Clinical trials: Platelet Rich Fibrin
Injectable Platelet-Rich Fibrin, Minimally Invasive
Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Grade II Furcation Defects
This study aims to compare the clinical and radiographic effectiveness of injectable platelet-rich fibrin (i-PRF) combined with minimally invasive non-surgical therapy (MINST) versus MINST alone in the management of class II…
- Conditions
- Injectable Platelet-Rich Fibrin, Minimally Invasive, Non-Surgical Technique, Grade II Furcation Defects
- Trial name
- NCT07787949
- Testing
- Minimally invasive non-surgical technique (MINST), Minimally invasive non-surgical technique (MINST) + injectable platelet-rich fibrin (i-PRF) injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Regeneration, Periodontal Defects
REGENFAST vs L-PRF in Periodontal Regeneration
Introduction: Periodontal disease causes the progressive loss of supporting structures of the teeth, resulting in bone and soft tissue defects that compromise function and aesthetics.
- Conditions
- Regeneration, Periodontal Defects, Biomaterials
- Trial name
- NCT07430748
- Testing
- Periodontal Regenerative Surgery (REGENFAST®), Periodontal Regenerative Surgery (L-PRF)
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- University of Santiago de Compostela
TMJ Disc Disorder, TMJ Pain
I-PRF After Arthrocentesis Plus Botox Injection to Lateral Pterygoid Muscle in Treatment of Anterior Disc Displacement
Aim of Study : To evaluate the efficacy of TMJ arhtrocentesis followed by injection of liquid platelet rich fibrin (I-PRF ) in addition to intramuscular injection of lateral pterygoid muscle with botulinum toxin on clinical…
- Trial name
- NCT06207955
- Testing
- TMJ Arthrocentesis Followed By Injectable Platelet Rich Fibrin And Botulinum Toxin Type A, TMJ Arthrocentesis Followed By Injectable Platelet Rich Fibrin, TMJ Arthrocentesis
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Fayoum University
Alveolar Socket Preservation
Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).
The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used.
- Trial name
- Alb-PRF (NCT06757218)
- Testing
- empty socket, Autogenous Dentin Graft with Platelet Rich Fibrin, Autogenous Dentin Graft with Albumin Platelet Rich Fibrin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Gingival Recession
Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
This research will be conducted in an attempt to achieve complete root coverage with physiologic probing depth and a harmonious view with the adjacent tissues using Platelet rich fibrin in conjunction with Coronally advanced flap…
- Trial name
- NCT03199118
- Testing
- CAF +SCTG, platelet rich fibrin
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Trismus, Edema
Investigation of the Effects of CGF and A-PRF on Pain, Edema and Trismus After Impacted Lower Third Molar Surgery
The objective of this case-control intervention study is to explore the effectiveness of Concentrated Growth Factor (CGF) and Advanced Platelet Rich Fibrin (A-PRF) on Pain, Edema and Trismus After Impacted Lower Third Molar…
- Conditions
- Trismus, Edema, Pain, Post-Op Complication
- Trial name
- NCT03690167
- Testing
- Concentrated Growth Factor (CGF), Advanced Platelet Rich Fibrin (A-PRF), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Damla Torul
Sinus Lifting
Erythropoietin - Albumin Platelet-rich Fibrin in Transcrestal Sinus Lifting With Simultaneous Implant Placement
Background: Dental implant therapy in the posterior maxilla may be difficult owing to limited bone height after dental extraction with sinus pneumatization.
- Trial name
- NCT07150858
- Testing
- Erythropoietin and albumin PRF gel + implant placement, Albumin PRF gel +implant placement
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Localized Gingival Recession
Growth Factors in the Localized Gingival Recessions Treatment
The purpose of this study was to evaluate the clinical efficacy of concentrated-growth-factor (CGF) in combination with coronally-advanced-flap (CAF) compared with platelet-rich-fibrin (PRF)+CAF for the treatment of localized…
- Trial name
- NCT05188768
- Testing
- Concentrated Growth Factor Membrane, Platelet Rich Fibrin
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Gingival Recession, Localized
Extended Platelet- Rich Fibrin Membrane Combined With Vestibular Incision Subperiosteal Tunnel Access Technique to Treat Localized Gingival Recession
This study will be performed to clinically evaluate and compare the effectiveness of extended platelet-rich fibrin (e-PRF) membrane versus de-epithelized free gingival graft (DFGG) in combination with vestibular incision…
- Trial name
- alb prf REC (NCT07079293)
- Testing
- Preparation of Extended PRF, Harvesting of Free Gingival Graft and preparation of CTG, VISTA technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Liquid-PRF, A-PRF Plus
Effects of Recurrent Application of Liquid-PRF on Hard and Soft Tissues
Procedure: Tooth is extracted, then A-PRF+ is placed inside the socket. After that the ridge dimensions is asses clinically at the baseline) in addition to clinical assessment of the gingival biotype at the baseline.
- Trial name
- Liquid-PRF (NCT05492357)
- Testing
- Liquid platelet-rich fibrin, Advanced Platelet-rich fibrin plus
- Where
- Palestinian Territories
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cezar Edward Lahham
Patients with Posterior Maxillary Atrophy and Need for Sinus Lift Surgery to Allow Implant Placement
Efficacy of L-PRF Against Deproteinized Bovine Mineralized Bone (DBBM)
Objective: The main objective of this study is to evaluate whether the use of L-PRF combined with deproteinized bovine mineralized bone (DBBM; BioOss, Geistlich Pharma®) reduces healing time, through histomorphometric analysis…
- Trial name
- NCT06686836
- Testing
- Sinus lift augmentation with bone substitute (Bio-Oss), Open sinus lift surgery lift using Platelet- and leukocyte-rich fibrin (L-PRF) mixed with a bone substitute (Bio-Oss®(Geistlich AG, Wolhusen, Switzerland)) - L-PRF Block
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Head and Neck Disorder, Free Flap
Platelet-Rich Fibrin in the Healing of Regional and Free Flaps
Determine if the use of platelet-rich fibrin (PRF) versus historical treatment methods improves the post-operative management of healing complications from flap donor sites.
- Trial name
- NCT04023474
- Testing
- Platelet Rich Fibrin (PRF) Application
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Florida
Caries Active, Tooth Decay
Effects of Platelet and Leukocyte-rich Fibrin on Alveolar Ridge Maintenance Through Three-dimensional Analysis
Understanding, through accurate and reliable volumetric analysis, how the biomaterial (LPRF) and the thickness of the vestibular bone plate influence changes in bone volume after extraction, is essential for making clinical…
- Conditions
- Caries Active, Tooth Decay, Tooth Loss / Rehabilitation
- Trial name
- NCT07278180
- Testing
- Alveolar socket preservation with graft and flap surgery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Socket Preservation
Study on Platelet-Rich Fibrin for Preserving Jawbone After Tooth Extraction Using CBCT Imaging in Adults
The goal of this clinical trial is to learn if platelet-rich fibrin (PRF), a substance made from a person's own blood, helps preserve the bone in the jaw after tooth extraction in adults.
- Trial name
- NCT07022860
- Testing
- Platelet-rich fibrin (PRF)
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Zahedan University of Medical Sciences
Bone Loss
Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant
The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone
- Trial name
- NCT04298294
- Testing
- injectable platelet rich fibrin
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Photoaging
Platelet Rich Fibrin Versus Platelet Rich Plasma for Microneedling Treatment of Facial Photoaging
The present study was conducted for analyzing the efficacy and safety of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in photoaging therapy. Specific arms: 1.
- Trial name
- NCT06452667
- Testing
- platelet-rich fibin, platelet-rich palsma
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Gingival Recessions
Platelet-Rich Fibrin in the Treatment of Multiple Gingival Recessions
The main objective of this study was to evaluate the clinical effectiveness of platelet-rich fibrin membrane used in combination with a coronally advanced flap and to compare it with the use of a subepitelial connective tissue…
- Trial name
- NCT02335866
- Testing
- test groups, Control groups
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Sinus Lifting
Titanium Prepared Platelet-rich Fibrin in Bone Regeneration in Lateral Window Maxillary Sinus Augmentation
This trial aims to evaluate the effect of the sole use of T-PRF in bone formation process as applied in maxillary sinus floor elevation in comparison to traditional T-PRF/bone graft combination.
- Trial name
- NCT06135077
- Testing
- T-PRF alone, T-PRF/Xenograft
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Hams Hamed Abdelrahman
Periodontal Disease, Periodontal Bone Loss
Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials.
The present study is an effort to investigate the hypothesis that Platelet Rich Fibrin/Biphasic Calcium Phosphate may play a role in inhibiting osteoclasts differentiation and in bone loss.
- Conditions
- Periodontal Disease, Periodontal Bone Loss, Osteoclastic Bone Loss
- Trial name
- NCT03227367
- Testing
- other : PRF
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Periodontal Bone Loss
Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects
This study is meant to assess clinically the possible predictable clinical attachment gain regarding the use of vitamin C with platelet rich fibrin versus platelet rich fibrin alone in the treatment of periodontal intrabony…
- Trial name
- NCT03707483
- Testing
- combination of vitamin C and platelet rich fibrin
- Volunteers
- 20 people
- Sponsor
- Cairo University