AcneNCT05994976
Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers
An observational study of Acne and Atopic Dermatitis, run by Innovaderm Research Inc. at 1 site in Canada.
Trial summary
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Acne, Atopic Dermatitis, Chronic Hand Eczema
- What is being tested?
- Blood samples collection, Oral samples collection and Hair samples collection
- Type of treatment
- Pill or oral medicine, Surgery or procedure
- How many people
- 500 participants
- Where
- 1 siteCanada
- Study dates
- 17 Oct 2023to Aug 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Approximately 200 healthy volunteers and approximately 300 subjects with acne, atopic dermatitis (AD), chronic hand eczema (CHE), hidradenitis suppurativa (HS), palmoplantar pustulosis (PPP), and/or psoriasis will be included in this study.
Who may be able to join
- All subjects:
- Subject is willing to participate and is capable of giving informed consent. Note: Consent must be obtained prior to any study-related procedures.
- Subject must be willing to comply with all study procedures and must be available for the duration of the study.
- Healthy volunteers:
- Male or female subject aged 18 years or older, at the time of consent.
- Subject is in good general health, according to the investigator's judgment.
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- Subjects with Acne:
- Male or female subject aged 18 to 45 years old, inclusive, at the time of consent.
- Subjects with AD:
- Male or female subject aged 18 years or older, at the time of consent.
- Subject has clinically confirmed diagnosis of active AD, according to Hanifin and Rajka criteria.
- Subjects with CHE:
- Male or female subject aged 18 years or older, at the time of consent.
- Subject has at least a 6-month history of CHE before Screening (information obtained from medical chart or subject's physician, or directly from the subject).
- Subjects with HS:
- Male or female subject aged 18 years or older, at the time of consent.
- Subject has a clinically confirmed diagnosis of active HS with a disease duration of ≥ 6 months before screening as determined by the investigator through subject interview and/or review of the medical history.
- Subjects with PPP:
- Male or female subject aged 18 years or older at the time of consent.
- Subject has at least a 6-month history of PPP as defined by the presence of pustules on palms and/or soles, but without evidence of infection on palms and soles (information obtained from medical chart or subject's physician, or directly from the subject).
- Subjects with psoriasis:
- Male or female subject aged 18 years or older, at the time of consent.
Who cannot join
- All subjects:
- Subject is a female who is pregnant or who is planning to become pregnant during the study.
- Subject has a history of skin disease or presence of skin condition that, in the opinion of the investigator, would interfere with the study assessments.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Canada1 site, 1 recruiting
- Recruiting
Innovaderm Research Inc.
Montreal, Quebec, H2X 2V1
Valérie Piché Richard, MSc, 514-521-4285 ext. 159, vrichard@inderocro.com
About this study
Official title: Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers for Molecular Characterization of Inflammatory Skin Diseases
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.
Read the detailed description
This study is being conducted to collect samples from subjects with various skin conditions as well as healthy volunteers. Collected samples may be used for different analyses including, but not limited to, biomarker and gene expression analyses.
