Clinical trials: Platelet Rich Fibrin
Tooth Extraction
IMMEDIATE IMPLANT With Different Types of Membranes
forty patients will be selected from the outpatient's clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University for replacement of non-restorable tooth in posterior mandibular area.
- Trial name
- NCT06657651
- Testing
- immediate implant placement with dentin-derived membrane, immediate implant with extended platelet rich fibrin membrane
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Fibrin/Therapeutic Use, Blood Platelets
Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery
The purpose of this study is to evaluate the bone regeneration after impacted third molar surgery on split mouth design using platelet-rich fibrin.
- Conditions
- Fibrin/Therapeutic Use, Blood Platelets, Molar, Third, Bone Regeneration
- Trial name
- NCT02890680
- Testing
- Platelet-rich fibrin, Control group
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Maxillary Cyst
Using of Bone Marrow Stem Cell Concentrate with Platelet Rich Fibrin and Bone Graft in Bone Reconstruction of Upper Jaw Bony Cystic Defects, Comparing with Platelet Rich Fibrin with Bone Graft
Will the use of bone marrow stem cells with platelet rich fibrin enhance and accelerate the bone regeneration in the upper jaw cystic defects ?
- Trial name
- NCT06662604
- Testing
- Bone marrow stem cells concentrate , platelet rich fibrin , bone graft, platelet rich fibrin and bone graft
- Volunteers
- 22 people
- Sponsor
- Cairo University
Bone Loss, Alveolar
Effect of Collagen Versus PRF on BMA Osteogenic Potential
Utilization of collagen vs PRF membrane over the graft following sinus lift procedure and before suturing
- Trial name
- NCT05985317
- Testing
- Collagen membrane over BMAC/bovine graft in sinus lift, PRF membrane over BMAC/bovine graft in sinus lift
- Where
- Egypt
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Periodontal Pocket
Injectable PRF in Non-Surgical Periodontal Treatment
This study aims to evaluate the clinical and microbiological effects of using injectable Platelet-Rich Fibrin (i-PRF) as an adjunct to non-surgical periodontal therapy (scaling and root planing) in patients with periodontitis.
- Conditions
- Periodontitis, Periodontal Pocket, Alveolar Bone Loss
- Trial name
- IPRF-PERIO (NCT07375004)
- Testing
- Injectable Platelet-Rich Fibrin (i-PRF)., Scaling and Root Planing (SRP).
- Where
- Iraq
- Volunteers
- 18 people
- Sponsor
- Al-Mustansiriyah University
Low-output External Gastrointestinal Fistula
Glue Sealing for Patients With Low-Output ECFs
Adjuvant use of fibrin glue (FG) in the fistula tract has been shown to promote closure of low-output ECFs. The primary objectives of this study are to compare the clinical efficacy, safety of autologous platelet-rich fibrin glue…
- Trial name
- Glue-sealing (NCT01672593)
- Testing
- Endoscopy exploration and glue application, Anti-Bacterial Agents, Nutrition support
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jinling Hospital, China
Lateral Sinus Lifting
Lateral Sinus Augmentation Utilizing Bovine Bone Mixed with Platelet-rich Fibrin
Background: In sinus augmentation procedure, graft resorption remains a major dilemma of various graft materials. Objective: To estimate the graft volume changes following lateral sinus augmentation utilizing cone beam computed…
- Trial name
- NCT06810921
- Testing
- lateral sinus lift
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- University of Baghdad
Oral Surgery
The Effect of Platelet-rich Fibrin on Clinical and Patient-centered Outcomes of Third Molar Extractions
The fear of oral surgeries is mostly dedicated to pain and swelling in the following days. It is not surprising, that it is of high interest to do anything to reduce these consequences.
- Trial name
- PRF (NCT05089812)
- Testing
- Third-molar extraction using platelet-rich fibrin as a filling of the alveolus
- Where
- Austria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Platelet-Rich Fibrin (PRF), Impacted Mandibular Third Molar
Salivary α-Amylase as a Non-Invasive Biomarker of PRF-Enhanced Wound Healing After Third Molar Surgery
This randomized clinical study evaluated salivary α-amylase as a non-invasive biomarker of early wound healing after mandibular third molar surgery.
- Conditions
- Platelet-Rich Fibrin (PRF), Impacted Mandibular Third Molar, Postoperative Wound Healing, Salivary Alpha Amylase
- Trial name
- NCT07600619
- Testing
- PRF group
- Where
- Indonesia
- Volunteers
- 28 people
- Sponsor
- Hasanuddin University
Melasma, Facial Melasma
Injectable Platelet-Rich Fibrin Versus Intradermal Tranexamic Acid for Melasma
Melasma is a chronic acquired hyperpigmentation disorder that commonly affects the face and has a significant impact on quality of life.
- Trial name
- NCT07540702
- Testing
- Injectable Platelet-Rich Fibrin, Tranexamic acid 100 mg/mL (Kapron)
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Kasr El Aini Hospital
Maxillary Sinus
PRF Versus Advanced PRF in Sinus Augmentation
In the present study the main hypothesis , Advanced PRF will improve the bone quality and quantity in sinus augmentation
- Trial name
- NCT05134753
- Testing
- Advanced PRF, Control
- Volunteers
- 32 people
- Sponsor
- Cairo University
Wound Healing
Effect of Leucocyte- and Platelet-Rich Fibrin on Palatal Wound Healing After Free Gingival Graft Harvesting
Autogenous palatal free gingival graft harvesting presents challenges for patients due to the increased risk of postoperative morbidity related to a second intraoral surgical wound that heals with secondary intention.
- Trial name
- NCT06777069
- Testing
- Leucocyte and platelet rich fibrin membrane application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Istanbul Medipol University Hospital
Pulpitis - Irreversible
Effectiveness of Mineral Trioxide Aggregate and Platelet Rich Fibrin Along With Biodentine. .
The aim of this study was to clinically and radiographically evaluate the effectiveness of MTA, Biodentine, Platelet Rich Fibrin along with Mineral Trioxide Aggregate and Platelet Rich Fibrin along with Biodentine as pulpotomy…
- Trial name
- NCT04773886
- Testing
- Mineral trioxide aggregate, Biodentine, Platelet rich fibrin
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Recession
Surgical Management of Interdental Papilla Recession With Advanced Platelet Rich Fibrin or Connective Tissue Graft
deficient interdental papillae witt be surgically reconstructed. in one group, connective tissue graft (SCTG) will be used for papillae augmentation, while in the other group, advanced platelet rich fibrin (A-PRF).
- Trial name
- NCT05031169
- Testing
- interdental papilla surgical reconstructiion
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Chronic Non-healing Skin Ulcers
PRP Versus PRF Versus Conventional Treatment in Chronic Non-healing Skin Ulcers
To compare the therapeutic efficacy of PRP and PRF: two relatively newer modalities in the management of chronic non-healing ulcers versus conventional treatment.
- Trial name
- NCT06281483
- Testing
- platelet-rich plasma, platelet-rich fibrin, Surgical debridement, normal saline washing and dressing coverage
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kafrelsheikh University
Periodontitis, Intrabony Periodontal Defect
Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts
The use of injectable platelet-rich fibrin (i-PRF) in both surgical and non-surgical dental treatments has become increasingly widespread.
- Conditions
- Periodontitis, Intrabony Periodontal Defect, Periodontal Diseases, Periodontal Defect
- Trial name
- NCT07146776
- Testing
- open flap debridement with I-prf and xenogeneic graft, open flap debridement with saline and xenogenic graft
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Diabetic Foot
Platelet Rich Plasma VS Platelet Fibrin Plasma in Treatment of Diabetes Related Wound：a Randomized Controlled Trial
The goal of this randomized control trial is to compare the efficacy and safety of Platelet Rich Plasma VS Platelet Fibrin Plasma in patients with diabetes foot ulcer.
- Trial name
- NCT05979584
- Testing
- Platelet Fibrin Plasma, Platelet Rich Plasma
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Peking University Third Hospital
Periodontitis
Treatment of Periodontal Intrabony Defects Using Autologous Platelet Rich Fibrin vs Titanium Platelet Rich Fibrin
Background: To compare the effectiveness of open flap debridement (OFD) alone and OFD along with either Autologous Platelet Rich Fibrin (PRF) or Titanium Platelet Rich Fibrin (TPRF) in the treatment of intrabony defects (IBDs).
- Trial name
- NCT02512952
- Testing
- Open flap debridement (OFD), OFD with Platelet rich fibrin (PRF), OFD with Titanium Platelet rich fibrin (TPRF)
- Where
- 2 sites in India
- Volunteers
- 38 people
- Sponsor
- Government Dental College and Research Institute, Bangalore
Turbinate Surgery
Effects of Platelet-Rich Fibrin on Postoperative Outcomes Following Nasosinusal Surgery
tudy Design This was a prospective, randomized, double-blind, controlled clinical trial designed to evaluate the effects of platelet-rich fibrin (PRF) on postoperative healing following partial inferior turbinectomy.
- Trial name
- NCT07645053
- Testing
- Platelet-rich fibrin (PRF), Control
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Hospital Edmundo Vasconcelos
Rotator Cuff Tears of the Shoulder
Effect of Platelet-rich Fibrin on Rotator Cuff Repair
The objective of this study was to prospectively evaluate the influence of local application of Platelet Rich Fibrin (PRF) on the functional outcome and integrity of the arthroscopically repaired tendons in patients with massive…
- Trial name
- PRP-Fibrin (NCT01612845)
- Testing
- Arthroscopic repair without platelet rich fibrin, PRF (vivostat ®) administration after rotator cuff repair
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Hospital Universitario La Paz