731546
- Testing
- Delayed cord clamping
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University Children Hospital
Preeclampsia, Intrauterine Growth Restriction
First Trimester Placental Assessment in the Screening of Preeclampsia and Intrauterine Growth Restriction
Preeclampsia (PE) and intrauterine growth restriction (IUGR) are clinical manifestations of placental insufficiency. These complications affect 5-15% of pregnancies, and are responsible for up to 20% of preterm births.
- Trial name
- NCT02879942
- Testing
- Ultrasound study of the placenta, Measurement of angiogenic and anti-angiogenic factors (sFlt-1 and PlGF) in the first trimestre blood test
- Where
- Spain
- Volunteers
- 1,390 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Pregnancy Related, Trauma
The Use of Fetal Fibronectin to Predict Delivery Due to Abruptio Placenta
The purpose of this study is to determine if the presence of fetal fibronectin in the cervicovaginal secretions of pregnant patients with minor maternal trauma predicts impending preterm delivery due to abruptio placenta.
- Conditions
- Pregnancy Related, Trauma, Abruptio Placentae
- Trial name
- NCT01279369
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Winthrop University Hospital
Placenta Accreta
Early Prediction of Placenta Accreta by Ultrasound and Color Doppler
Placenta accreta is a substantially life threatening condition and one of the causes of maternal morbidity and mortality in the world.
- Trial name
- NCT03032770
- Testing
- two-dimensional ultrasound and color Doppler
- Where
- Egypt
- Volunteers
- 148 people
- Sponsor
- Assiut University
Placenta Previa
Vaginal Progesterone Versus 17-Alpha-Hydroxyprogesterone Caproate in Placenta Previa
Purpose to evaluate the effects of Vaginal Progesterone versus 17-Alpha-Hydroxyprogesterone Caproate for prevention of Emergent Cesarean Delivery in Asymptomatic Pregnant Women with Placenta Previa
- Trial name
- NCT03779451
- Testing
- 17-OHPC, vaginal progesterone
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Aswan University Hospital
Morbidly Adherent Placenta
Role of Ultrasound in Diagnosis of Placenta Previa and MAP
Placenta accreta occurs when the placental implantation is abnormal. The marked rise in incidence has been assumed the increasing prevalence of cesarean delivery in recent years.
- Trial name
- NCT03416296
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Preeclampsia
PP13 and Doppler Study to Predict Preeclampsia
Assessment of biochemical and sonographic marker to predict the risk for developing preeclampsia Among biochemical markers are serum level of Placental Protein 13 (PP13) and Placenta Growth factor (PIGF).
- Trial name
- NCT00928213
- Testing
- Progesterone, Low molecular weight Heparin, No Drug
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Ben-Gurion University of the Negev
Placenta Accreta Spectrum
Blood Components Changes by Using of Ringer's Lactated as Detergent In Autologous Blood Cell Transfusion
Placenta accreta spectrum (PAS) disorders are associated with increased maternal morbidity and mortality related to life-threatening hemorrhage, and greater potential need for blood transfusion.
- Trial name
- NCT04927988
- Testing
- Ringer's Lactated
- Where
- China
- Sponsor
- Maternal and Child Health Hospital of Foshan
Pregnancy Related
Fetal MRI Acquisition and Sequence Development
Testing of new magnetic resonance imaging (MRI) pulse sequences (image acquisition software) for imaging the fetus to improve workflow and image quality in fetal imaging and diagnosis.
- Trial name
- FMASD (NCT05253742)
- Testing
- No intervention - the investigators are evaluating a new image acquisition method on an MRI scanner
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pregnancy Related
Longitudinal Study of Gene Expression in the Human Placenta During First-trimester and Full-term Pregnancy at the Single Cell Level
The single nucleus RNA-seq approach allows the placental transcriptome to be analyzed from nuclei, thus preserving the integrity of placental syncytium.
- Trial name
- VilliRNAseq (NCT06427408)
- Testing
- Non applicable
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dysbiosis, Inflammation Gum
Microbiome Alterations With Xylitol (MAX) in Pregnancy
The purpose of this study is to understand if chewing xylitol-gum initiated before 20 weeks of pregnancy and continued until delivery affects the bacteria that are found in the oral and vaginal cavities, signs of inflammation…
- Conditions
- Dysbiosis, Inflammation Gum, Placenta-mediated Pregnancy Complications, Microbioata
- Trial name
- MAX (NCT06329596)
- Testing
- Xylitol gum, Sorbitol gum
- Where
- Malawi
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Lung; Premature, Pollution; Exposure
Ultrafine Particles and Fetal Contamination
The objective of this study is to evaluate the transplacental passage of fine and ultrafine particles (nanoparticles) inhaled by the mother.
- Trial name
- FOETOPUF (NCT04068389)
- Testing
- Pulmonary Tissue Collection
- Volunteers
- 62 people
- Sponsor
- University Hospital, Bordeaux
Peripheral Arterial Disease, Diabetic Foot Ulcer
Study of PDA-002 in Subjects With Peripheral Arterial Disease and Diabetic Foot Ulcers
This Phase 1, multicenter, open-label, dose-escalation study evaluated the safety and tolerability of intramuscular administration of PDA-002 (human placenta-derived cells) in subjects with peripheral arterial disease (PAD) and…
- Trial name
- NCT01859117
- Testing
- PDA-002
- Where
- 12 sites in United States
- Volunteers
- 15 people
- Sponsor
- Celularity Incorporated
Placental Volume
Placental Thickness And Volume Nomogram In Normal Singleton Pregnancies Between 11th And 18th Week Gestational Age
Measurement of placental thickness and volume has a great importance in predicting adverse outcome specially in combination with other markers.
- Trial name
- NCT06561490
- Testing
- sonographic assesment of placental thickness and volume
- Volunteers
- 100 people
- Sponsor
- Sohag University
Jaundice Neonatal
The Risk of Hyperbilirubinemia in Term Newborns After Placental Transfusion
Delayed cord clamping (DCC) has been a subject of extensive research for the last couple of years. Based on published data, numerous neonatal benefits have been suggested such as increased hemoglobin and ferritin levels both at…
- Trial name
- NCT02625688
- Testing
- Delayed cord clamping, Cord milking, Early cord clamping
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Delay Cord Clamping, Placental Trasfusion
Position at Birth,Placental Transfusion Volume and Cord Clamping
To compare the evolution of the infant's weight before delayed cord clamping (2 minutes after birth) as an indirect measure of the volume of placental transfusion in a group of healthy and fullterm newborns, placed at the level…
- Trial name
- NCT01497340
- Testing
- Position at introitus level, Position at Maternal Abdomen
- Where
- Argentina
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Salud Materno Infantil