Clinical trials: Platelet-rich Plasma (PRP)
Osteoarthritis
Precision Assessment of Platelet Rich Plasma for Joint Preservation
Knee Osteoarthritis (OA) is a leading cause of premature disability in Veterans who develop knee OA at higher rates and younger ages than the population in general.
- Trial name
- NCT03460236
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Atrophic Rhinitis
A Clinical Study to Evaluate the Safety and Efficacy of Platelet Rich Plasma Injection for Atrophic Rhinitis
The goal of the suggested research is to develop a treatment option using platelet rich plasma injection for regeneration of atropic nasal mucosa.
- Trial name
- ARPRP (NCT03112330)
- Testing
- Plasma rich platelet injection, Saline nasal spray
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul St. Mary's Hospital
Osteoarthritis
Leukocyte-rich PRP vs Leukocyte-poor PRP for the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial
Platelet-rich Plasma (PRP) is the most exploited biologic agents currently used for the treatment of osteoarthritis (OA) of different joints, in particular knee OA.
- Trial name
- PRP014 (NCT02923700)
- Testing
- Leukocyte-rich PRP intra-articular injections, Leukocyte-poor PRP intra-articular injections
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- Istituto Ortopedico Rizzoli
Orbital Atrophy
Botulinum-assisted Orbital Fat Augmentation With PRP (Platelet-rich-plasma)
immobilization of yoked extra-ocular muscles in the anophthalmic orbit, in conjunction with platelet-rich-plasma, will improve integration of viable adipocytes injected into orbital fat
- Trial name
- NCT02244671
- Testing
- fat, PRP, botulinum toxin, botulinum toxin, PRP
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Fox, Donald Munro, M.D., P.C.
Infertility,Female
G-CSF and PRP in Patients With Recurrent Implantation Failure
The aim of this randomized controlled trial is to determine whether granulocyte colony-stimulating factor and platelet-rich plasma can be used to enhance the IVF-ET outcomes in patients with recurrent implantation failure
- Trial name
- NCT04411212
- Testing
- Granulocyte colony-stimulating factor and platelet-rich plasma group, Control group
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Riyadh Fertility and Reproductive Health center
Melasma
Efficacy of Intralesional PRP +/- Topical Silymarin in the Treatment of Melasma
Melasma is an acquired disorder of melanogenesis leading to hyperpigmentation and manifested by symmetrical brown to gray-black macules and patches with serrated irregular edges .
- Trial name
- NCT05626881
- Testing
- PRP, sylimarin cream
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Recurrent Implantation Faliure, Infertility
Subendometrial Injection Versus Intrauterine Infusion of Platelet Rich Plasma for Women With Recurrent Implantation Failure
Aim of this study is to compare the effectiveness of subendometrial PRP injection \& intrauterine PRP infusion in women with recurrent implantation failure in comparison with a control group .
- Trial name
- NCT07306871
- Testing
- Platelet rich plasma, No intervention /standard care
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Peyronies Disease
Platelet-Rich Plasma for Peyronie's Disease
The purpose of this clinical trial is to evaluate the effects of Platelet-Rich Plasma (PRP) intralesional injections in men affected by Peyronie's disease (PD) in the fibrotic phase.
- Trial name
- NCT07117955
- Testing
- Autologous Platelet Rich Plasma, Saline solution
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Herlev Hospital
Oral Pemphigus Vulgaris
Comparison Between Injections of Steroids and Autologous Platelet Rich Plasma in the Oral Erosions of Pemphigus Vulgaris
Comparing the effect of injecting autologous platelet rich plasma and triamcinolone acetonide in the erosions of buccal mucosa of pemphigus vulgaris patients.
- Trial name
- NCT02828163
- Testing
- Autologous Platelet rich plasma, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Cairo University
Patients with Jaw Muscles Myofascial Pain
A Comparative Study on the Impact of Trigger Points Injection of Platelet Rich Plasma Versus Botulinum Toxin on the Relief of Jaw Muscles Myofascial Pain
This study aims at comparing the effect of trigger points injection of platelet rich plasma and botulinum toxin a on the relief of jaw muscles Myofascial pain .
- Trial name
- NCT06814535
- Testing
- Botulinum Toxin A / Botulinum Toxin A, Platelet rich plasma
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lumbar Spondylosis
Study Evaluating the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain
This study is being done to assess the safety of using the Angel Concentrated Platelet Rich Plasma System to process Platelet Rich Plasma (PRP) to treat arthritis of the low back (lumbar spondylosis).
- Trial name
- NCT05250947
- Testing
- Angel® Concentrated Platelet Rich Plasma System, Platelet Rich Plasma
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Matthew Pingree
Peripheral Nerve Injury Upper Limb
Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study
The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults.
- Trial name
- NCT06638008
- Testing
- perineural injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Peyronies Disease
Treatment of Peyronie's Disease With Platelet-Rich Plasma
The purpose of this pilot study is to optimize a planned randomized, double-blind, placebo-controlled clinical trial evaluating the effects of Platelet-Rich Plasma (PRP) intralesional injections in men affected by Peyronie's…
- Trial name
- NCT06789510
- Testing
- Autologous Platelet Rich Plasma, Saline solution
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Herlev Hospital
Cesarean Section Wound, Platelet-rich Plasma (PRP)
Efficacy of Platelet-rich Plasma in Improving Postoperative Scarring After Cesarean Delivery
Cesarean section often leads to postoperative scarring, which can impact both physical and psychological well-being. Platelet-rich plasma (PRP), rich in growth factors, is used in regenerative medicine to promote healing and…
- Conditions
- Cesarean Section Wound, Platelet-rich Plasma (PRP), Regenerative Medicine
- Trial name
- PRP06081992 (NCT06978010)
- Testing
- Platelet-Rich Plasma (PRP) intraoperatively
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Rotator Cuff Tendinosis, Supraspinatus Strain
The Effects of Platelet-Rich Plasma Versus Prolotherapy On Rotator Cuff Tendinopathy: A Randomized Controlled Trial.
Rotator cuff tendinopathy is the common cause of shoulder pain in the working-age group and the elderly (1). The condition reported takes an average of 10 months or longer to recover.
- Conditions
- Rotator Cuff Tendinosis, Supraspinatus Strain, PRP
- Trial name
- NCT04640662
- Testing
- Platelet-Rich Plasma, Prolotherapy
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Osteoarthritis Thumb
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
- Trial name
- NCT06193499
- Testing
- Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Osteoarthritis, Knee, Fractures, Ununited
Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal System
Brief Summary This clinical study investigates the safety and effectiveness of combining advanced regenerative therapies with personalized surgical technology for patients with delayed fracture healing (non-unions), knee…
- Conditions
- Osteoarthritis, Knee, Fractures, Ununited, Arthroplasty, Replacement, Knee
- Trial name
- MTDMS (NCT07628010)
- Testing
- Autologous Mesenchymal Stromal Cells Combined with Platelet-Rich Plasma, Patient-Specific 3D-Printed Surgical Instruments
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zaporizhzhiya State Medical University
Supraspinatus Tear
Platelet Rich Plasma and Supraspinatus Tear
Rheumatology and Rehabilitation Department, Mansoura University Hospital. Forty patients with chronic partial supraspinatus tears will be included in the study.
- Trial name
- NCT03942679
- Testing
- PRP, physiotherapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Rotator Cuff Tears
Effect of the Muscle Strength and Range of Motion Training for Post-platelet Rich Plasma Injection in People With Rotator Cuff Partial Tear
Background: Although it is known that Platelet-Rich Plasma injections have a remarkable pain relief effect for patients with partial tears of the rotator cuff in the shoulder joint, many patients still experience limited muscle…
- Trial name
- NCT06192459
- Testing
- Modality physical therapy, Combined therapy:
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Diabetic Peripheral Neuropathy
Efficacy of Platelet Rich Plasma Injection in Diabetic Neuropathy
To evaluate the clinical efficacy and safety of peri-neural platelet rich plasma (PRP) injection in the treatment of diabetic peripheral neuropathy compared to traditional medical treatment.
- Trial name
- NCT03250403
- Testing
- PRP injection, traditional medical treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University