- Conditions
- Acne, Atopic Dermatitis, Chronic Hand Eczema, Hidradenitis Suppurativa, Plaque Psoriasis, Palmoplantar Pustulosis
- Being tested
- Blood samples collection, Oral samples collection, Hair samples collection, Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping), Skin surface material samples
- Medical subject headings
- Acne Vulgaris, Dermatitis, Atopic, Hidradenitis Suppurativa, Psoriasis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Blood samples collectionProcedure or surgery
biomarkers and optional genetic analysis
Oral samples collectionProcedure or surgery
biomarkers analysis
Hair samples collectionProcedure or surgery
biomarkers analysis
Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping)Procedure or surgery
biomarkers analysis
Skin surface material samplesProcedure or surgery
biomarkers analysis
Drainage fluid samples collectionProcedure or surgery
biomarkers analysis
Stool samples collectionProcedure or surgery
biomarkers analysis
| Study group | Role | What they receive |
|---|---|---|
| Healthy volunteers | Healthy adults Receives: Procedure: Blood samples collection; Procedure: Oral samples collection; Procedure: Hair samples collection; Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping); Procedure: Skin surface material samples; Procedure: Drainage fluid samples collection; Procedure: Stool samples collection | |
| Acne | Adult subjects aged 18 to 45 years old with acne Receives: Procedure: Blood samples collection; Procedure: Oral samples collection; Procedure: Hair samples collection; Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping); Procedure: Skin surface material samples; Procedure: Drainage fluid samples collection; Procedure: Stool samples collection | |
| AD | Adult subjects with Atopic Dermatitis (AD) Receives: Procedure: Blood samples collection; Procedure: Oral samples collection; Procedure: Hair samples collection; Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping); Procedure: Skin surface material samples; Procedure: Drainage fluid samples collection; Procedure: Stool samples collection | |
| CHE | Adult subjects with Chronic Hand Eczema (CHE) Receives: Procedure: Blood samples collection; Procedure: Oral samples collection; Procedure: Hair samples collection; Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping); Procedure: Skin surface material samples; Procedure: Drainage fluid samples collection; Procedure: Stool samples collection | |
| HS | Adult subjects with Hidradenitis suppurativa (HS) Receives: Procedure: Blood samples collection; Procedure: Oral samples collection; Procedure: Hair samples collection; Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping); Procedure: Skin surface material samples; Procedure: Drainage fluid samples collection; Procedure: Stool samples collection | |
| PPP | Adult subjects with Palmoplantar pustulosis (PPP) Receives: Procedure: Blood samples collection; Procedure: Oral samples collection; Procedure: Hair samples collection; Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping); Procedure: Skin surface material samples; Procedure: Drainage fluid samples collection; Procedure: Stool samples collection | |
| Psoriasis | Adult subjects with Psoriasis Receives: Procedure: Blood samples collection; Procedure: Oral samples collection; Procedure: Hair samples collection; Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping); Procedure: Skin surface material samples; Procedure: Drainage fluid samples collection; Procedure: Stool samples collection |
What is being measured
The primary outcome is the main question the study is designed to answer.
Untargeted biomarker approach with gene expression profile of skin samples
Measured: Day 1
Exploratory biomarker and gene expression analyses.
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Aug 2023
- Study start17 Oct 2023
- Primary completionAug 2028 (estimated)
- Study completionAug 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AcneStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Innovaderm Research Inc.
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Robert Bissonnette, MD, Principal investigator, Innovaderm Research Inc.
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05994976
- Sponsor's protocol ID
- INNO-5034
- Status last verified
- Oct 2026
- First submitted
- 9 Aug 2023
- Last updated
- 28 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers for Molecular Characterization of Inflammatory Skin Diseases
- ClinicalTrials.gov ID
- NCT05994976
- Acronym / sponsor ID
- INNO-5034
- Conditions
- Acne, Atopic Dermatitis, Chronic Hand Eczema, Hidradenitis Suppurativa, Plaque Psoriasis, Palmoplantar Pustulosis
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 500 participants (estimated)
- Lead sponsor
- Innovaderm Research Inc.University, hospital or other
- Study start
- 17 Oct 2023 (actual)
- Primary completion
- Aug 2028 (estimated)
- Study completion
- Aug 2028 (estimated)
- First posted
- 16 Aug 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.
