Clinical trials: Placenta Accreta Spectrum
Placenta Accreta, Third Trimester
A Serum Galectin-3 Levels in Placenta Accreta Spectrum Pregnancies
Placenta Accreta Spectrum (PAS) represents a significant cause of maternal morbidity and mortality, causing complications that surpass those posed by most routine obstetric issues.
- Trial name
- NCT05945446
- Testing
- Galectin 3
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Placenta Previa, Placenta Accreta
Outcomes of Placenta Accreta Spectrum Disorders Surgery in Relation to Placenta Accreta Scoring Index
Using of Ultra sound in assessment of Placenta Accreta Index to predict the surgical outcomes of Placenta accreta
- Trial name
- NCT06220760
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Assiut University
Placenta Previa, Placenta Accreta Spectrum
Syncytiotrophoblast-derived Extracellular Vesicles in Placenta Previa and Accreta Spectrum
The main goal of this case-control study is to quantify the levels of circulating syncytiotrophoblast-derived extracellular vesicles (STBEVs) in maternal blood in a population of women with placenta previa and placenta accreta…
- Trial name
- PAS (NCT06867874)
- Testing
- Blood sample
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Placenta Accreta, Third Trimester
Relationship Between Maternal Soluble Trigger Receptor Expressed on Myeloid Cells-1 (sTREM-1) and Placenta Accreta Spectrum
We planed to evaluate soluble the triggering receptors expressed on myeloid cell-1 (s TREM-1) levels in serum of pregnant women diagnosed with placenta accreta spectrum and compare it with healthy pregnant women's s TREM-1 serum…
- Trial name
- NCT05376410
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Placenta Accreta, Unspecified Trimester
Association of Ultrasonographic Parameters With FIGO Clinical Grading System for Placenta Accreta Spectrum
To evaluate the association of ultrasonographic parameters suggestive of placenta accreta with intraoperative clinical diagnosis of placenta accreta according to the the clinical grading system for placenta accreta spectrum (PAS)…
- Trial name
- NCT04801706
- Testing
- Ultrasound
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Assiut University
Placenta Accreta, Placenta Diseases
Plasma Concentration of Biological Markers in Placenta Accreta Spectrum
The purpose of this exploratory study is to determine how well maternal serum biomarkers and placental micro-particles (MP) correlate with placenta accreta spectrum (PAS) at the time of cesarean delivery in women with suspected…
- Trial name
- NCT04525534
- Testing
- There is no other intervention, only clinical treatment.
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Placenta Accreta
A Comparison Between Bladder Dissection Before and After Uterine Incision During Cesarean Section for Placenta Accreta Spectrum: A Randomized Controlled Study
The worldwide incidence of placenta accreta spectrum is increasing, following the trend of rising caesarean delivery. It is an heterogeneous condition associated with a high maternal morbidity and mortality rate (Jauniaux et al.…
- Trial name
- NCT06957184
- Testing
- bladder dissection in placenta accreta spectrum
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Placenta Accreta, Third Trimester
Placenta Accreta Index Score in Placenta Accreta Spectrum
role of placenta accreta index score in prediction of conservative surgery for placenta placenta accreta spectrum
- Trial name
- NCT05513092
- Testing
- placenta accreta index score
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Placenta Accreta
3D Placental Volume in Placenta Accreta
Placenta Accreta spectrum is a major obstetric disease nowadays. Different methods are used for antenatal diagnosis. In our study, investigators are aiming to compare 2 common ways for diagnosis, i.e; 3D Ultrasound and 2D with…
- Trial name
- NCT06755047
- Testing
- 3D Ultrasound, 2D ultrasound
- Where
- Egypt
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Assiut University
Blood Loss, Repeat Cesarean Section
Cesarean Scar Pregnancy and Clinical Outcomes
This study is a prospective cohort study, led by Prof. Zhao Yangyu, from the Department of Gynecology \& Obstetrics, Peking University Third Hospital.
