Clinical trials: Plaque Reduction
Gingival Bleeding, Dental Plaque
Efficacy of Dental Hygiene Aids in Reducing Gingival Bleeding and Plaque Among Orthodontic Patients.
Adult orthodontic patients aged 18-30 were included in a randomised, single-blind clinical research using a split-mouth design at a dental clinic. Both the Waterpik® and the Super-Floss® water flossers are manufactured by Oral-B.
- Trial name
- NCT06554938
- Testing
- water pik, Super floss
- Where
- United Arab Emirates
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ajman University
Periodontitis
Interdental Plaque Reduction and Periodontitis
To determine the efficacy of four different oral hygiene protocols involving adjunctive interdental cleaning devices in periodontal patients in terms of plaque and gingival inflammatory scores.
- Trial name
- NCT04527913
- Testing
- Interdental Oral Hygiene Instruction (Int-OHI), One session of professional supragingival scaling and polishing, Oral Hygiene Instruction (OHI)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Healthy, Hygiene
Oral Hygiene Tools for Biofilm Removal Around Implants
The objective of this clinical trial is to determine which interproximal hygiene device is most effective at eliminating dental plaque on implants.
- Conditions
- Healthy, Hygiene, Biofilm Removal
- Trial name
- NCT06697210
- Testing
- • Dental Floss (Vitis®, Dentaid, Barcelona, Spain)., • Superfloss (Oral B®, Procter & Gamble, USA), • Oral irrigator (Waterpick®, Water Pik, Inc., CO., USA)
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Gingivitis and Periodontal Diseases
Evaluation of Toothbrush Bristles
The goal of this randomized clinical trial is to investigate two different types of toothbrush bristles. The main questions it aims to answer are the effects of two different bristle types on: how much plaque is on the teeth how…
- Trial name
- NCT07306026
- Testing
- Toothbrush with tapered bristles, Toothbrush with end-rounded bristles
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Gingivitis, Dental Plaque
The Effect of Mouthrinses Containing Bamboo Salt, Magnolia Bark and Centella Asiatica on Reducing Plaque and Gingivitis
This study aims to evaluate the effect of novel mouthrinse formulations containing bamboo salt, magnolia bark and centella asiatica extracts on gingivitis and dental plaque.
- Trial name
- NCT03047798
- Testing
- Mouthrinse
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Acute Coronary Syndrome
Effectiveness of Thrombus Aspiration in Plaque Reduction for Patients With Acute Coronary Syndromes
Although successful, percutaneous coronary interventions (PCI) with stent implantation may be hampered by periprocedural myocardial necrosis.
- Trial name
- REMNANT (NCT01342848)
- Where
- 3 sites in Italy
- Volunteers
- 76 people
- Sponsor
- Raffaele De Caterina
Plaque, Gingivitis
The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis.
Qualified subjects will be enrolled and randomly assigned to either of the two study groups based on their initial Plaque and Gingivitis scores.
- Trial name
- NCT06427499
- Testing
- Stannous fluoride toothpaste, Colgate Cavity Protection Toothpaste
- Where
- Thailand
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Carotid Plaques
Vitamin K2 for Reduction the Calcium at Carotid Bifurcation in Patients With Subcritical Lesions
Clinical study single center, prospective, randomized, controlled (vs. no supplement), open-label, blinded assessor (the doctor who will perform the Doppler ultrasound at 6 and 12 months will not know the treatment given to the…
- Trial name
- NCT02970084
- Testing
- Nutraceutical product based on vitamin K2 (PLAK2)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Scientific Institute San Raffaele
Human Immunodeficiency Virus (HIV), Cardiovascular Risk Factor
Reducing Systemic Inflammation in People on Antiretroviral Therapy
This randomized, open-label clinical trial will evaluate whether adding fostemsavir to current antiretroviral therapy can reduce the risk of cardiovascular disease in people with well-controlled HIV.
- Trial name
- RESTART (NCT07030920)
- Testing
- Fostemsavir
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Toothbrushing, Periimplant Diseases
Manual Versus Sonic-powered Toothbrushing for Plaque Reduction in Patients with Peri-implant Mucositis
Aim: To compare the effect of manual and sonic-powered toothbrushing on biofilm control in patients with peri-implant mucositis.
