Clinical trials: Platelets
Impacted Third Molar Tooth
Investigation of the Effects of H-PRF on the Period After Impacted Third Molar Tooth Extraction
After wisdom teeth are extracted, the patient may have some complaints in the post-operative period. Pain, swelling and edema are some of them.
- Trial name
- NCT06244797
- Testing
- L-PRF and H-PRF, Impacted Tooth Removal
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- esengul sen
Periodontitis
Growth Factors Release of PRF and PRGF
Background: platelet concentrate could enhance growth factors (GF) crevicular fluid levels which might be crucial to proper tissue repair and wound healing.
- Trial name
- NCT02447510
- Testing
- group 1 bio-oss bone xenograft, group 2 platelet rich in growth factor (autogenous platelet rich in growth factor), group 3 platelet rich fibrin (autogenous platelet rich fibrin)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Taste, Non-esterified Fatty Acids
Free Fatty Acids: Threshold Repeatability Study
This study seeks to determine if non-esterified fatty acid (NEFA) taste detection thresholds change with repeated testing. Threshold testing for NEFA taste has been reported by a number of laboratories, including our own…
- Trial name
- NCT01550120
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Purdue University
Thrombocytopenia, Neonatal
Neonatal Platelet Transfusion Threshold Trial
The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion threshold, compared to a higher threshold, improves survival without…
- Conditions
- Thrombocytopenia, Neonatal, Platelet Transfusion, Infant, Newborn, Diseases
- Trial name
- NeoPlaTT (NCT06676904)
- Testing
- Higher Platelet Transfusion Threshold, Lower Platelet Transfusion Threshold
- Where
- 20 sites in United States
- Volunteers
- 2,433 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Gingival Overgrowth
The Effect of Platelet-Rich Plasma on Wound Healing After Gingivectomy
The aim of the study is to evaluate the effects of using droplet-form platelet-rich plasma (PRP), known to have positive effects during the intermediate healing process, on wound healing in areas left for secondary healing after…
- Trial name
- PRP (NCT07124143)
- Testing
- PRP
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Duygu Kilic
Intrabony Periodontal Defects
Minimally Invasive Non Surgical Treatment Using Injectable Platelet Concentrate in Treatment of Deep Pockets.
The purpose of this study is to evaluate change in pocket depth following using minimally invasive non surgical combined with injectable platelet concentrate .
- Trial name
- NCT07722390
- Testing
- Injectable PRF, MINST
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
The study aims to test the non-inferiority of an Allogenic Dermal Matrix with Platelet-Rich Fibrin for treatment of gingival recessions in comparison to the Connective Tissue Graft.
- Trial name
- NCT05819515
- Testing
- Tunneled coronally advanced flap
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiovascular Disease
Postprandial Effects of Walnut Components Versus Whole Walnuts on Cardiovascular Disease (CVD) Risk Reduction
The purpose of this study is to evaluate the acute, postprandial effects and mechanism of action of various walnut components (separated nut skins, de-fatted nut meat, nut oil) versus whole walnuts on oxidative stress…
- Trial name
- NCT00938340
- Testing
- Walnut "meat", Walnut Oil, Walnut Skins
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiovascular Disease
Dark Chocolate and Platelet Function in Humans
Cardiovascular disease is a major cause of mortality worldwide and responsible for one out of three global deaths. A main characteristic of cardiovascular disease is impaired blood flow and formation of blood clots.
- Trial name
- NCT01099150
- Testing
- Dark chocolate enriched in flavan-3-ols and procyanidins, Standard dark chocolate, White chocolate
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Impacted Mandibular Third Molar, Alveolar Bone Loss
Healing of Mandibular Third Molar Extraction Sockets Using Platelet Concentrates and Photobiomodulation
Surgical removal of impacted mandibular third molars is a common procedure that may be associated with postoperative pain, swelling, limited mouth opening, and delayed bone healing.