Detailed description
This study is being conducted to collect samples from subjects with various skin conditions as well as healthy volunteers. Collected samples may be used for different analyses including, but not limited to, biomarker and gene expression analyses.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 7
| Arm | Type | Receives |
|---|---|---|
| Healthy volunteers | – | Procedure: Blood samples collection, Procedure: Oral samples collection, Procedure: Hair samples collection, Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping), Procedure: Skin surface material samples, Procedure: Drainage fluid samples collection, Procedure: Stool samples collectionHealthy adults |
| Acne | – | Procedure: Blood samples collection, Procedure: Oral samples collection, Procedure: Hair samples collection, Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping), Procedure: Skin surface material samples, Procedure: Drainage fluid samples collection, Procedure: Stool samples collectionAdult subjects aged 18 to 45 years old with acne |
| AD | – | Procedure: Blood samples collection, Procedure: Oral samples collection, Procedure: Hair samples collection, Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping), Procedure: Skin surface material samples, Procedure: Drainage fluid samples collection, Procedure: Stool samples collectionAdult subjects with Atopic Dermatitis (AD) |
| CHE | – | Procedure: Blood samples collection, Procedure: Oral samples collection, Procedure: Hair samples collection, Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping), Procedure: Skin surface material samples, Procedure: Drainage fluid samples collection, Procedure: Stool samples collectionAdult subjects with Chronic Hand Eczema (CHE) |
| HS | – | Procedure: Blood samples collection, Procedure: Oral samples collection, Procedure: Hair samples collection, Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping), Procedure: Skin surface material samples, Procedure: Drainage fluid samples collection, Procedure: Stool samples collectionAdult subjects with Hidradenitis suppurativa (HS) |
| PPP | – | Procedure: Blood samples collection, Procedure: Oral samples collection, Procedure: Hair samples collection, Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping), Procedure: Skin surface material samples, Procedure: Drainage fluid samples collection, Procedure: Stool samples collectionAdult subjects with Palmoplantar pustulosis (PPP) |
| Psoriasis | – | Procedure: Blood samples collection, Procedure: Oral samples collection, Procedure: Hair samples collection, Procedure: Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping), Procedure: Skin surface material samples, Procedure: Drainage fluid samples collection, Procedure: Stool samples collectionAdult subjects with Psoriasis |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Approximately 200 healthy volunteers and approximately 300 subjects with acne, atopic dermatitis (AD), chronic hand eczema (CHE), hidradenitis suppurativa (HS), palmoplantar pustulosis (PPP), and/or psoriasis will be included in this study.
Key inclusion criteria (22 listed)
- Subject is willing to participate and is capable of giving informed consent. Note: Consent must be obtained prior to any study-related procedures.
- Subject must be willing to comply with all study procedures and must be available for the duration of the study.
- Male or female subject aged 18 years or older, at the time of consent.
- Subject is in good general health, according to the investigator's judgment.
- Male or female subject aged 18 to 45 years old, inclusive, at the time of consent.
Key exclusion criteria (3 listed)
- Subject is a female who is pregnant or who is planning to become pregnant during the study.
- Subject has a history of skin disease or presence of skin condition that, in the opinion of the investigator, would interfere with the study assessments.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Blood samples collectionbiomarkers and optional genetic analysis | Procedure or surgery | AD, Acne, CHE, HS, Healthy volunteers, PPP, Psoriasis |
| Oral samples collectionbiomarkers analysis | Procedure or surgery | AD, Acne, CHE, HS, Healthy volunteers, PPP, Psoriasis |
| Hair samples collectionbiomarkers analysis | Procedure or surgery | AD, Acne, CHE, HS, Healthy volunteers, PPP, Psoriasis |
| Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping)biomarkers analysis | Procedure or surgery | AD, Acne, CHE, HS, Healthy volunteers, PPP, Psoriasis |
| Skin surface material samplesbiomarkers analysis | Procedure or surgery | AD, Acne, CHE, HS, Healthy volunteers, PPP, Psoriasis |
| Drainage fluid samples collectionbiomarkers analysis | Procedure or surgery | AD, Acne, CHE, HS, Healthy volunteers, PPP, Psoriasis |
| Stool samples collectionbiomarkers analysis | Procedure or surgery | AD, Acne, CHE, HS, Healthy volunteers, PPP, Psoriasis |
Primary outcome
Untargeted biomarker approach with gene expression profile of skin samples
Time frame: Day 1
Exploratory biomarker and gene expression analyses.
Time frame: Day 1
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Robert Bissonnette, MD principal investigator
Innovaderm Research Inc.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Acne and Atopic Dermatitis, run by Innovaderm Research Inc. at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 22 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Julie Bedoucha, MSc (514-521-4285 ext. 253, jbedoucha@innovaderm.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Untargeted biomarker approach with gene expression profile of skin samples (time frame: Day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Oct 2026.