Clinical trials: Plaque Removal
Peri Implantitis
a Randomized Clinical Trial Evaluating Plaque Removal Around Dental Implants
This aim of this study is to compare different oral hygiene aids for the ability to remove plaque in patients who went through dental implant treatment and are currently on a maintenance program at the Graduate Periodontal…
- Trial name
- NCT02091609
- Testing
- dental interproximal brush, dental floss
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Dental Plaque
Efficacy of Three Experimental Toothpastes to Remove Plaque
The Dose response of three experimental toothpastes (test product 1, test product 2 and test product 3) to remove plaque after a single brushing, compared to a positive control and negative control dentifrice will be evaluated.
- Trial name
- NCT02992691
- Testing
- 20% w/w sodium bicarbonate, 35% w/w sodium bicarbonate, 50% w/w sodium bicarbonate
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Calculus, Dental, Periodontal Diseases
Development of a New Toothpaste for the Removal of Dental Calculus.
Periodontal disease is amongst the most prevalent oral diseases worldwide and in North America. According to the 2007/09 Canadian Health Measures Survey, 16% of Canadian adults and 24% of older adults, 60 to 79 years of age, were…
- Conditions
- Calculus, Dental, Periodontal Diseases, Periodontal Inflammation
- Trial name
- NCT04381403
- Testing
- Bio-descaling D-Tart toothpaste, Crest® toothpaste
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Faleh Tamimi
White Spot Lesions, Proximal Caries
Labial White Spot Lesions and Proximal Caries Development in Orthodontic Patients Using Clear Aligners Versus Traditional Braces.
This randomized clinical trial evaluates the risk of developing early tooth decay in patients undergoing orthodontic treatment with either traditional fixed braces or clear aligners.
- Conditions
- White Spot Lesions, Proximal Caries, Oral Hygiene in Orthodontic Patients, Plaque Removal
- Trial name
- NCT07550179
- Testing
- Fixed pre-adjusted edgewise orthodontic appliance, Clear aligner therapy
- Where
- United Arab Emirates
- Volunteers
- 24 people
- Sponsor
- University of Sharjah
Tooth Decay, Cavities of Teeth
Plaque Removal Effectiveness of a Flossing Device Compared to the Conventional Flossing in Adults
Objective: To evaluate the effectiveness in plaque removal of the new device; Dental floss holders and compare the results to the conventional way of flossing.
- Conditions
- Tooth Decay, Cavities of Teeth, Gingivitis, Plaque
- Trial name
- NCT06318819
- Testing
- Dental Floss Holders
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maha A. Bahammam
Peri-Implant Health
Plaque and Bleeding on Probing Around Implants Supporting Fixed Full-Arch Dental Prostheses
This observational study examines plaque, hard deposits (calculus), and gum bleeding around dental implants supporting fixed full-arch dental prostheses.
- Trial name
- NCT07898956
- Testing
- Prosthetic Maintenance History
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nicola Alberto Valente, DDS, MS, PhD
Dental Caries, Dental Plaque Accumulation
Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal
The study investigates the effectiveness of a 45°-cut miswak for plaque removal compared to a toothbrush in children and assesses their preferences for these tools.
- Trial name
- NCT07409610
- Testing
- Miswak, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Chronic Plaque Psoriasis
TRUST Study: Raptiva ® in Hand & Foot Psoriasis
To evaluate the safety and efficacy of Raptiva ® compared with placebo to control chronic moderate to severe plaque psoriasis involving the hands and/or feet scoring Physician's Global Assessment (PGA - H\&F) greater-than or…
- Trial name
- TRUST (NCT00739882)
- Testing
- Efalizumab - anti CD11a recombinant human monoclonal antibody
- Where
- Austria
- Volunteers
- 76 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Gingivitis
A Proof-of-principle Clinical Study Investigating the Efficacy of an Experimental Dentifrice Containing Sodium Bicarbonate and Sodium Hyaluronate on Gingivitis
The aim of this study is to develop a daily use toothpaste containing sodium bicarbonate, sodium hyaluronate and sodium fluoride with the intention of providing improved/ fast gum healing.
- Trial name
- NCT04737538
- Testing
- Experimental Dentrifrice, Positive control dentifrice, Negative control dentifrice
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy, Hygiene
Oral Hygiene Tools for Biofilm Removal Around Implants
The objective of this clinical trial is to determine which interproximal hygiene device is most effective at eliminating dental plaque on implants.
- Conditions
- Healthy, Hygiene, Biofilm Removal
- Trial name
- NCT06697210
- Testing
- • Dental Floss (Vitis®, Dentaid, Barcelona, Spain)., • Superfloss (Oral B®, Procter & Gamble, USA), • Oral irrigator (Waterpick®, Water Pik, Inc., CO., USA)
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peripheral Arterial Disease, Claudication
Study of SilverHawk®/TurboHawk® in Lower Extremity Vessels (DEFINITIVE™ LE)
The purpose of the study is to evaluate the intermediate and long-term effectiveness of stand-alone atherectomy treatment of peripheral arterial disease in the legs.
- Conditions
- Peripheral Arterial Disease, Claudication, Critical Limb Ischemia
- Trial name
- NCT00883246
- Testing
- SilverHawk & TurboHawk Peripheral Plaque Excision System
- Volunteers
- 800 people
- Sponsor
- Medtronic Endovascular
Plaque Induced Gingivitis
Comparative Effect of Chewing Sticks and Toothbrushing on Plaque Removal and Gingival Health
The purpose of the proposed study is to compare the effect of chewing sticks (Miswak) and the toothbrushes on plaque removal and gingival health.
- Trial name
- NCT01336179
- Testing
- Salvadora persica, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Taibah University
Dental Calculus
Testing if Tartarase Can Remove Dental Tartar
This study was designed to find our whether a novel toothpaste containing safe digestive enzymes (Tartarase) was able to remove pre-existing dental tartar when compared to a well-known toothpaste (Crest).
- Trial name
- NCT06139835
- Testing
- Tartarase
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pontis Biologics, Inc.
Tooth Plaque
Comparison Between Modified Bass and Horizontal Brushing Techniques
The goal of this observational study is to determine mean plaque scores to compare the effectiveness after using modified bass and horizontal brushing technique in undergraduate dental students.
- Trial name
- NCT05734456
- Where
- Pakistan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Oral Plaque Biofilm
University of New Mexico Dental Hygiene
To evaluate the efficacy of flossing in the removal of oral plaque biofilm.
- Trial name
- UNM (NCT03876353)
- Testing
- Floss
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Dental Plaque, Toothbrushing
Efficacy of an U-shape Automatic Electric Toothbrush in Plaque Removal
Over time, many different types of manual and electric toothbrushes have been produced. A systematic review has shown that some electric toothbrushes are more effective at removing bacterial plaque than manual toothbrushes.
- Trial name
- NCT04119583
- Testing
- U-shape Automatic Electric Toothbrush, Usual home toothbrushing procedure, Conventional Electric Toothbrush
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florence
Plaque Removal
Comparison of New and 3-Month-Old Toothbrush in the Removal of Plaque in Children
This study aimed to validate or invalidate non-inferiority in the plaque removal efficacy of old versus new toothbrushes in the hands of 7-9 year old children.
- Trial name
- NCT00836784
- Testing
- old toothbrush, New tooth brush
- Where
- Iran
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Dental Plaque
Ability of Four Toothpastes to Remove Plaque
The aim of this study is to evaluate and compare the plaque removal efficacy of four experimental toothpastes following a single timed brushing.
- Trial name
- NCT03285984
- Testing
- 67% Sodium Bicarbonate with 6 herbs plus 923parts per million (ppm) Sodium Fluoride, 67% Sodium Bicarbonate without herbs plus 923 ppm Sodium Fluoride, 62% Sodium Bicarbonate with 6 herbs and 5% w/w silica plus 923 ppm Sodium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Plaque, Dental
The Effectiveness of the Water Jet Device in Removing Dental Plaque Around Orthodontic Braces in Adolescents
The aim of this study was to evaluate the effectiveness of the water jet in removing dental plaque around the orthodontic braces in adolescents.
- Trial name
- NCT06098976
- Testing
- Water Jet, Manual toothbrush
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Damascus University
White Spot Lesion of Tooth, Gingival Inflammation
EFFECTIVENESS of WATER FLOSS in PLAQUE REMOVAL and PREVENTION of WHITE SPOT LESIONS in ORTHODONTIC PATIENTS: a RANDOMISED CONTROLLED CLINICAL TRIAL
This clinical trial aims to learn if water floss is as efficient as other interdental cleaning tools and can prevent plaque accumulation and white spot lesions (WSLs) in orthodontic patients.
- Conditions
- White Spot Lesion of Tooth, Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- WATER FLOSS (NCT06752291)
- Testing
- water flosser
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Malaya