- Conditions
- Impacted Mandibular Third Molar, Alveolar Bone Loss, Impacted Mandibular Third Molar Extraction
- Trial name
- NCT07324213
- Testing
- Mandibular Third Molar Extraction With Primary Wound Closure, Autologous Platelet Concentrates, Photobiomodulation
- Where
- Poland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Healthy Volunteers
Anti-Platelet Drugs and Brain-derived Neurotrophic Factor (BDNF) in Human Serum and Plasma
The impact of anti-platelet drugs on the concentrations of Brain-derived neurotrophic factor (BDNF) in human plasma and serum is unknown.
- Trial name
- NCT01264640
- Testing
- Aspirin and Clopidogrel
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Rostock
Stress Urinary Incontinence, Urinary Incontinence
The Role of Platelet Rich Plasma Injections in Cases of Stress Incontinence
Urinary incontinence can impact on one's social, physical, mental, and sexual wellbeing, and lead to depression and social isolation Stress urinary incontinence (SUI) refers to the involuntary leakage of urine accompanying…
- Trial name
- NCT05295420
- Testing
- platelet rich plasma
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Ovary; Anomaly, Infertility, Female
Autologous Platelet-Rich Plasma Intra-ovarian Infusion in Poor Responders
Autologous PRP intra ovarian infusion may improve ovarian response, patients' hormonal profile as well as fresh embryo transfer (ET)-ICSI cycles' outcome in patients presenting with Poor Ovarian Response (POR).
- Trial name
- PRP (NCT03937661)
- Testing
- PRP
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Prehypertension, Healthy
Effects and Mechanisms of Melatonin on Blood Pressure, Insulin Resistance, and Platelets
The investigators will be studying the effect of melatonin on blood pressure, insulin resistance, and platelets, along with possible reasons for how melatonin cases these effects.
- Trial name
- NCT03178396
- Testing
- melatonin
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Hypertension
Does Ultraviolet Irradiation Reduce Platelet Reactivity and Improve Coronary Microvascular Function in Man?
Endothelium derived nitric oxide (NO) regulates vascular tone and blood pressure in man. NO also inhibits platelet aggregation and mediates a variety of beneficial anti-inflammatory and repair mechanisms.
- Trial name
- NCT01785511
- Testing
- UVA Radiation
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Tooth Extraction
The Clinical and Biological Effects of Leucocyte and Platelet-rich Fibrin (L-PRF) on Post-extraction Sockets Healing
This study evaluates the clinical and biological effects of leucocyte and platelet-rich fibrin (L-PRF) on post-extraction sockets healing.
- Trial name
- NCT03985033
- Testing
- leucocyte and platelet-rich fibrin (L-PRF)
- Where
- Hong Kong
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Von Willebrand Disease
Collection of Blood in Normal Subjects and Subjects With Von Willebrand Disease (VWD)
Von Willebrand disease is an inherited bleeding disorder that impacts the blood's ability to clot properly. Von Willebrand disease is cause by the lack or not working substance in the blood known as Von Willebrand factor.
- Trial name
- NCT00630448
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Painful Bladder Syndrome (PBS), Interstitial Cystitis
Submucosal Intravesical Injection of Platelet-rich Plasma in the Treatment of Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is characterized by a constellation of bladder symptoms, including urinary frequency, urgency, nocturia, and pelvic pain.
- Trial name
- PRP (NCT06209008)
- Testing
- Intravesical injection of Platlet Rich Plasma (PRP)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Arterial Thrombosis
Study on the Thrombolytic Effect of Platelet Membrane Coated Recombinant Staphylokinase on Human Arterial Thrombus
Recombinant staphylokinase (r-SAK) is a third-generation thrombolytic agent produced by genetic engineering technology in 1985, which has better thrombolytic effect than streptokinase (SK) and urokinase (UK).
- Trial name
- NCT05978791
- Testing
- collection of venous blood or arterial blood
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Lichen Planus
Use of Injectable Platelet Rich Fibrin in Lichen Planus
Platelet Rich Fibrine (PRF), which promotes wound healing by supporting angiogenesis, immunity and epithelial proliferation phases.
- Trial name
- NCT03265093
- Testing
- Platelet Rich Fibrin Injection, Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University