Clinical trials: Platelet Rich Fibrin
Platelet-Rich Fibrin, Acceleration
The Effect of Multiple Injections of (PRF) on The Rate of Canine Retraction
this clinical trial aims to prove that multiple injections will produce a steady rate of acceleration of orthodontic tooth movement.
- Conditions
- Platelet-Rich Fibrin, Acceleration, Orthodontics
- Trial name
- NCT05766618
- Testing
- Injectable platelet rich fibrin (i-PRF): in acceleration of orthodontic tooth movement
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anastomotic Leak Rectum
Impact of Obsidian ® ASG on Anastomotic Healing
The use of regenerative medicine in colorectal surgery constitutes an entirely new therapeutic principle. The aim of this new therapeutic approach is to reduce the anastomotic leak rate and minimise morbidity and mortality.
- Trial name
- NCT04386148
- Testing
- Obsidian ASG®
- Where
- Austria
- Volunteers
- 270 people
- Sponsor
- Kepler University Hospital
Tooth Extraction
The Clinical and Biological Effects of Leucocyte and Platelet-rich Fibrin (L-PRF) on Post-extraction Sockets Healing
This study evaluates the clinical and biological effects of leucocyte and platelet-rich fibrin (L-PRF) on post-extraction sockets healing.
- Trial name
- NCT03985033
- Testing
- leucocyte and platelet-rich fibrin (L-PRF)
- Where
- Hong Kong
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Immediate Implant Soft Tissue Healing
ASSESSMENT OF SOFT TISSUE HEALING OVER IMMEDIATELY PLACED IMPLANT SEALED WITH PLATELETS RICH FIBRIN (PRF) VERSUS DIODE LASER
Aim of the current study was to assess the efficacy of PRF in comparison to diode laser to promote tissue healing and soft tissue quality after placement of immediate implants.
- Trial name
- NCT05517733
- Testing
- Platelet Rich Fibrin, Diode laser
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Nourhan M.Aly
Implantation Complication
L-PRF for Increasing Keratinised Mucosa Around Implants
The aim of this study was to evaluate the potential of L-PRF in increasing the width of the keratinsed mucosa around implants. Furthermore, it was assessed whether this surgery was associated with significantly less…
- Trial name
- NCT03190226
- Testing
- L-PRF membranes, Free Gingival Graft
- Volunteers
- 8 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Surgical Complication, Pain, Postoperative
Anti-inflammatory Effect of Platelet-Rıch Fıbrın
This study evaluated the anti-inflammatory effect of platelet-rich fibrin (PRF) applied to the extraction socket after impacted mandibular third molar surgery with subjective and objective parameters.
- Conditions
- Surgical Complication, Pain, Postoperative, Edema Face
- Trial name
- NCT05336578
- Testing
- Platelet rich fibrin application
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nilay Er
Gingival Recession, Gingival Recession, Localized
The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients with Gingival Recession.
Gingival recession is the term used to describe the apical positioning of the marginal gingiva from the enamel-cementum junction.
- Trial name
- NCT05591326
- Testing
- i-PRF application procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Alveolar Bone Loss, Tooth Loss
Changes of Soft and Hard Tissues After Alveolar Ridge Preservation: Freeze-dried Bone Allograft vs. L-PRF Clot
A Clinical Trial to study the effectiveness between two, tooth socket grafting materials namely, Freeze Dried Bone Allograft (human derived bone particles) and Leukocytic-Platelet Rich Fibrin (the patient's own centrifuged…
- Trial name
- NCT03331185
- Testing
- Freeze Dried Bone Allograft, L-PRF clot
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Bone Loss
Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes: An In Vitro Analysis
This study is seeking to evaluate that platelet-derived growth factor-BB (PDGF-BB) is a proven wound healing and osteogenic protein that plays a critical role in wound healing and previous research has demonstrated a non-linear…
- Trial name
- NCT04964466
- Testing
- Amount of PDGF-BB in PRF preparation vs. GEM21, Amount of PDGF-BB available in PRF + bone substitutes vs. rhPDGF-BB+ bone substitutes following preparation, Release kinetics of PDGF-BB in PRF + bone substitutes vs. rhPDGF-BB + bone substitutes
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Liquid-PRF, A-PRF Plus
Effects of Recurrent Application of Liquid-PRF on Hard and Soft Tissues
Procedure: Tooth is extracted, then A-PRF+ is placed inside the socket. After that the ridge dimensions is asses clinically at the baseline) in addition to clinical assessment of the gingival biotype at the baseline.
