Clinical trials: Plant-based Milk
Lactose Intolerants, Lactose Malabsorption
Milk Beta Caseins on Digestive Discomfort, Gastric Emptying
A1 and A2 β-casein are genetic variants of β-casein in cow's milk that differ by a single amino acid at position 67. Digestion of A1 β-casein may result in greater release of beta-casomorphin-7 (BCM-7), an opioid peptide that may…
- Conditions
- Lactose Intolerants, Lactose Malabsorption, Caseins
- Trial name
- Oral Naloxone (NCT07884123)
- Testing
- A1/A2 milk with oral naloxone, A1PF milk with oral naloxone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Purdue University
Lactose Intolerance
Comparing the Adaptation of Commercial Milk and A2 Milk in Lactose Maldigesters
Cow's milk contains two types of β-casein: A1 and A2. It is evident from human clinical trials that milk with A1 protein produces more hydrogen and symptoms of lactose intolerance.
- Trial name
- NCT05669274
- Testing
- Milk containing A1 and A2 beta-casein, Milk containing only A2 beta-casein
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue University
Metabolic Dysfunction-Associated Steatotic Liver Disease Infant Development
TUDCA in High-Risk Lactating Mothers Identified by Early Postpartum Milk Hydrophobicity Index
This is a randomized, double-blind, placebo-controlled Phase 2 proof-of-concept trial in mother-infant dyads. The study aims to evaluate the safety, tolerability, and biological effects of maternal oral tauroursodeoxycholic acid…
- Trial name
- MILK-HI-TUDCA (NCT07517276)
- Testing
- tauroursodeoxycholic acid (TUDCA)
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Protein Intolerance
A2 GUM Post-Market Effectiveness Study
This is a post-market, real-life effectiveness study of A2 growing up milk on toddlers' gut comfort.
- Trial name
- NCT03698058
- Testing
- Toddler milk
- Where
- China
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Obesity, Dyslipidemia
Soda and Milk Study
Much attention has been directed at the unhealthy effects of sugar-sweetened beverages (SSBs), as an increase in their consumption has paralleled the rise obesity rates.
- Trial name
- SAMS (NCT02094768)
- Testing
- Reduced Fat Milk, Sugar Sweetened Soda
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Breastfeeding, Human Milk
Comparison of Breast Milk Content in Mothers Using a Expressing Pump and Milking by Hand
The researchers planned this study to compare the effects of breast pumps, which are frequently used today, and manual milking after manual massage on the change in milk content when breast and breastfeeding problems develop.
- Trial name
- NCT05401123
- Testing
- milking pump
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Functional Gastrointestinal Disorders
Effect of Controlled Diet Combined With a Fermented Milk Product on Gas-related Symptoms
To select among different dietary and clinical conditions the most appropriate to assess the impact of a fermented milk product on gas-related symptoms
- Trial name
- FLATBACK (NCT02936713)
- Testing
- Fermented milk product with probiotics (FMPP)
- Where
- Spain
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Breast Milk
Influence of Pomegranate Juice Consumption on the Level of Antioxidants in Breast Milk
Many medicinal effects of Pomegranate juices are already known. Mainly known for its anti-viral, anti-bacterial and anti-oxide tendency of pomegranate juice.
- Trial name
- NCT01800110
- Testing
- pomegranate juice
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Preterm Infant Feeding Outcomes
Effect of Breast Milk Olfactory Stimulation
Breast milk olfactory stimulation will improve preterm infants' outcomes.
- Trial name
- BMOS (NCT06771882)
- Testing
- BMOS technique
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Muscle Damage
Sex Differences in Muscle Damage Following Resistance Exercise With or Without Milk Protein Ingestion
Purpose: To investigate the impact of milk protein ingestion on resistance exercise-induced muscle damage in untrained males and females.
