Clinical trials: Plaque Neovascularization
Carotid Artery Disease, Plaque Neovascularization
"In Vivo" Comparison in Human Carotid Atherosclerosis: Plaque Neovascularization
Atherosclerosis may initiate early in life and takes years to progress. This contrasts to the abrupt coronary or cerebrovascular events occurring following the transition from a stable to an unstable atherosclerotic plaque.
- Trial name
- PLAVASC (NCT02321410)
- Testing
- Contrast enhanced ultrasound of the carotid plaque, Dynamic contrast-enhanced carotid plaque MRI
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Ospedale San Giovanni Bellinzona
Carotid Atherosclerotic Disease
Supplementation of Lycopene in Carotid Atheroma
Stroke is the second leading cause of death worldwide. One of the causes of stroke which can be treated is narrowing of the carotid artery. Currently the only definite treatment option is surgery or endovascular treatment.
- Trial name
- SOLANUM (NCT01102504)
- Testing
- Ateronon
- Where
- United Kingdom
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Intraplaque Neovascularization Evaluated by Carotid Enhanced Ultrasound Well Reflect the Plaque Vulnerability
Serum Biomarker of Plaque Vulnerability and Contrast Ultrasound of Carotid Artery
No serum biomarker has qualified for clinical use until now. However several biomarkers, especially markers of inflammatory or proteolytic activity seem to promising in the identification of vulnerable plaques.
- Trial name
- NCT01842490
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Kyunghee University Medical Center
Atherosclerosis
Ultrasound and Other Images of Artery Blockages
Background: Treatments for partly blocked carotid arteries are determined by a person s symptoms and by tests that show how severe the blockage is.
- Trial name
- NCT01419574
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Carotid Atherosclerosis, Ultrasound
3D Contrast Enhanced Microvascular Ultrasound of Carotid Atherosclerosis for the Detection of Carotid Plaque Neo-Revascularisation.
Atherosclerotic plaques, the build-up of fatty materials within our arteries, can develop over a long period of time without causing any symptoms.
- Conditions
- Carotid Atherosclerosis, Ultrasound, Plaque Neovascularization
- Trial name
- Carotid Neo3D (NCT07298655)
- Testing
- 3D Contrast Enhanced Microvascular Carotid Ultrasound
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- London North West Healthcare NHS Trust
Carotid Stenosis, Carotid Artery Diseases
Ultrafast Ultrasound Imaging Assesment of Carotid Plaque Neovascularization
Stroke is the second leading cause of death in the Western world and the leading cause of major lifelong disability. About 15% of strokes are secondary to thrombosis or embolization of an unstable atheromatous carotid plaque.
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Carotid Atherosclerosis, Carotid Artery Plaque
- Trial name
- ULTRA-VASC (NCT04470687)
- Testing
- contrast enhanced ultrafast ultrasound imaging
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carotid Artery Diseases
The Changes in Carotid Plaque Neovascularization After Elovocumab Therapy
150 selected patients will be recruited, who have at least one atherosclerotic plaque in the carotid artery that is thicker than 2.0 mm and which is determined to be uniformly or predominantly echolucent by standard…
- Trial name
- NCT04423406
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zibo Central Hospital
Atherosclerosis, Stroke
3D/4D Ultrasound Contrast Enhanced Imaging (CEUS) for Carotid Plaque Vulnerability
Contrast enhanced 3D/4D (3 dimension/4 dimension) ultrasound (CEUS) provides visualization of the dynamic vascular features of the plaques, in a unique spatial format using three orthogonal planes and angiogram-like images.
- Trial name
- CEUS carotid (NCT02259257)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Diana Gaitini MD.
Carotid Artery Stenosis, Atherosclerosis
Contrast-enhanced Ultrasound (CE-US) and Magnetic Resonance Imaging (MRI): Evaluating Plaque Neovascularisation
The first goal of this study is to investigate whether CE-US is able to accurately identify and quantify neovascularisation in carotid artery plaques.
- Trial name
- NCT00677963
- Testing
- sulphur hexafluoride, gadopentate dimeglumine
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Maastricht University Medical Center