Clinical trials: Platelet Rich Fibrin
Platelet Rich Fibrin, Platelet Rich Plasma Injection
Injectable Platelet Rich Fibrin Versus Platelet Rich Plasma Injection in Degenerative Temporomandibular Joint
The study aimed to compare the efficacy of injectable platelet rich fibrin (I-PRF) versus platelet rich plasma (PRP) injection in degenerative temporomandibular joint (TMJ).
- Conditions
- Platelet Rich Fibrin, Platelet Rich Plasma Injection, Degenerative Temporomandibular Joint
- Trial name
- NCT07078006
- Testing
- Platelet Rich Fibrin, Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nasser Institute For Research and Treatment
Wound Heal
Effect of A-PRF After Removal of Wisdom Teeth
To evaluate the healing effect of advanced platelet-rich fibrin (blood clot charged with growth factors) taken from the patient own blood on the extraction site.
- Trial name
- A-PRF (NCT03703479)
- Testing
- autologous blood clot made from the patient own clot without any additive
- Where
- Saudi Arabia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Pressure Ulcer
A Prospective, Randomized Clinical Trial of PRP Concepts Fibrin Bio-Matrix in Chronic Non-Healing Pressure Ulcers
To assess the efficacy of the PRP Concepts Fibrin Bio-Matrix and compare its performance with usual and customary practice for the treatment of chronic non-healing pressure ulcers (PU).
- Trial name
- NCT02312570
- Testing
- PRP Concepts Fibrin Bio-Matrix, Usual and Customary Practice
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- PRP Concepts, LLC
Periodontitis
Bone Morphogenetic Protein-2 In Grade II Furcation Defects.
The present study evaluated clinically and radiographically the regenerative potential of rhBMP-2 in absorbable sponge and PRF in Grade II furcation.
- Trial name
- NCT04372420
- Testing
- RhBMP-2 absorbable sponge in grade II furcation, PLATELET RICH FIBRIN in grade II furcation
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Wound Healing
Effect of Leucocyte- and Platelet-Rich Fibrin on Palatal Wound Healing After Free Gingival Graft Harvesting
Autogenous palatal free gingival graft harvesting presents challenges for patients due to the increased risk of postoperative morbidity related to a second intraoral surgical wound that heals with secondary intention.
- Trial name
- NCT06777069
- Testing
- Leucocyte and platelet rich fibrin membrane application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Istanbul Medipol University Hospital
Healthy Volunteers Only
Efficacy of Buccal Pad of Fat, Advanced Platelet Rich Fibrin, Fibrin Glue and Oxidized Cellulose Plug in Management of Oro-Antral Communication, Comparative Clinical Study
Evaluation of the efficacy of different treatment protocols in the management of Oro-Antral Communications.
- Trial name
- OAC (NCT06220877)
- Testing
- Buccal Pad of Fat, A-PRF, fibrin glue
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- October 6 University
Interdental Papilla Loss
Clinical Evaluation of Hyaluronic Acid and Platelet Rich Fibrin Injection Efficacy in Interdental Papilla Reconstruction
The goal of this clinical trial is to evaluate and compare the efficacy of injectable platelet rich fibrin (i-PRF) and hyaluronic acid (HA) in reconstruction of interdental papilla loss.
- Trial name
- NCT06314256
- Testing
- I-PRF Injection, Teosyal PureSense Global Action HA Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Intra-bony Pockets, Periodontitis
Biologicals in Management of Intra-Bony Defects
The aim is of this study is to evaluate and compare the effects (clinical and radiological) of different biomaterials on the repair of bone defects around the teeth.
- Trial name
- NCT07292870
- Testing
- Minimally invasive surgical treatment of the intra-bony defects, Use of the xenograft Bio-Oss® Collagen during the surgery, Use of enamel matrix derivative (Emdogain®)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Nasolabial Folds
Pilot Evaluation of Platelet Rich Fibrin Matrix (PRFM) for the Correction of Nasolabial Folds
Platelets are a component of blood, which contain factors which can enhance wound healing. This study proposes to evaluate the clinical response of laugh lines treated with a concentrated preparation of the subject's own…
- Trial name
- NCT00874094
- Testing
- Platelet rich fibrin matrix
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Wound Heal, Gingival Overgrowth
Different Platelet Concentrates After Gingivectomy and Gingivoplasty Evaluation of Its Effect on Early Wound Healing.
The aim of this study was to evaluate the effect of PRF, CGF and AFG application on early wound healing after gingivectomy and gingivoplasty operations.
