Clinical trials: Plasmodium Falciparum
Malaria
A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265
This is a single-centre, open-label, dose finding study using induced blood stage malaria (IBSM) infection to characterize the pharmacodynamic interaction between OZ439 and DSM265, administered around 120 minutes apart for…
- Trial name
- OZ/DSMCombo (NCT02389348)
- Testing
- DSM265, OZ439
- Where
- Australia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Medicines for Malaria Venture
Malaria
Malaria Challenge in Healthy Volunteers
The purpose of this study is to determine if sterile, protective immunity to malaria can be induced by malaria parasite exposure limited to the early liver stage of the parasite lifecycle.
- Trial name
- ITV (NCT01500980)
- Testing
- P. falciparum infection, Chloroquine, Primaquine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital