Clinical trials: Platelet-Rich Plasma
Breast Cancer, Lipofilling
Evaluation of the Efficacy and Safety of Using Platelet-rich Fibrin (PRF)-Based Lipobolus for the Immediate Reconstruction of Defects After Breast-conserving Resection for Breast Cancer (Minimally Invasive Primary Immediate Grafting)
The goal of this clinical trial is to learn if a special type of fat graft, made by mixing a person's own fat with platelet-rich fibrin (PRF), works to fix breast shape defects after cancer surgery.
- Conditions
- Breast Cancer, Lipofilling, Fat Graft, Platelet Rich Plasma
- Trial name
- MINIPIG (NCT07658170)
- Testing
- Lipobolus (Autologous Fat + Platelet-Rich Fibrin+Calcium chloride)
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- The Leningrad Regional Clinical Hospital
Knee OA
a Single HYAJOINT Plus Combined With a Single PPR Versus a Single PRP for Knee OA
Intraarticular hyaluronan or platelet-rich plasma (PRP) is each effective in the treatment for knee osteoarthritis (OA). The efficacy of combined hyaluronan with PRP for knee OA remained unclear.
- Trial name
- NCT04315103
- Testing
- a single intraarticular injection of HYAJOINT Plus (3 ml) followed by 3 ml PRP
- Where
- 2 sites in Taiwan
- Volunteers
- 85 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Persistent Corneal Epithelial Defects, Dry Eye
Platelet Rich Plasma in Corneal Surface Diseases
The Aim of the study is to evaluate the efficacy of platelet rich plasma eye drops in the management of different corneal surface disorders.
- Trial name
- NCT05320172
- Testing
- Autologous platelet rich plasma eye drops
- Volunteers
- 70 people
- Sponsor
- Assiut University
Dry Eye, Sjogren Syndrome
Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye
Dry eye is a chronic condition that decreases function and affect visual function with severe discapacity until now treatments are based in artificial eye drops.
- Trial name
- NCT02257957
- Testing
- PRP injection, Standard care Hyaluronic acid eye drops
- Volunteers
- 30 people
- Sponsor
- Universidad Nacional de Colombia
Osteo Arthritis Knee, Pain, Chronic
Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis
Osteoarthritis (OA) affects aged above 45 years. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities.
- Trial name
- NCT03886142
- Testing
- radiofrequency, platelet rich plasma injection
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Knee Osteoarthritis
Clinical Investigation to Compare the Safety and Efficacy of Cellular Matrix to Those of Ostenil® Plus and to Those of PRP Only
Platelet-rich plasma (PRP) is an autologous product prepared from the patient's own blood, representing a powerful source of platelet-derived growth factors, particularly useful in the field of regenerative medicine.
- Trial name
- NCT02964143
- Testing
- Cellular Matrix / A-CP HA, Ostenil® Plus, RegenKit-BCT-1
- Volunteers
- 306 people
- Sponsor
- Regen Lab SA
Erectile Dysfunction
Evaluating the Efficacy of Platelet-Rich-Plasma (PRP) for Erectile Dysfunction
There is great interest in restorative therapies (platelet-rich plasma (PRP) injections, shockwave therapy and stem cell therapy) for ED given their non-invasive nature.
- Trial name
- NCT06264635
- Testing
- Platelet-Rich-Plasma, Saline
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Carpal Tunnel Syndrome
Platelet Rich Plasma and Perineural Injection Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02696161
- Testing
- platelet rich plasma, 5% dextrose
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Adhesive Capsulitis of Shoulder, Adhesive Capsulitis
Efficacy of Platelet Rich Plasma Injections in Patients With Adhesive Capsulitis of the Shoulder
This study was done to investigate whether platelet rich plasma(PRP) injections are effective in the management of adhesive capsulitis of the shoulder(AC).Patients were randomized to 2 groups, and one group took PRP injections…
- Conditions
- Adhesive Capsulitis of Shoulder, Adhesive Capsulitis, Frozen Shoulder
- Trial name
- NCT03951896
- Testing
- PRP, Saline injection
- Volunteers
- 32 people
- Sponsor
- Ege University
Rotator Cuff Injuries
The Effect of Platelet Rich Plasma on Partial Thickness Rotator Cuff Tears: A Randomized Controlled Trial
Randomized controlled trial examining platelet rich plasma versus corticosteroid injection in partial thickness rotator cuff tears or tendinopathy.
- Trial name
- PRP (NCT04743986)
- Testing
- Platelet Rich Plasma (PRP), Corticosteroid (CS)
- Volunteers
- 104 people
- Sponsor
- University of Calgary
Erectile Dysfunction
The Role of Platelet Rich Plasma for Erectile Dysfunction
Purpose of Study: This randomized controlled trial investigates the role that platelet rich plasma injections into the penis may play to improve erectile function in men with erectile dysfunction.
- Trial name
- NCT04357353
- Testing
- Platelet rich plasma
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Osteoarthritis
The Effect of Platelet-rich Plasma in Patients With Osteoarthritis of the Knee
Osteoarthritis is the most common type of arthritis. The prevalence of osteoarthritis of the knee has significantly elevated in the elderly population and youth due to age and sport activities respectively.
- Trial name
- NCT01926327
- Testing
- PRP injection
- Where
- Iran
- Volunteers
- 150 people
- Sponsor
- Royan Institute
Presbylarynx, Atrophy; Larynx
Serial Platelet-Rich Plasma Injections for Vocal Fold Atrophy, Scar, and/or Sulcus Vocalis
This study will investigate the safety and efficacy of four serial monthly vocal fold injections of platelet-rich plasma to treat dysphonia secondary to vocal fold atrophy, scar, and/or sulcus vocalis with glottal insufficiency
- Conditions
- Presbylarynx, Atrophy; Larynx, Dysphonia, Vocal Cord Atrophy
- Trial name
- NCT03749863
- Testing
- Serial PRP injections
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Greater Trochanteric Pain Syndrome
Efficacy of Platelet Rich Plasma vs. Corticosteroid Injections for Treating Greater Trochanteric Pain Syndrome
The object of this study is to compare the effect of PRP versus Corticosteroid injection on pain in patients with Greater Trochanteric Pain Syndrome up to 12 months after treatment.
- Trial name
- NCT02031367
- Testing
- Triamcinolone Acetonide, Platelet Rich Plasma
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- C.R.Darnall Army Medical Center
Androgenetic Alopecia
Adipose Derived Stem Cells Versus Platelet Rich Plasma on Follicular Unit Extraction
Androgenetic alopecia is the most common type of alopecia in both men and women. About 80 % of Caucasian men and 40-50 % of Caucasian women are affected by androgenetic alopecia.
- Trial name
- NCT03388840
- Testing
- Adipose derived stem cells suspention, Platelet rich plasma
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Stress Urinary Incontinence (SUI)
The Effect of Periurethral Injection of Platelet Rich Plasma Versus Mid-urethral Sling in Treatment of Stress Urinary Incontinence
this study used to compare efficacy between platelet rich plasma periurethral injection versus mid urethral sling ( trans obturator tape ) in treatment of stress urinary incontinence
- Trial name
- NCT07550426
- Testing
- Platelet Rich Plasma, Mid urethral sling ( trans obturator tape)
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Painful Bladder Syndrome (PBS), Interstitial Cystitis
Submucosal Intravesical Injection of Platelet-rich Plasma in the Treatment of Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is characterized by a constellation of bladder symptoms, including urinary frequency, urgency, nocturia, and pelvic pain.
- Trial name
- PRP (NCT06209008)
- Testing
- Intravesical injection of Platlet Rich Plasma (PRP)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Temporomandibular Joint Disorders
Temporomandibular Bioviscosuplementation (Platelet-Rich Plasma Combined With Hyaluronic Acid) After Double-Puncture Arthrocentesis: a Randomized Controlled Trial
Intra-articular injections of hyaluronic acid (HA) or platelet-rich plasma (PRP) have been used with temporomandibular joint (TMJ) arthrocentesis to improve lubricative properties and influence regenerative processes.
- Trial name
- NCT06457698
- Testing
- Double-puncture TMJ arthrocentesis under local anaesthesia
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Instituto Portugues da Face
Rotator Cuff Injuries, Shoulder Joint
Platelet-Rich Plasma Versus Home-Based Exercise for Partial-Thickness Supraspinatus Tears
This study evaluates the clinical effectiveness of platelet-rich plasma (PRP) injections compared with a home-based exercise program in patients with partial-thickness tears of the supraspinatus tendon.
- Conditions
- Rotator Cuff Injuries, Shoulder Joint, Shoulder Pain
- Trial name
- NCT07246434
- Testing
- Platelet-Rich Plasma (PRP), Home Exercise Program
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Extremadura
the Efficacy of Ultrasound Guided Sacroiliac Injection of Ozone, Platelet Rich Plasma (PRP) or Steroid for Treatment of Sacroiliitis
Comparison Between Ultrasound Guided Ozone, Platelet-Rich Plasma or Steroid Injection in the Treatment of Sacroiliitis; a Randomized Double Blinded Controlled Study
Comparison between ultrasound guided Ozone, platelet-rich plasma or steroid injection in the treatment of sacroiliitis; a Randomized Double Blinded Controlled Study
- Trial name
- NCT05914350
- Testing
- ultrasound guided Ozone, platelet-rich plasma or steroid injection in the treatment of sacroiliitis, methylprednisolone acetate and lidocaine, PRP and lidocaine
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Tanta University