Clinical trials: Platelet Rich Fibrin
Patients with Posterior Maxillary Atrophy and Need for Sinus Lift Surgery to Allow Implant Placement
Efficacy of L-PRF Against Deproteinized Bovine Mineralized Bone (DBBM)
Objective: The main objective of this study is to evaluate whether the use of L-PRF combined with deproteinized bovine mineralized bone (DBBM; BioOss, Geistlich Pharma®) reduces healing time, through histomorphometric analysis…
- Trial name
- NCT06686836
- Testing
- Sinus lift augmentation with bone substitute (Bio-Oss), Open sinus lift surgery lift using Platelet- and leukocyte-rich fibrin (L-PRF) mixed with a bone substitute (Bio-Oss®(Geistlich AG, Wolhusen, Switzerland)) - L-PRF Block
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Osteoarthritis
Platelet Rich Plasma Combined With Platelet Rich Fibrin in Management of Temporomandibular Joint Osteoarthritis
Studying effectiveness of prp with prf comparing with prp or prf for mangement of tmj osteoarthritis as result in pain and mandibular movement in adult pt
- Trial name
- NCT06573502
- Testing
- Prp with prf or prp or prf
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Aliaa Babekir Ahmed Mohamed
Periodontal Health
Effects of Platelet-rich Fibrin and Vitamin Dꝫ Injections on the Periodontal Health
The study aims to evaluate the effect of using PRF and vitamin Dꝫ injections on periodontal health and parameters and compare them when used to facilitate orthodontic treatment.
- Trial name
- NCT06223477
- Testing
- Platelet-rich Fibrin, Vitamin D3
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Beni-Suef University
Necrotic Immature Permanent Teeth, Regenerative Endodontic Treatment
Application of Advanced Platelet-Rich Fibrin Plus (A-PRF+) in Revascularisation of Necrotic Immature Permanent Teeth
The goal of this clinical trial is to evaluate the effectiveness of an advanced platelet-rich fibrin plus (A-PRF+) revascularization procedure to promote healing and root development in necrotic immature permanent single-rooted…
- Conditions
- Necrotic Immature Permanent Teeth, Regenerative Endodontic Treatment, Pulp Regeneration, Root Maturation
- Trial name
- A-PRF+ (NCT07092488)
- Testing
- Advanced Platelet-Rich Fibrin Plus (A-PRF+) Revascularization Procedure
- Where
- Croatia
- Volunteers
- 28 people
- Sponsor
- University of Zagreb
Periodontitis, Periodontal Diseases
Clinical And Radiographic Evaluation Of Zinc Substituted Nanohyrdoxyappatite Bone Graft And Advanced Platelet Rich Fibrin Block In The Treatment Of Periodontal Intrabony Defects
Periodontal intrabony defects pose a significant challenge in clinical dentistry due to their complex anatomy and limited regenerative potential.
- Trial name
- R C S (NCT07313254)
- Testing
- OFD with zinc substituted nano HA combined with PRF block, OFD with zinc substituted nano HA, OFD with nano HA
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University
Acceleration of Tooth Movement
The Effect of Platelet-rich Fibrin and Vitamin Dꝫ Injections on Canine Retraction
the aim of this study is to assess and compare the effect of PRF and vitamin Dꝫ injection on the rate of canine retraction and to determine the bone thickness changes correlated with the two techniques.
- Trial name
- NCT06071455
- Testing
- Platelet-rich fibrin, Vitamin D3
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Beni-Suef University
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Healing Surgical Wounds, Pain
L-PRF vs PBM on Extraction Socket Healing
The aim of this study is to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and…
- Trial name
- NCT06328413
- Testing
- photobiomodulation, Leukocyte and Platelet Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Periodontitis
Injectable Platelet Rich Fibrin in Periodontal Treatment
The aim of this randomized controlled parallel clinical trial is to investigate the efficacy of injectable Platelet Rich Fibrin (iPRF) as an adjunctive to non-surgical periodontal therapy (STEP 1 \& 2 of periodontal treatment).
- Trial name
- I-PRF (NCT06814418)
- Testing
- Non-surgical periodontal treatment, Injectable Platelet Rich Fibrin (I-PRF)
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- Aristotle University Of Thessaloniki
Angle Class I
Evaluating the Effect of Injectable Platelet Rich Fibrin on Tooth Movement
Introduction: Prolonged orthodontic treatment can lead to challenges and unfavourable outcomes, including increased risk of caries, root resorption, as well as gingival and periodontal diseases.
- Trial name
- NCT06562452
- Testing
- Injectable platelet rich fbirin
- Where
- Vietnam
- Volunteers
- 31 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
L-PRF, Surgery
Root Coverage for Gingival Recessions: a Randomized Clinical Trial Using Coronally Advanced Tunnel Technique and Novomatrix®
A randomized clinical trial comparing the modified tunnel technique with the use of acellular xenogeneic matrix and connective tissue with the use leucocyte platlet rich fibrin (L-PRF)
- Trial name
- NCT06719648
- Testing
- Acellular dermal matrix + L-Prf, Connective Tissue graft + L-Prf
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Dental Implants, Tooth Extraction
Bovine-derived Xenograft With or Without L-PRF for Alveolar Ridge Preservation After Tooth Extraction: a Randomized Controlled Trial
The study is prospective randomized clinical trial that aims to evaluate the adjunctive use of L-PRF in promoting the desired vascularization and bone fill in small and large defects following tooth extraction and report on the…
- Conditions
- Dental Implants, Tooth Extraction, Bone Regeneration
- Trial name
- NCT06172114
- Testing
- Alveolar ridge preservation using sticky bone
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Gingival Recession, Localized
Extended Platelet- Rich Fibrin Membrane Combined With Vestibular Incision Subperiosteal Tunnel Access Technique to Treat Localized Gingival Recession
This study will be performed to clinically evaluate and compare the effectiveness of extended platelet-rich fibrin (e-PRF) membrane versus de-epithelized free gingival graft (DFGG) in combination with vestibular incision…
- Trial name
- alb prf REC (NCT07079293)
- Testing
- Preparation of Extended PRF, Harvesting of Free Gingival Graft and preparation of CTG, VISTA technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Sinus Lift Augmentation
Albumin-PRF in Sinus Lift With Implants: 2-Year Study
thirty-two implants will be inserted in patients seeking implantation of their lost posterior maxillary teeth (premolar and molars) with limited bone height below the floor of the maxillary sinus, secondary to sinus…
- Trial name
- NCT07367217
- Testing
- lateral sinus lift with using allograft and pericardium membrane, lateral sinus lift with using exteneded platelet rich fibrin
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Atrophic Maxilla, Ridge Preservation
Effect of L-PRF and A-PRF in Ridge Preservation
A split-mouth design study will be performed regarding the use of platelet concentrates on ridge preservation: L-PRF vs A-PRF vs control.
- Trial name
- NCT03268512
- Testing
- L-PRF, A-PRF
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sternal Wound Repair
Effects of Platelet Rich Fibrin (PRF) in Treatment of Non-healing Sternum Wound After Open-heart Surgery
Sternal wound and there complication such as infection, Bruising and scar formation are known as major complication cardiac surgery with a high mortality rate up to 50%.
- Trial name
- NCT03183973
- Testing
- PRF
- Where
- Iran
- Volunteers
- 45 people
- Sponsor
- SCARM Institute, Tabriz, Iran
Oral Sinus
Osseodensification Plus Platelet Rich Fibrin With Simultaneous Implant Installation in Closed Sinus Lift
12 patients with indirect sinus lift will be selected with RBH\>5mm , surgical procedure =osseodensification + Prf+ implant . 1.
- Trial name
- NCT05797675
- Testing
- prf + osseodensification
- Where
- Palestinian Territories
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Arab American University (Palestine)
Chronic Periodontitis
Advantages of Autologous Platelet-Rich Fibrin Membrane on Growth Factor Levels and Periodontal Healing
Platelet rich fibrin is a second generation platelet concentration which contains various growth factors. The aim of this study is to evaluate the clinical and biochemical efficacy of PRF in subjects of chronic periodontitis in…
- Trial name
- NCT02898675
- Testing
- Platelet rich fibrine, Open Flap Debridement
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Bisphosphonate-Associated Osteonecrosis of the Jaw
Prospective Randomized Study: Assessment of PRF Efficacy in Prevention of Jaw Osteonecrosis After Tooth Extraction
This prospective study will include patients taking or having taken bisphosphonates and needing dental extractions. The aim of this study is to validate the contribution of PRF (Platelet Rich Fibrin) in tooth extraction sites.
- Trial name
- PRF (NCT02198001)
- Testing
- tooth extraction with antibiotics (amoxicillin- clavulanate, clindamycine), atraumatic extraction
- Where
- 3 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Periodontoclasia, Gingiva; Injury
Use of Injectable-platelet-rich-fibrin (I-PRF) to Thicken Gingival Phenotype
The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival…
- Conditions
- Periodontoclasia, Gingiva; Injury, Condition, Blood Clot
- Trial name
- NCT03274674
- Testing
- I-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University