Clinical trials: Placenta
Intraventricular Hemorrhage, Sepsis
Placental Transfusion Project for Preterm Infants
The American College of Obstetrics and Gynecology, American Academy of Pediatrics and the World Health Organization have recently published recommendations related to placental transfusions in preterm infants.
- Conditions
- Intraventricular Hemorrhage, Sepsis, Necrotizing Enterocolitis
- Trial name
- NCT02400697
- Testing
- <30 wks gestation or 1500 grams
- Where
- United States
- Volunteers
- 2,856 people
- Sponsor
- Indiana University
Placenta Accreta
The Role of Transdermal CO2 in MDA Level in Patient Underwent Abdominal Aortic Temporary Cross Clamp
The Role of Transdermal Carbon Dioxide in Malondialdehyde Level as Predictor of Ischemia Reperfusion Injury in Patients Underwent Abdominal Aortic Temporary Cross Clamp
- Trial name
- NCT05205304
- Testing
- D'Oxyva
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Airlangga
Peripheral Artery Disease, Peripheral Vascular Disease
Safety of Intramuscular Injection of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia
The The purpose of this study is to determine the safety of PLX-PAD single dose, Intra-muscular injection for the treatment of CLI patients.
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Critical Limb Ischemia
- Trial name
- NCT00919958
- Testing
- PLX-PAD IM injection
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Pluristem Ltd.
Inflammatory Bowel Diseases
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for Crohn's Disease or Ulcerative Colitis
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Crohn's Disease or Ulcerative Colitis
- Trial name
- NCT05003947
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 15 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Diabetic Foot Ulcer, Amniotic Membrane Placental Allograft
a Prospective, Multicenter, Randomized Controlled Trial, With a Non-randomized Sentinel Cohort, Evaluating the Efficacy of Bioxheal, a Single-layer Placental-derived Biologic in Nonhealing Diabetic Foot Ulcers
BIOxHEAL is an investigational placental-derived biologic being evaluated for the treatment of nonhealing diabetic foot ulcers. Adults with type 1 or type 2 diabetes who have a diabetic foot ulcer that has not healed with…
- Conditions
- Diabetic Foot Ulcer, Amniotic Membrane Placental Allograft, Biologic
- Trial name
- AB BIOH - DFU (NCT07852338)
- Testing
- Standard of Care, BIOxHEAL (human amniotic membrane allograft)
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- Applied Biologics, LLC
Placenta Previa
Effect of a Cervical Pessary on the Rate of Bleeding in Placenta Praevia
This study evaluates whether use of a cervical pessary can reduce vaginal bleeding and prolong pregnancy in women with placenta previa or a low-lying placenta.
- Trial name
- NCT07667777
- Testing
- Cervical pessary
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- Asklepios proresearch
Cerebral Palsy
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CP
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Cerebral Palsy
- Trial name
- NCT05018819
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 15 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Climacteric Syndrome
Efficiency of Placental Drug Melsmon® in Correction of Climacteric Symptoms in Premenopausal Women
The placental drug Melsmon® is effective for correction of insomnia and other climacteric symptoms in premenopausal women. Decrease of MMI is shown both in groups with Melsmon® and Placebo, but it was more significant in patients…
- Trial name
- NCT02749695
- Testing
- Melsmon
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Inna I. Kovalenko
PPROM, Preterm
Preterm Rupture of Membranes Optimising Antibiotics Trial
The goal of this clinical trial is to learn which antibiotic regimen works best to prevent infection in pregnant women whose waters break early (preterm, pre-labour rupture of membranes, or PPROM) and assess the health outcomes…
- Trial name
- PROMOAT (NCT06906757)
- Testing
- Erythromycin 250mg and Amoxicillin 500mg
- Volunteers
- 3,900 people
- Sponsor
- University of Melbourne
Complete Placenta Previa
Efficacy Study of Random Placenta Margin Incision to Treat Complete Placenta Previa
The purpose of this study is to assess the efficacy of random placenta margin incision for hemorrhage control during cesarean section of complete placenta previa pregnancies.
- Trial name
- NCT02695069
- Testing
- Random Placenta Margin Incision
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Cancer
The Effect of Human Placental Explants and Pregnant Women Sera on Cancer Cells
Maternal malignancy during pregnancy is estimated to occur in 1 out of 1000 pregnancies. Controversy exists regarding the effect of pregnancy on cancer prognosis.
- Trial name
- NCT01879436
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pregnancy
The Effect of 7 Days of Letrozole Pretreatment Combined With Misoprostol on the Placental and Decidual Tissues
The present study aims at studying the effect of letrozole in early pregnancy in placenta and decidua including the progesterone receptor and the apoptotic factors.
- Trial name
- NCT02457312
- Testing
- Letrozole
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Placenta Accreta, Cesarean Hysterectomy
Conservative Treatment of PAS With or Without IIL
In the current study, the investigators aimed to compare the benefits of internal iliac ligation in placenta accreta spectrum
- Conditions
- Placenta Accreta, Cesarean Hysterectomy, Pelvic Devascularization
- Trial name
- PASIIL (NCT05232981)
- Testing
- Ligation of the bilateral internal iliac arteries, Shehat's technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Placenta Accreta
Descriptive Study of the Incidence and Outcome of PAS in Two Large Referral Hospitals in Egypt
placenta accreta spectrum incidence and outcome
- Trial name
- NCT05636865
- Where
- Egypt
- Volunteers
- 10,000 people
- Sponsor
- Cairo University
Premature Birth, Placenta Previa
Cerclage for Prevention on Preterm Birth in Women With Placenta Previa
The purpose of the study is to compare the role of cervical cerclage versus expectant management in women with complete placenta previa (≥ 10mm over internal os) presenting with shortened cervical length ( ≥ 10mm and ≤ 30mm)…
- Trial name
- NCT01442207
- Testing
- Placement of a Cervical Cerclage, Standard Expectant Management
- Volunteers
- healthy volunteers welcome
- Sponsor
- Obstetrix Medical Group
Diabetic Foot
Efficacy of Human Placental Graft in Diabetic Foot Ulcers
To determine the efficacy of full-thickness placental allograft in chronic wound healing
- Trial name
- NCT03708029
- Testing
- Revita Allograft
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- StimLabs
Prevenetion of Intrauterine Adhesions by Hyaluronic Acid Gel
Intrauterine Hyaluronic Acid Gel for Prevention of Intrauterine Adhesions
Women undergoing operative hysteroscopy for removal of retained placenta after delivery will be randomized into two groups. 1. study group - immediately after operative hysteroscopy 5 ml hyaluronic acid gel will be injected into…
- Trial name
- NCT04975373
- Testing
- Intrauterine injection of hyaluronic acid
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Barzilai Medical Center
Placenta Previa
Characteristics, Complications and Perinatal Outcomes in Placenta Previa Women
This study aim to investigate the characteristics, complications and perinatal outcomes in pregnant women with placenta previa.
- Trial name
- NCT03774667
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Maternal and Child Health Hospital of Foshan
Fetal Membranes, Premature Rupture
Safety and Efficacy Study of Intentional Delivery in Women With Preterm and Prelabour Rupture of the Membranes
Two-year multicentre randomized controlled parallel trial to compare intentional delivery and conservative management in pregnant women with preterm and prelabour rupture of membranes between 32 and 35 weeks.
- Trial name
- NCT00259519
- Testing
- Induction of delivery
- Where
- 11 sites in Canada
- Volunteers
- 152 people
- Sponsor
- University of Alberta
Gestational Diabetes Mellitus
Study of Pregnancy Regulation of Insulin and Glucose
It is unknown whether beta cell dysfunction and insulin resistance in Gestational Diabetes Mellitus (GDM) is representative of a chronic maternal defect, unmasked by pregnancy, or whether it is the result of an imbalance of a…
- Trial name
- SPRING (NCT02763267)
- Testing
- Oral glucose tolerance test
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Massachusetts General Hospital