- Conditions
- Wound Heal, Gingival Overgrowth, Gingival Enlargement, Platelet Rich Fibrin
- Trial name
- NCT04805463
- Testing
- Control group, PRF group, CGF group
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Inonu University
Alveolar Bone Loss, Tooth Extraction
Platelet Rich Fibrin (PRF) in Socket Preservation Technique
The loss of a tooth or change in its function is lead to a change in alveolar ridge's height and volume. Socket preservation (SP) is a procedure designed to prevent or limit alteration of the post-extraction bone ridge to achieve…
- Trial name
- NCT06173492
- Testing
- Dental extraction, Platelet Rich Fibrin
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Naples
Periodontitis Chronic Generalized Severe, Intrabony Periodontal Defect
Clinical and Radiograhic Evaluation of NIPSA With and Without Allograft Plus Platelet Rich Fibrin in the Treatment of Intraosseous Defects in Stage III Periodontitis Patients
Several minimal invasive techniques have been proposed since the last decade aiming to enhance and provide adequate environment for periodontal regeneration.
- Trial name
- NCT04444063
- Testing
- Non-Incised Papilla Surgical Approach
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession Types One(RT1), Gingival Crevicular Fluid
Comparison of Connective Tissue and PRF in Gingival Recession
Aim: In this study, it was aimed to comparatively investigate the clinical and biochemical effects of subepithelial connective tissue graft and coronally advanced flap (SCTG + CAF) or titanium-prepared platelet rich fibrin and…
- Trial name
- NCT07877064
- Testing
- Titanium-prepared Platelet-Rich Fibrin, SCTG + CAF
- Volunteers
- 22 people
- Sponsor
- Ataturk University
Soft Tissue Augmentation Around Dental Implants
Vertical Soft Tissue Augmentation With Tent Pole Technique and Its Influence on Marginal Bone Loss Around Dental Implants
This study aims to evaluate the effectiveness of the tent pole technique in vertical peri-implant soft tissue augmentation and to assess its impact on marginal bone loss.
- Trial name
- NCT07018531
- Testing
- VST augmentation with TPT, TPT-PRF, TPT-PBM
- Where
- 2 sites in Spain, Tunisia
- Volunteers
- 112 people
- Sponsor
- University of Santiago de Compostela
Gingival Recession
Comparison of Using Collagen Membrane and A-PRF Using VISTA Technique in Gingival Recession Treatment
To assess the efficacy of minimally invasive Vestibular Incision Subperiosteal Tunnel Access (VISTA) with collagen membrane and Advanced Platelet-rich Fibrin (A-PRF) in the treatment of multiple buccal gingival recession type…
- Trial name
- NCT06357351
- Testing
- vestibular incision sub periosteal tunnel access ( VISTA) technique.
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Intrabony Periodontal Defect
Regenerative Potential of Supercell Glue and Platelet Rich Fibrin Matrix
Utilizing the osteogenic properties of both platelet rich fibrin matrix and peripheral blood mesenchymal stem cells for periodontal regeneration would be novel and may be advantageous than using Platelet rich fibrin matrix alone.
- Trial name
- NCT03766139
- Testing
- SUPERCELL GLUE, PRFM ALONE
- Where
- India
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Anal Fistula, Rectal Fistula
Mechanical Bowel Preparation Prior To Sphincter-Sparing Surgery For Complex Anal Fistulae
The goal of this clinical trial is to learn whether bowel preparation with Plenvu before surgery improves healing of complex anal fistula in adults aged 18 to 64 years with a fistula of cryptoglandular origin or associated with…
- Conditions
- Anal Fistula, Rectal Fistula, Crohn Disease
- Trial name
- PLEN-SPARE (NCT07897539)
- Testing
- Mechanical bowel preparation
- Where
- Sweden
- Volunteers
- 116 people
- Sponsor
- Region Skane
Female Stress Urinary Incontinence
Comparison Between Two Techniques in Treatment of Female Stress Urinary Incontinence
compare the therapeutic effect of periurethral injection of autologous platelet-rich plasma (PRP) and injectable platelet rich fibrin (i-PRF) in treatment of female stress urinary incontinence and comparing the need for…
- Trial name
- NCT07366762
- Testing
- Platelet Rich Plasma, Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Peri-Implant Tissues
The Effect of Injectable Platelet-Rich Fibrin in Peri-implant Soft Tissue
An inadequate amount of peri-implant soft tissue results in more plaque accumulation around the implants, peri-implant mucositis, marginal bone loss, mucosal recession, and/or attachment loss.
- Trial name
- NCT06753396
- Testing
- Platelet rich fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kutahya Health Sciences University
Furcation Defects
Platelet Rich Fibrin+1% Alendronate in Treatment of Mandibular Degree II Furcation Defects
The present study was designed to evaluate the combined efficacy of PRF and 1% ALN in the treatment of mandibular degree II furcation defects when compared with PRF and open flap debridement (OFD) alone.
- Trial name
- NCT02609061
- Testing
- Open flap debridement (OFD), OFD with Platelet rich fibrin (PRF), OFD with Platelet rich fibrin (PRF)+1% Alendronate (Drug) in gel form
- Where
- India
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore