Clinical trials: Plasma Exchange
Frailty, Plasma Exchange
Human Albumin Combined With Plasma Exchange for Frailty Intervention
Background Frailty is an age-related syndrome characterized by reduced physiological reserve, decreased stress tolerance and multisystem functional decline in the elderly, which markedly increases the risks of falls…
- Trial name
- NCT07836127
- Testing
- Plasma Exchange, 5% human albumin, Intravenous immunoglobulin (IVIG)
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Experience With Therapeutic Plasma Exchange in the Pediatric Nephrology Unit
Experience With Therapeutic Plasma Exchange in the Pediatric Nephrology Unit of Sohag University Hospital
Plasmapheresis also known as a therapeutic plasma exchange (TPE) TPE is an extracorporeal blood purification technique designed for the removal of large-molecular-weight substances.
- Trial name
- NCT07158463
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Sohag University
Therapeutic Plasma Exchange, Covid19
RescuE pLAsma eXchange in Severe COVID-19
The spectrum of coronavirus disease 2019 (COVID-19) ranges from asymptomatic infection to acute respiratory distress syndrome ("ARDS") and patient death.
- Trial name
- RELAX (NCT04685655)
- Testing
- Therapeutic plasma exchange
- Where
- 3 sites in Germany
- Volunteers
- 67 people
- Sponsor
- Heidelberg University
Therapeutic Plasma Exchange
Comparison Between Centrifugation Based and Membrane Based Plasma Exchange
This study aims at comparing centrifugation based therapeutic plasma exchange (cTPE) versus membrane based therapeutic plasma exchange (mTPE) as regards performance, effectiveness and adverse events in patients indicated for TPE.
- Trial name
- NCT06652516
- Testing
- plasma exchange
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Therapeutic Plasma Exchange, Anticoagulant Therapy
Evaluation of Complication Rates Using Filter vs. Centrifuge and Heparin vs. Citrate Anticoagulation
Despite its growing use across the world, and similar efficacy, filter-based therapeutic plasma exchange (TPE) continues to be used less often that centrifuge-based TPE.
- Trial name
- NCT04351438
- Testing
- Active Comparator: centrifuge TPE with citrate, Active Comparator: Filter TPE with heparin, Active comparator: Filter TPE with citrate
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Alabama at Birmingham
Therapeutic Plasma Exchange
TPE in Rennes Hospital
To assess the indications, tolerance and side effects of therapeutic plasma exchange (TPE) performed at a University Hospital over 8 years
- Trial name
- COMPLASMA (NCT03888417)
- Testing
- Therapeutic plasma exchange (TPE)
- Where
- France
- Volunteers
- 190 people
- Sponsor
- Rennes University Hospital
Therapeutic Plasma Exchange
IMPACT OF THERAPEUTIC PLASMA EXCHANGE ON ACQUIRED VACCINAL ANTI-SARS-CoV-2 ANTIBODIES.
Context: Therapeutic plasma exchange is an extracorporeal blood purification technique that removes pathogenic substances (including antibodies) from plasma. This technique also combines an immunomodulatory effect.
- Trial name
- NCT05191394
- Testing
- Evolution of antibodies titre
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Plasma Exchange
A Randomized Trial Examining Plasma Exchange Using the Becton Dickinson (BD) Catheter In an Outpatient Apheresis Unit
This is a randomized pilot study of therapeutic apheresis procedures (TAP) using the current standard of care catheter (SOC) vs the BD Nexiva Diffusics Catheter. It is a single blinded, randomized study.
- Trial name
- REPLACE (NCT04253756)
- Testing
- 20-gauge BD Nexiva Diffusics
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Texas Southwestern Medical Center
Clotting Disorder Due to Plasma Exchange Therapy, Humoral Rejection After Kidney Transplantation
Fibrinogen as a Surrogate for Global Haemostasis in Plasma Exchange
Plasma exchange is a frequently used therapy in many antibody-mediated disorders, such as humoral rejection after kidney transplantation.
- Trial name
- NCT02095821
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- Hannover Medical School
Hepatic Failure, Plasma Exchange
The Plasma Diafiltration Therapy of Hepatic Failure
At present, there is no comparative study between the simple plasma exchange and plasma diafiltration (PDF), and no further exploration of optimal plasma dose in PDF treatment.
- Trial name
- NCT03560414
- Testing
- simple plasma exchange, conventional PDF treatment group, less plasma PDF treatment group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fuzhou General Hospital
Plasma Exchange, Autonomic Failure
Plasma Exchange for Autoimmune Autonomic Failure
This study will explore whether an antibody is influencing the autonomic nervous system, and if its removal will eliminate signs and symptoms of failure in that system.
- Trial name
- NCT00359346
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)