- Conditions
- Blood Loss, Repeat Cesarean Section, Maternal Transmission, Hysterectomy
- Trial name
- NCT05481606
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Placenta Accreta, Placenta Previa
Topical Adrenaline Versus Warm Saline Solution for Minimizing Intraperitoneal Bleeding During Caesarian Delivery for Placenta Previa / Accreta Spectrum ( PAS)
Placenta accreta spectrum (PAS), encompassing the terms placenta accreta, increta, and percreta; abnormally invasive placenta; morbidly adherent placenta; and invasive placentation, is a leading cause of life-threatening…
- Trial name
- NCT06030479
- Testing
- Topical adrenaline, Warm saline
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Placenta Accreta
Efficacy of Hydrogen Peroxide ( H2O2) in Controlling Placental Site Bleeding in Caesarian Delivery for Placenta Previa / Accreta Spectrum ( PAS)
Placenta accreta spectrum (PAS), encompassing the terms placenta accreta, increta, and percreta; abnormally invasive placenta; morbidly adherent placenta; and invasive placentation, is a leading cause of life-threatening…
- Trial name
- NCT06030492
- Testing
- packing placental site with hydrogen peroxide soaked towels, normal Saline
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maternal; Procedure
Total Placenta Previa Associated With the Placenta Accreta Spectrum.
To assess the reliability of placental magnetic resonance imaging measurements in predicting peripartum hysterectomy and neonatal outcomes in patients with total placenta previa.
- Trial name
- PAS (NCT06219564)
- Testing
- Peripartum total abdominal hysterectomy (p-TAH), Cesarean Section (C/S), Neonatal mortality
- Where
- Turkey (Türkiye)
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Obstetric Anesthesia Problems, Placenta Accreta
Fibrinogen Concentrate and Placenta Acreta Spectrum
The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS.
- Trial name
- NCT05938062
- Testing
- the group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Placenta Accreta Spectrum
Evaluation of Different Surgical Approaches Used for Conservative Management of Placenta Accreta Spectrum in Sohag University Hospital
The objective of this study is to evaluate different intra-operative procedures to control bleeding in cases of PAS disorders aiming to determine the best procedure regarding maternal morbidity and mortality post-operatively, and…
- Trial name
- NCT05510076
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Placenta Accreta
Ligation of Anterior Internal Iliac Artery With Conservative Management of Partial or Focal Placenta Accreta Spectrum
The patients will be divided into 2 groups: Group (A) - Study group: Cases managed by lower segment resection with ligation of the anterior division of the internal iliac artery Group (B) - Control group: Cases managed by lower…
- Trial name
- NCT05471102
- Testing
- Study group: lower segment resection with ligation of the anterior division of the internal iliac artery, Control group: lower segment resection without ligation of the anterior division of the internal iliac artery
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bladder Injury, Complications; Cesarean Section
Cystoinflation to Prevent Bladder Injury in Obstetrics and Gynaecology Surgery
Part1:The healthy pregnant women with previous operative deliveries admitted for elective C-section will be counselled and conditioned informed consent will be taken to be included in either study group if dense pelvic adhesions…
- Conditions
- Bladder Injury, Complications; Cesarean Section, Adhesions Pelvic
- Trial name
- NCT04302545
- Testing
- Cystoinflation
- Where
- Pakistan
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Shazia Saaqib
Placenta Accreta Spectrum, Cesarean Hysterectomy
Early vs Late Bladder Dissection During CS Hysterectomy in Patients With PAS With Bladder Invasion
Thirty-six singleton pregnant women with PAS and bladder invasion; total anterior or anterolateral invasion, who were scheduled for cesarean hysterectomy were randomly assigned into two equal groups Group 1: included 18 pregnant…
- Trial name
- NCT05752513
- Testing
- Late bladder dissection, early bladder dissection
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pathophysiology of Placenta Accreta
Impact of Netrin-1 in the Pathophysiology of Placenta Accreta Spectrum
The main goal of this study is to assess the role of Netrin 1, neogenin and ZEB1 in PAS-associated invasion
- Trial name
- NCT04628169
- Testing
- no intervention applied
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Placenta Accreta Spectrum, Placenta Accreta / Percreta
Relaxin and Placental Volume in Placenta Accreta Spectrum
This retrospective case-control study investigated the potential role of circulating relaxin levels and estimated placental volumes (EPV) in the pathogenesis and diagnosis of placenta accreta spectrum (PAS) disorders.
- Trial name
- NCT06808165
- Testing
- relaxin
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital