Clinical trials: Plaque Psoriasis.
Psoriasis
1404003_OpenPsori.PlaqueTest to Eval.Eff.of Diff.Comp. to Mapracorat
Evaluation of efficacy and safety of Mapracorat 0.1% ointment and 4 comparator ointments in male and female subjects 18 to 65 years with stable plaque-type psoriasis treated once daily 6 days a week for a maximum of 4 weeks.
- Trial name
- NCT03399526
- Testing
- Mapracorat (ZK 245186, BAY 86-5319), Prednicarbate 0.25% ointment, Clobetasol 0.05% ointment
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Bayer
Plaque Psoriasis
Efficacy and Safety of Roflumilast Cream 0.3% in Subjects With Plaque Psoriasis: a Phase 3 Study
This study is a multi-center, randomized, double-blind, vehicle-controlled phase III study to evaluate the efficacy, safety, and PK profile of roflumilast cream 0.3% in Chinese subjects ≥6 years of age with plaque psoriasis.
- Trial name
- NCT06648772
- Testing
- Roflumilast Cream 0.3%, Vehicle cream
- Where
- 31 sites in China
- Volunteers
- 190 people
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Psoriasis
Pentoxifylline Add-On Therapy for Mild-to-Moderate Plaque Psoriasis
This study will evaluate whether pentoxifylline, when used as an add-on treatment to standard topical therapy, is effective and safe for adults with mild-to-moderate plaque psoriasis.
- Trial name
- PTX-PSO (NCT07626788)
- Testing
- Pentoxifylline 400 mg Oral Tablet
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Wasuchon Chaichan
Psoriasis
An Efficacy and Safety Study of LYC-30937-EC in Subjects With Moderate Chronic Plaque-type Psoriasis
The objective of this Phase 2 trial is to determine the efficacy and safety of LYC-30937-EC in patients with moderate plaque-type psoriasis.
- Trial name
- NCT02872285
- Testing
- Drug: LYC-30937-EC
- Where
- 7 sites in United States
- Volunteers
- 33 people
- Sponsor
- Lycera Corp.
Chronic Plaque Psoriasis
Raptiva in Palm and Sole Psoriasis
The primary purpose of the study is to evaluate the safety and efficacy of Raptiva® compared to placebo in controlling moderate to severe chronic plaque psoriasis involving palms and/or soles scoring Palmo-plantar Pustular…
- Trial name
- NCT00972543
- Testing
- Efalizumab (Raptiva)
- Volunteers
- 6 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Chronic Plaque Psoriasis
Topical Vitamin B12 in Chronic Plaque Psoriasis
Objective: To test the efficacy and tolerability of a vitamin B12 cream for the treatment of chronic plaque psoriasis. Design: Multicenter, double-blind, randomized, placebo-controlled trial.
- Trial name
- NCT00350116
- Testing
- topical vitamin B12
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Ruhr University of Bochum
Psoriasis Vulgaris
An Exploratory Psoriasis Plaque Test Study With Different Dose Combinations of Calcipotriol Plus Betamethasone Dipropionate in the Daivobet® Gel Vehicle in Psoriasis Vulgaris
The purpose of this study is to evaluate the antipsoriatic effect of 5 different combinations of calcipotriol plus betamethasone dipropionate in Daivobet® gel vehicle in compared to Daivobet® gel in order to explore/find other…
- Trial name
- NCT01837576
- Testing
- Calcipotriol plus BDP gel in different doses
- Where
- France
- Volunteers
- 24 people
- Sponsor
- LEO Pharma
Acne, Atopic Dermatitis
Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.
- Conditions
- Acne, Atopic Dermatitis, Chronic Hand Eczema, Hidradenitis Suppurativa
- Trial name
- NCT05994976
- Testing
- Blood samples collection, Oral samples collection, Hair samples collection
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Plaque Psoriasis
Efficacy and Safety of ME3183 in Subjects With Moderate to Severe Plaque Psoriasis
The purpose of this study is to assess the efficacy and safety of ME3183 administered orally for moderate to severe plaque psoriasis in adults.
- Trial name
- NCT05268016
- Testing
- ME3183
- Where
- 27 sites in United States, Canada
- Volunteers
- 132 people
- Sponsor
- Meiji Pharma USA Inc.
Psoriasis
A Study to Test How Well Different Doses of BI 765250 Are Tolerated by People With a Skin Disease Called Plaque Psoriasis
This study is open to adults with plaque psoriasis. The main purpose of this study is to find out whether people with plaque psoriasis can tolerate a medicine called BI 765250.
- Trial name
- NCT05728489
- Testing
- BI 765250
- Where
- 5 sites in Bulgaria, Georgia and 2 more
- Volunteers
- 64 people
- Sponsor
- Boehringer Ingelheim
Psoriasis
A Prospective Multicenter Study for the Assessment of Treatment Patterns, Effectiveness and Safety of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis in a Real-world Setting in China
This non-interventional, prospective, multi-center study aims to provide short- and long- term treatment patterns, effectiveness, and safety of secukinumab in Chinese patients with moderate to severe plaque psoriasis (with and…
- Trial name
- UNMASK2 (NCT04894890)
- Testing
- secukinumab
- Where
- 42 sites in China
- Volunteers
- 1,002 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Plaque Psoriasis
Evaluate the Efficacy and Safety of One Course of Amevive in Taiwan Patients
An open-label, multicentre study to evaluate the efficacy and safety of one course of weekly intramuscular administration of Amevive in Taiwan patients with chronic plaque psoriasis
- Trial name
- NCT00422617
- Testing
- Alefacept (Amevive)
- Volunteers
- 40 people
- Sponsor
- Uni-Pharma
Plaque Psoriasis
A Comparison of 122-0551 Foam Versus Vehicle Foam in Subjects With Plaque Psoriasis (Study 310)
This Phase 3 study (Study 310) has been designed to determine and compare the efficacy and safety of 122-0551 Foam and Vehicle Foam applied twice daily for two weeks in subjects with plaque psoriasis.
- Trial name
- NCT02742441
- Testing
- 122-0551 Foam, Vehicle Foam
- Where
- 21 sites in United States
- Volunteers
- 409 people
- Sponsor
- Therapeutics, Inc.
Psoriasis (PsO)
A Phase 2 Study of HB0017 in Psoriasis Patients
This study is a randomized, double-blind phase 2 clinical trial aimed at exploring the efficacy, safety, and immunogenicity of HB0017 injection with different dosing regimens in the treatment of moderate to severe plaque…
- Trial name
- HB0017 (NCT06592274)
- Testing
- HB0017
- Where
- 18 sites in China
- Volunteers
- 206 people
- Sponsor
- Huabo Biopharm Co., Ltd.
Plaque Psoriasis
Fire Needle Therapy on Plaque Psoriasis With Blood Stasis Syndrome
This study was designed as a multicenter, randomized, single blinded and placebo-controlled clinical trial. The aim of the study is to evaluate the clinical efficacy, safety and control of recurrence rate of plaque psoriasis with…
- Trial name
- NCT03953885
- Testing
- Fire needle
- Where
- 5 sites in China
- Volunteers
- 92 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Plaque Psoriasis
A Comparison of 122-0551 Foam Versus Vehicle Foam in Subjects With Plaque Psoriasis
This Phase 3 study has been designed to determine and compare the efficacy and safety of 122-0551 Foam and Vehicle Foam applied twice daily for two weeks in subjects with plaque psoriasis.
- Trial name
- NCT02367911
- Testing
- 122-0551 Foam, Vehicle Foam
- Where
- 9 sites in United States
- Volunteers
- 144 people
- Sponsor
- Therapeutics, Inc.
Psoriasis
A Study of BMS-582949 in Patients With Moderate to Severe Plaque Psoriasis
The purpose of this clinical research study is to learn if BMS-582949 alone is an effective treatment for moderate to severe psoriasis. The safety of the drug and the effectiveness of each dose will also be studied.
- Trial name
- NCT00399906
- Testing
- BMS-582949
- Where
- 21 sites in Australia, Canada and 1 more
- Volunteers
- 99 people
- Sponsor
- Bristol-Myers Squibb
Psoriasis, Plaque-type Psoriasis
Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate-to-Severe Plaque-Type Psoriasis (Core Study)
The purpose of this study was to test if the drug apremilast was safe, if it helped improve psoriasis, and how well the participants tolerated it.
- Trial name
- NCT00773734
- Testing
- Apremilast 10mg, Apremilast 20mg, Apremilast 30 mg
- Where
- 35 sites in United States, Canada
- Volunteers
- 352 people
- Sponsor
- Amgen
Plaque Psoriasis
Study to Assess the Reliability of PASI Scoring Using Digital-Based Images
This is an open-labeled study to evaluate the reliability of digital photographs for the remote assessment of the disease severity of plaque psoriasis.
- Trial name
- NCT05835843
- Testing
- In-Person and Remote Disease Assessment
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Innovaderm Research Inc.
Psoriasis Vulgaris
Secukinumab Efficacy Without the Initial Loading Dose in Patients With Psoriasis
This was a retrospective, observational study. The objective of the study is investigate the efficacy and safety of secukinumab without the initial weekly loading dose in patients with chronic plaque psoriasis.
- Trial name
- NCT03828643
- Testing
- Secukinumab
- Where
- Italy
- Volunteers
- 156 people
- Sponsor
- Universita di Verona