Clinical trials: Platelet-rich Plasma (PRP)
Osteoarthritis, Knee
Steroids, Hyaluronic Acid or Platelet Rich Plasma Versus Placebo for the Knee Osteoarthritis
This study investigates clinical outcome and imaging outcome parameters after intraarticular injection of steroids, platelet-rich-plasma (prp), hyaluronic acid or placebo in patients with early osteoarthritis of the knee joint.
- Trial name
- KIT (NCT02776514)
- Testing
- Triamcort, Platelet-rich-plasma, Suplasyn1
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Balgrist University Hospital
Olfactory Disorder, Olfaction Disorders
Intranasal Injection of PRP Versus Saline for Treatment of Olfactory Dysfunction
This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PrP) in the treatment of olfactory dysfunction.
- Conditions
- Olfactory Disorder, Olfaction Disorders, Olfactory Nerve Injuries, Olfactory Nerve Disorder
- Trial name
- NCT04406584
- Testing
- Injection into olfactory cleft
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Platelet-Rich Plasma (PRP), Knee Osteoarthritis (OA)
Validation of a Low-cost Platelet-Rich Plasma (PRP)
Knee osteoarthritis is an extremely common and debilitating condition, more common in women, with an estimated global prevalence of 16%, and as high as 50% by the age of 80.
- Trial name
- PRP (NCT06184048)
- Testing
- Intra-Articular knee injection of LC-PRP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Anosmia
Efficacy of Platelet-rich Plasma in Management of Anosmia
Olfactory dysfunction is a prevalent disorder that affects up to 20% of the general population and has significant effects on a person's quality of life as well as increased morbidity and mortality (Croy I et al., 2014;Nordin S…
- Trial name
- NCT06930248
- Testing
- Platelet rich plasma injection
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Ulcer
PRP ULCERAS: Clinical Trial Phase III
INTRODUCTION: Vascular ulcers are an important pathology in the daily medical practice in all the assistance levels, and they have big repercussion referring to individual, social and labour levels, supposing a big consumption of…
- Trial name
- PRPULCERAS (NCT02213952)
- Testing
- Platelet-Rich Plasma, Usual treatment
- Where
- 2 sites in Spain
- Sponsor
- Basque Health Service
Genitourinary Syndrome of Menopause (GSM)
CO₂ Laser With or Without Platelet-Rich Plasma for Genitourinary Syndrome of Menopause
This study evaluated whether adding platelet-rich plasma (PRP) to fractional CO₂ laser treatment provides additional benefit for postmenopausal women with genitourinary syndrome of menopause (GSM).
- Trial name
- NCT07863739
- Testing
- Fractional CO₂ Laser, Autologous Platelet-Rich Plasma (PRP)
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- National and Kapodistrian University of Athens
Knee Osteoarthritis
High Frequency Intensive Autologous PRP Injection and Genicular Nerve Blocks in Treating Knee Osteoarthritis
Osteoarthritis (OA) of the knees is the most common degenerative disorder seen in a rehabilitation outpatient clinic. It is characterized by structural changes in the articular cartilage and the surrounding tissues.
- Trial name
- NCT04088045
- Testing
- Autologous platelet rich plasma and 5% dextrose solution injections.
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Knee Osteoarthritis
Effect Of Plasma Rich In Growth Factors In Knee Osteoarthritis
HYPOTHESIS: The application of plasma rich in growth factors (PRGF) will improve the quality of life and functional capacity of patients diagnosed with knee osteoarthritis, providing better functional results than conventional…
- Trial name
- NCT02039531
- Testing
- Plasma rich in growth factors, Hyaluronic Acid
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
Platelet Rich Plasma
Platelet Rich Plasma and Diabetic Foot Ulcer
In chronic diabetic foot ulcer, if the conventional dressing fails, new therapeutic options such as recombinant human growth factors and bioengineered skin substitutes may be beneficial, but the cost is a limiting factor.
- Trial name
- NCT04750837
- Testing
- debridement of the wound, platelet rich plasma, conventional dressing
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Platelet Rich Plasma Injection, Ultrasonography
The Effects of Intra-articular and Peri-articular Platelet-rich Plasma (PRP) Injections ın Chronic Knee Osteoarthritis
The primary objective of this study is to evaluate and compare the effectiveness of ultrasound-guided combined intra-articular and peri-articular platelet-rich plasma (PRP) injections with intra-articular PRP injections alone in…
- Conditions
- Platelet Rich Plasma Injection, Ultrasonography, Gonarthrosis
- Trial name
- NCT07339137
- Testing
- Conservative Therapy, Intra-Articular PRP, Peri-Articular PRP
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Stricture Urethra
The Effect of Platelet Rich Plasma Injection on Post Internal Urethrotomy Stricture Recurrence
The effect of platelet rich plasma injection on post internal urethrotomy stricture recurrence
- Trial name
- prp vs VIU (NCT07837167)
- Testing
- PRP injection, VIU
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Benha University
Intrauterine Adhesion
PRP Prevents Recurrence of Intrauterine Adhesions
Effect of platelet-rich plasma (PRP) on uterine scar fibrosis, endometrial receptivity and pregnancy outcome in patients with severe intrauterine adhesions
- Trial name
- RPR-IUAs (NCT03629132)
- Testing
- Platelet-rich plasma, gel
- Volunteers
- 60 people
- Sponsor
- Yanhong Deng
Supraspinatus Tear
Platelet Rich Plasma and Supraspinatus Tear
Rheumatology and Rehabilitation Department, Mansoura University Hospital. Forty patients with chronic partial supraspinatus tears will be included in the study.
- Trial name
- NCT03942679
- Testing
- PRP, physiotherapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Temporomandibular Joint Disorders
Effects of Platelet-rich Plasma Prolotherapy of Temporomandibular Joint Subluxation
The aim of this study is to clinically assess the efficacy of PRP prolotherapy for treatment of TMJ subluxation
- Trial name
- NCT03655275
- Testing
- PRP prolotherapy, Saline prolotherapy
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Abdelrahman Soliman Alateyh
Impacted Third Molar Tooth
Evalution of the Effects of PRP and LLLT on Postoperative Complications and Wound Healing After Impacted Third Molar
The aim of the study was to compare the possible effects of platelet-rich plasma (PRP) and low-level laser (BIOLASE) on postoperative complications after extraction of impacted mandibular wisdom teeth.
- Trial name
- NCT06836570
- Testing
- Platalet Rich Plasma, Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Ulcer Foot, Chronic Skin Ulcer
Platelet Rich Plasma (PRP) Bio Stimulant Gel Dressing in Treating Chronic Non Healing Leg and Foot Ulcers: Cost and Effectiveness
Background Chronic non-healing ulcer is a common problem met in clinical practice and represents a burden to the patients. Chronic ulcer lacks growth factors (GFs) to promote the healing process and is frequently followed by…
- Conditions
- Ulcer Foot, Chronic Skin Ulcer, Non-Healing Ulcer of Skin
- Trial name
- NCT04065594
- Testing
- PRP dressing, conventional ordinary dressing
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Herniated Disc
Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain
The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications.
- Trial name
- NCT07036445
- Testing
- Epidural Steroid Injection, Epidural platelet-rich plasma injection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Poor Ovarian Reserve
Autologous Intraovarian Platelet Rich Plasma Treatment in Women With Poor Ovarian Response
Reproductive age women diagnosed with poor ovarian response (POR) based on Bologna criteria with a history of at least two prior failed ICSI cycle will be recruited for the study.
- Trial name
- NCT04797377
- Testing
- Autologous ovarian PRP injection
- Where
- Bulgaria
- Volunteers
- 66 people
- Sponsor
- Nadezhda Women's Health Hospital
Pain
Platelet-rich-plasma Treating Tennis Elbow
The study is to compare the efficacy of autologous platelet concentrate injections to corticosteroid injection in patients suffering from tennis elbow with respect to pain and function.
- Trial name
- NCT00757289
- Testing
- PRP Injection, Corticosteroid Injection
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Zimmer Biomet
Temporomandibular Joint Osteoarthritis
Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder
Temporomandibular joint (TMJ) disorders are health conditions that can occur at any age and are recognized as the most common cause of chronic pain, affecting 5-12% of the population.
- Trial name
- NCT06839326
- Testing
- Autologous Conditioned Serum, Genesis Biyomedikal, Sanakin®-Acrs produce, Platelet Rich Plasma, Control Group/ Only Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Batman University