- Trial name
- NCT06800625
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Hacettepe University
Gingivitis
Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste
The objective of this study is to evaluate the clinical efficacy of a toothpaste containing stannous fluoride as compared to Colgate Fluoride Toothpaste in reducing plaque and gingivitis - a three- month study.
- Trial name
- CP_Total (NCT04033575)
- Testing
- Colgate Total SF, Colgate Cavity Protection toothpaste
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque, Gingivitis
The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis
A clinical research study design to compare the effectiveness of a battery toothbrush and dentifrice in reducing gingivitis and dental plaque in adults.
- Trial name
- NCT07224828
- Testing
- Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste
- Where
- Puerto Rico
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque and Gingivitis
The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis
This is a six (6) month, double-blind, parallel, controlled clinical trial utilizing one hundred and sixty (160) adults to evaluate the reduction of dental plaque and gingivitis.
- Trial name
- NCT02243046
- Testing
- Control toothpaste, Experimental toothpaste, Active Comparator
- Where
- Dominican Republic
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Plaque, Dental
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
The 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the stannous fluoride containing toothpaste (SNAP) compared to Colgate Cavity Protection Toothpaste after 3 and 6 months of…
- Trial name
- NCT06300866
- Testing
- Test, Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque, Dental, Gingivitis
To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis.
Triple Blinded Randomized Clinical trial study to assess the efficacy of two brushing regimens: 1) a toothpaste containing stannous fluoride and a standard manual toothbrush as compared to 2) a regular fluoride toothpaste and…
- Trial name
- NCT07605338
- Testing
- Colgate SNaP Total 10/10, 1.5 Taurate, Colgate Great Regular Flavor Toothpaste, Flat Trimmed Extra Clean TB
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Obstructive Coronary Artery Disease, Coronary Artery Disease
YELLOW II Study: Reduction in Coronary Yellow Plaque, Lipids and Vascular Inflammation by Aggressive Lipid Lowering
Coronary artery disease (CAD) remains a leading cause of death in most countries. It is well known that the reduction of cholesterol levels by statin therapy is associated with significant decreases in plaque burden.
- Trial name
- NCT01837823
- Testing
- rosuvastatin
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gingival Inflammation and Bleeding, Dental Plaque
Clinical Efficacy Evaluation of Three Dentifrices
Clinical study to evaluate and compare the efficacy of two baking soda containing dentifrices, containing 20% and 35% baking soda, to a non-baking soda dentifrice for their ability to reduce gingivitis and plaque following…
- Trial name
- NCT03988374
- Testing
- Dentifrices
- Where
- Canada
- Volunteers
- 319 people
- Sponsor
- Church & Dwight Company, Inc.
Plaque, Dental, Caries, Dental
Livionex on Reducing Plaque Accumulation and Improving Oral Health in Children
This is an investigator initiated randomized double-blind pilot study at the UCSF Pediatric Dental Clinics to compare effectiveness of a new toothpaste Livionex Dental Gel with a standard children's toothpaste containing 1500 ppm…
- Conditions
- Plaque, Dental, Caries, Dental, Oral Hygiene
- Trial name
- NCT04368533
- Testing
- Livionex Dental Gel, A standard children's toothpaste containing 1500 ppm fluoride
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gingivitis, Plaque
Safety and Efficacy of the ToothWave -12 Weeks Calculus Study
The objective of the study is to evaluate the safety and efficacy of the home-use device Silk'n toothbrush (ToothWave) for the improvement in dental health through the reduction of plaque, gingivitis, and calculus.
- Conditions
- Gingivitis, Plaque, Calculus, Dental
- Trial name
- NCT04092075
- Testing
- RF-utilizing powered toothbrush
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Gingivitis
A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 Weeks
The purpose of this clinical study is to investigate the efficacy of a dentifrice containing 0.454 percent (%) weight by weight (w/w) stannous fluoride (SnF2), on gingivitis treatment and plaque reduction, compared to a regular…
- Trial name
- NCT06143670
- Testing
- Stannous fluoride toothpaste, Sodium fluoride toothpaste
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- HALEON