- Trial name
- EIMD-MILK (NCT04986150)
- Testing
- Resistance exercise
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durham University
Peanut Allergy, Milk Allergy, Cow's
Investigating Modified Protocols of Oral Immunotherapy to Validate Efficacy and Safety
Protocols for Oral Immunotherapy (OIT) for the main food allergens have been recently incorporated in clinical practice for food allergies and their clinical benefits have been acknowledged in European and Canadian official…
- Conditions
- Peanut Allergy, Milk Allergy, Cow's, Egg Allergy
- Trial name
- IMPROVES (NCT06256146)
- Testing
- Food allergy desensitization / Oral Immunotherapy
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Muscular Hypertrophy
Resistance Training and Milk Supplementation
Post-resistance training high protein milk supplementation may be a viable method to elicit muscular gains. The investigators hypothesis is that high protein milk supplementation would improve skeletal regulatory markers…
- Trial name
- NCT04509297
- Testing
- high protein milk
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marymount University
Fatty Liver
A Study of Siliphos in Adults With Non-alcoholic Steatohepatitis (NASH)
The purpose of this study is to evaluate the dietary supplement Siliphos, which comes from milk thistle, to determine whether it is safe and well-tolerated in adults who have non-alcoholic steatohepatitis (NASH).
- Trial name
- NCT00443079
- Testing
- IdB 1016 (Siliphos)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Heather Patton
Formula Feeding of Healthy Full Term Infants, Breast Feeding of Healthy Full Term Infants
Impact of Infant Feeding on Newborn Metabolomic Profile
The purpose of this study is the evaluation with untargeted modalities, of the urine metabolomic profile in a group of infants fed with a standard formula, a group of infants fed with a formula supplemented with functional…
- Trial name
- NCT01606683
- Testing
- Infant formula with GOS, beta-palmitate, acidified milk, Standard infant formula without functional ingredients, No intervention
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Heinz Italia SpA
Low Milk Supply, Pre-diabetes
Metformin to Augment Low Milk Supply (MALMS) Study
Most new mothers in the United States will start off breastfeeding. For some mothers, despite following best practices, they are not able to meet their breastfeeding goals due to unexplained low milk supply.
- Conditions
- Low Milk Supply, Pre-diabetes, Insulin Resistance, Suppressed Lactation
- Trial name
- MALMS (NCT02179788)
- Testing
- Standard care, Metformin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Underweight
The Effect of Hormonal Contraceptives on Breast-milk Production and Infant Growth
The investigators propose a randomized clinical trial comparing the effect of 30 mcg ethinyl estradiol and LNG 150 combination oral contraceptive pills versus placebo, or LNG-IUS or Etonogestrel-releasing contraceptive implant…
- Trial name
- NCT01388582
- Testing
- LNG-IUS, Implanon, 30 mcg EE and 150 LNG oral contraceptive (Microvlar)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Infant, Very Low Birth Weight
Growth and Microbiome Development in Very Low Birth Weight Infants Fed Primarily Mother's Own Milk vs. Donor Human Milk
A study to compare growth, development of the intestinal bacterial environment, and other short term outcomes in groups of babies fed primarily their own mother's milk compared to those who receive primarily donor human milk.
- Trial name
- NCT02573779
- Testing
- Observational - no intervention
- Where
- 2 sites in United States
- Volunteers
- 125 people
- Sponsor
- Baylor College of Medicine
Healthy
Human Milk Nutrients and Infants' Health Outcomes in South China
The purpose of this study is to investigate the associations between human milk nutrients and infants' health outcomes in China.
- Trial name
- NCT05432180
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Huilian Zhu
Nutrition
Metabolic Signatures of Dairy Products Ingestion in Humans: Effect of Age
Despite the fact that dairy products are greatly consumed, it remains today very difficult to determine with a classical blood biochemical test whether a person has ingested a fresh fermented dairy product or just milk, while…
- Trial name
- FermentoMilk (NCT03500003)
- Testing
- Acute milk intake, Acute Yogurt intake
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Sergio Polakof
Constipation
Oat Milk for Laxation
This study intends to recruit 90-100 constipated participants aged 25-50 years, including an equal number of males and females, from the faculty and logistics staff of Capital Medical University.
- Trial name
- NCT07302542
- Testing
- oat milk
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
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