Clinical trials: Platelet Rich Plasma
Neuroma, Phantom Limb Pain After Amputation
Ultrasound-Guided Platelet-Rich Plasma Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience chronic neuroma pain that may interfere with rehabilitation, prosthesis use, mobility, sleep, and quality of life.
- Conditions
- Neuroma, Phantom Limb Pain After Amputation, Stump Pain, Platelet-rich Plasma (PRP)
- Trial name
- PRP-NEUROMA (NCT07624890)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Local Anesthetic Injection
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Crohn Disease
Endoscopic Balloon Dilatation Combined With PRP Injection in Colonic Stenosis in Crohn's Disease
The aim was to investigate whether endoscopic balloon dilatation combined with PRP injection can help prevent or prolong restenosis in patients with Crohn's disease with colonic stenosis, and to explore the concentration of PRP.
- Trial name
- NCT06165289
- Testing
- PRP Injection
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Osteoarthritis, Knee
Intraosseous With Intra-articular Injection of Platelet Rich Plasma in Treatment of Knee Osteoarthritis
The aim of this study was to compare the efficacy of treatment in three groups of patients with knee osteoarthritis (OA) given a combination of intraosseous with intra-articular injection of platelet rich plasma (PRP)…
- Trial name
- NCT03329235
- Testing
- PRP, HA
- Volunteers
- 86 people
- Sponsor
- Cangzhou Central Hospital
Ocular Surface Disease, Dry Eye Syndromes
Platelet Rich Plasma Eye Drops for Treatment of Ocular Surface Disease
The purpose of this study is to evaluate prospectively the efficacy of topical administration of autologous platelet rich plasma as monotherapy for the treatment of symptoms and clinical signs in cases affected by moderate to…
- Trial name
- NCT04608084
- Testing
- Autologous platelet rich plasma eye drops
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Anterior Cruciate Ligament Injury
Arthroscopic Anterior Cruciate Ligament Reconstruction by Hamstring Graft With and Without Platelet-Rich Plasma
No local data exists regarding the outcomes of anterior cruciate ligament reconstruction by hamstring graft with and without platelet-rich plasma.
- Trial name
- NCT07269522
- Testing
- ACL reconstruction by hamstring graft with PRP, ACL reconstruction by hamstring graft
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Muhammad Aamir Latif
Osteoarthitis, Sacro Iliac Joint Pain
PRP Injection Into the Sacroiliac Joint After Ipsilateral THA: Effects on Early Recovery and Function (SIJ-THA Randomized Trial)
The study is an interventional, randomized, open-label (non-blinded), placebo-controlled trial. Preoperatively, patients scheduled for primary total hip arthroplasty (THA) will undergo a clinical examination in the Orthopaedic…
- Conditions
- Osteoarthitis, Sacro Iliac Joint Pain, Hip Arthroplasty, Total, Sacro-Iliac Spondylosis
- Trial name
- NCT07498660
- Testing
- PRP injection
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Anosmia, COVID-19
Effectiveness and Safety of Platelet Rich Plasma (PRP) on Persistent Olfactory Dysfunction Related to COVID-19
Olfactory dysfunction (OD) is a well know symptom of coronavirus disease 2019 (COVID-19), accounting for 48 to 85% of patients. In 1 to 10% of cases, patients develop a chronic olfactory dysfunction (COD,) lasting more than 6…
- Trial name
- NCT05226546
- Testing
- Platelet rich plasma (PRP), olfactory training
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Fistula in Ano
PRP Use in Treatment of Fistula Ano
In treatment of perianal fistula several methods are described. However, since the Hippocrates basics of surgical treatment has not changed very much.
- Trial name
- NCT04187651
- Testing
- platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uşak University
Periodontal Regeneration, Wound Healing
Effects of Standard PRP and Extracellular Vesicle-Enriched PRP on Human Gingival Fibroblasts
The goal of this study is to compare the biological effects of two blood-derived products, standard platelet-rich plasma (PRP) and extracellular vesicle-enriched PRP (EV-enriched PRP), on human gingival (gum) fibroblasts, the…
- Conditions
- Periodontal Regeneration, Wound Healing, Fibroblast
- Trial name
- NCT07855822
- Where
- Turkey (Türkiye)
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Inonu University
Vulvo Vaginal Atrophy
Regenerative Treatment of Female Genital Atrophy
Vulvovaginal health is a key aspect of active and healthy aging for all women. Hormonal deprivation that occurs during menopause significantly affects the anatomy and function of urogenital tissues, leading to their atrophy.
- Trial name
- RETREAT-FUGA (NCT07306611)
- Testing
- Mesotherapy with Autologous Platelet-Rich Plasma (PRP) to vulvovaginal area, Mesotherapy with saline solution, Platelet-Poor Plasma Gel
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- AndreiaAntunes
Osteoarthritis Knees Both
The Synergistic Effects of Intra-articular Hyaluronic Acid and Platelet-rich Plasma Injections on Knee Osteoarthritis
Although intra-articular knee injection with platelet-rich plasma (PRP) may have better outcomes than using hyaluronic acid (HA) for people with knee osteoarthritis (OA), it is expensive to use PRP.
- Trial name
- HAPRP (NCT04443166)
- Testing
- A platelet-rich plasma (PRP)+ hyaluronic acid (HA) program
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University WanFang Hospital
Platelet Rich Plasma
Platelet Rich Plasma and Diabetic Foot Ulcer
In chronic diabetic foot ulcer, if the conventional dressing fails, new therapeutic options such as recombinant human growth factors and bioengineered skin substitutes may be beneficial, but the cost is a limiting factor.
- Trial name
- NCT04750837
- Testing
- debridement of the wound, platelet rich plasma, conventional dressing
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Androgenetic Alopecia (AGA)
Clinical Study of PRP in the Treatment of Androgenetic Alopecia
A study on the therapeutic effect of platelet-rich plasma in the treatment of androgenetic alopecia
- Trial name
- NCT07551271
- Testing
- PRP
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Anterior Cruciate Ligament Tear, Posterior Cruciate Ligament Tear
Effect of Physical Therapy and/or Platelet Rich Plasma Injection in People With Knee Cruciate Ligament Injuries
Background: The anterior cruciate ligament(ACL) , one of the major ligaments in the knee joint which connects the posterior aspect of the lateral femoral condyle to the anterior intercondylar area of the tibia.
- Trial name
- NCT06233305
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Infertile Patients
the Effect of Hyaluronic Acid Intrauterine Wash on Endometrial Receptivity and Pregnancy Outcome
Hyaluronic acid intrauterine wash is done for infertile females undergoing intracytoplasmic sperm injection on the day of oocyte retrieval.
- Trial name
- NCT06937645
- Testing
- Hyaluronic Acid (HA), platlet rich plasma (PRP)
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- Al-Nahrain University
No Disease or Condition is Being Studied
Evaluation of the Performance and Safety of VACUSERA® PRP Tubes in the Preparation of Autologous Platelet-Rich Plasma
Study Design After the eligibility assessment during screening and obtaining a written informed consent form, the volunteers' demographic information and medical history will be recorded.
- Trial name
- PRP (NCT07041918)
- Testing
- The study is entirely designed to analyze product performance (analyze only results from whole blood and derived from the PRP tubes), and no interventions will be performed.
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Disera Tıbbi Cihazlar Lojistik Sanayi ve Ticaret A.Ş
Bony Defect
Scheduled Autologous PRP Guided Injection in the Maxillary Bony Defects
Scheduled autologous platelet-rich plasma guided injection is done in critical-sized maxillary bony defects after surgical excision of non- malignant lesions.
- Trial name
- NCT07108933
- Testing
- Autologous platelet-rich plasma
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Horus University
Epicondylitis, Lateral
Injection in the Treatment of Lateral Epicondylitis. Randomized Controlled Trial
The aim of the study is to compare the effectiveness of injection techniques in the treatment of elbow lateral epicondylitis. The functional and pain levels of the patients will be evaluated with scores such as DASH, VAS, PRTEE.
- Trial name
- NCT04875338
- Testing
- plate-rich plasma, saline (0.9 NACI), betametazon
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Infertility of Uterine Origin
Platelet Rich Plasma for Insufficient Endometrium
To determine the effectiveness of an intrauterine PRP infusion on endometrial thickness and in vitro fertilization (IVF) outcomes in a population of infertile women with a history of unresponsive thin endometrium.
- Trial name
- PIER (NCT05538338)
- Testing
- Platelet Rich Plasma Intrauterine infusion, Normal saline Intrauterine infusion
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Urinary Incontinence,Stress, Urinary Incontinence
Platelet-Rich Plasma for Stress Urinary Incontinence
The aim of this randomized controlled trial study is to evaluate the efficacy and safety of platelet-rich plasma (PRP) in the treatment of female stress urinary incontinence (SUI), compared to placebo.
- Trial name
- NCT05390970
- Testing
- Platelet-rich plasma injection
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Annah J. Vollstedt