- Trial name
- Liquid-PRF (NCT05492357)
- Testing
- Liquid platelet-rich fibrin, Advanced Platelet-rich fibrin plus
- Where
- Palestinian Territories
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cezar Edward Lahham
Thin Gingiva
Comparative Evaluation of Microneedling and Injectable Platelet Rich Fibrin in Thin Periodontal Phenotype
Evaluation of microneedling vs injectable -platelet rich fibrin on gingival phenotype in thin periodontal phenotype.
- Trial name
- NCT05055765
- Testing
- Microneedling, injectable- platelet rich fibrin
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Photoaging
Platelet Rich Fibrin Versus Platelet Rich Plasma for Microneedling Treatment of Facial Photoaging
The present study was conducted for analyzing the efficacy and safety of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in photoaging therapy. Specific arms: 1.
- Trial name
- NCT06452667
- Testing
- platelet-rich fibin, platelet-rich palsma
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Three Wall Intrabony Defects in Chronic Periodontitis
Platelet Rich Fibrin Combined With Simvastatin for Treatment of Intrabony Defect in Chronic Periodontitis
The purpose of the present study was to investigate the efficacy of autologous Platelet rich fibrin (PRF) or PRF and Simvastatin (SMV) with open flap debridement (OFD) in the treatment of three wall intrabony defects in…
- Trial name
- NCT02120872
- Testing
- Platelet rich fibrin and simvastatin, Platelet rich fibrin, Open Flap Debridement alone
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Atrophy; Edentulous Ridge
Bone Changes in Atrophic Maxilla Treated by Split-crest Technique
The effect of adding Nanobone on horizontal bone gain in ridge splitting.
- Trial name
- NCT02836678
- Testing
- Ridge splitting, immediate implant, Nanobone with PRF., Ridge splitting, immediate implantand PRF.
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Extraction
Combination of Platelet-Rich Fibrin and Calcium Sulfate in Socket Augmentation
This study evaluated the effectiveness of socket grafting material, combination of plate-rich fibrin and calcium sulfate. 5 subjects were grafted with this material, 5 subjects were grafted with combination of plate-rich fibrin…
- Trial name
- NCT03851289
- Testing
- platelet-rich fibrin and calcium sulfate, platelet-rich fibrin and xenograft
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Mucosal Ulceration
Platelet-Rich Fibrin in Intraoral Soft Tissue Regeneration
Determine if the use of platelet rich fibrin (PRF) improves the rate and quality of healing for intraoral mucosal and epithelial soft tissue defects.
- Trial name
- NCT04022720
- Testing
- Platelet Rich Fibrin Application
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Rate of Tooth Movement in Orthodontic Patients
Evaluation of Effect of Platelet-Rich Fibrin on Orthodontic Tooth Movement: a Split Mouth Randomised Controlled Trial
it is a randomized control trial and aims at investigating the effects of PRF on rate of tooth movement and root length to be tested on larger sample size of pakistani population
- Trial name
- NCT06634017
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Recession, Gingival, Bone Loss in Jaw
L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant Placement
comparison between L-prf and connective tissue with dental implant
- Trial name
- NCT07102758
- Testing
- L-PRF with dental implant and customized healing abutment, Connective tissue with dental implant and customized healing abutment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Pain Syndrome
Pain After Removal of Mandibular Third Molars With or Without Advanced Platelet-rich Fibrin
Pain is the most common complication following surgical removal of an impacted mandibular third molar. Several risk factors may increase the intensity and duration of pain following removal of mandibular third molars.
- Trial name
- NCT06377839
- Testing
- Advanced platelet-rich fibrin in the ekstraction socket
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Tooth Extraction, Socket Preservation
Injectable Platelet-rich Fibrin and Advanced Platelet-rich Fibrin With Xenograft on the Socket Preservation of Mandibular Extracted Molars
Different materials and techniques are employed for socket preservation to reduce the alveolar bone resorption in both the horizontal and vertical dimensions as well as the soft tissue collapse after tooth extraction.
- Trial name
- NCT06936358
- Testing
- Control, A-PRF, I-PRF
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Hams Hamed Abdelrahman