Clinical trials: Platelets Rich Plasma
Cornea Ulcer
Platelet Rich Plasma as a Treatment For Resistant Corneal Ulcers
This prospective study involved 14 patients aged > 18 years with RCUs not responding to conventional treatment. All patients were treated with E-PRP drops (one drop), preservative-free artificial tears, antibiotic eye drop four…
- Trial name
- NCT05515731
- Testing
- Autologous platelet-rich plasma (PRP) eye drops
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Alaa Gamal
Osteoarthritis
Blood Loss Reduction After Total Knee Arthroplasty. Comparison Topical Tranexamic Acid vs Platelet Rich Plasma
The investigators will include patients who will be schedule for total knee arthroplasty with a diagnosis of osteoarthritis. The patients will be divided in two groups.
- Trial name
- NCT02650856
- Testing
- Group 1 Tranexamic Acid, Group 2 Platelet rich plasma
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Mixed Urinary Incontinence
Assessment of Platelet Rich Plasma Injection in Managing Female Patients Complaining of Mixed Urinary Incontinence (PRP)
The goal of this clinical trial is to assess the efficacy of platelet-rich plasma (PRP) for the treatment of mixed urinary incontinence determine .The main question it aims to answer whether PRP is it safe and effective in…
- Trial name
- PRP (NCT06769074)
- Testing
- Platelet Rich Plasma
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Zagazig University
Hypospadias
Comparison Of Outcome Of Different Layers in Hypospadias Surgery
To compare the outcome of applying autologous platelet-rich plasma membrane layer and dartos fascial flap versus only dartos fascial flap in mid and distal penile hypospadias surgery.
- Trial name
- NCT06275646
- Testing
- PRP layer, dartos flap
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Hip Osteoarthritis
Platelet Rich Plasma Versus Corticosteroids in Hip Osteoarthritis Pain
Prospective, single-center that may go on to being multicenter, randomized trial comparing platelet rich plasma (PRP) versus corticosteroid injection for the treatment of symptoms of Hip osteoarthritis.
- Trial name
- NCT06793982
- Testing
- Platelet Rich Plasma Joint Injection, Corticosteroid Injection
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- LifeBridge Health
Femoroacetabular Impingement, Chondral Lesions
Efficacy of PRP (Platelet Rich Plasma) Following Arthroscopic Microfracture of Chondral Lesions of the Hip
The purpose of this research project is to assess the effectiveness of intra-articular injections of autologous platelet-rich plasma (PRP) after arthroscopic microfracture.
- Trial name
- NCT02183896
- Testing
- Platelet-rich plasma (PRP), Saline
- Where
- United States
- Sponsor
- University of Colorado, Denver
Osteoarthritis
The Effect of Platelet-rich Plasma in Patients With Osteoarthritis of the Knee
Osteoarthritis is the most common type of arthritis. The prevalence of osteoarthritis of the knee has significantly elevated in the elderly population and youth due to age and sport activities respectively.
- Trial name
- NCT01926327
- Testing
- PRP injection
- Where
- Iran
- Volunteers
- 150 people
- Sponsor
- Royan Institute
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Perianal Fistula
FiLaC and PRGF-Endoret for Multi-recurrent Cryptoglandular Perianal Fistula (PLASMA Pilot Study)
Multi-recurrent cryptoglandular perianal fistula represents a challenging clinical problem with no established surgical solution after repeated failures.
- Trial name
- PLASMA (NCT07810075)
- Testing
- Laser ablation of fistula tract using 1000-µm radial fibre (Biolitec, 1470 nm, 12 W, continuous, 1 mm/s withdrawal). Internal opening closed with Vicryl 2/0 suture in all patients
- Volunteers
- 25 people
- Sponsor
- Complejo Hospitalario Universitario de Santiago
Thumb Osteoarthritis
Thumb Base Osteoarthritis: Ultrasound-guided Platelet-rich Plasma Versus Placebo Injection
The goal of this clinical trial is to evaluate whether platelet-rich plasma (PRP) injections improve pain and function in adults with thumb base osteoarthritis (CMC-I OA).
- Trial name
- Thumbs-up (NCT07491302)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Saline (0.9% NaCl)
- Where
- Netherlands
- Volunteers
- 88 people
- Sponsor
- Goed Medisch Centrum
Erectile Dysfunction With Diabetes Mellitus
Combining Shockwave Therapy and Platelet Rich Plasma to Treat Erectile Dysfunction in Diabetic Men (COCKTAIL-DM)
The purpose of this research study is to evaluate whether the combination of Shockwave Therapy (SWT) with Platelet Rich Plasma (PRP) is synergistic and can reverse the pathology of microvascular Erectile Dysfunction (ED) and…
- Trial name
- COCKTAIL-DM (NCT05525572)
- Testing
- Shockwave Therapy (SWT), Autologous Platelet-Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Miami
Erosive Oral Lichen Planus
Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus
After signing the informed consent, the participant will be allocated to either intervention or control group, then each participant in the intervention group will receive intralesional injections of platelet rich plasma…
- Trial name
- NCT03293368
- Testing
- Platelet rich plasma, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Rotator Cuff Tears
Platelet Rich Plasma on Rotator Cuff Repair
Repair of the rotator cuff has high rates of re-rupture (20-54%), despite good clinical results. Several ways to improve the healing tendon-bone are currently studied, among them the most used is the use of growth factors.
- Trial name
- PRP (NCT01029574)
- Testing
- Platelet rich plasma
- Where
- 2 sites in Brazil
- Volunteers
- 54 people
- Sponsor
- University of Sao Paulo
Lower Extremity, Chronic Ulcers
Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Lower Extremity Ulcers
To prospectively evaluate the safety and efficacy of an Autologous Platelet-Rich Fibrin Plasma system when applied in conjunction with Standard of Care for management of chronic lower extremity wounds.
- Conditions
- Lower Extremity, Chronic Ulcers, Pressure Ulcer (PU), Venous Leg Ulcer (VLU)
- Trial name
- NCT07862335
- Testing
- PRFM
- Volunteers
- 30 people
- Sponsor
- Tiger Biosciences, LLC.
Vulvo Vaginal Atrophy
Regenerative Treatment of Female Genital Atrophy
Vulvovaginal health is a key aspect of active and healthy aging for all women. Hormonal deprivation that occurs during menopause significantly affects the anatomy and function of urogenital tissues, leading to their atrophy.
- Trial name
- RETREAT-FUGA (NCT07306611)
- Testing
- Mesotherapy with Autologous Platelet-Rich Plasma (PRP) to vulvovaginal area, Mesotherapy with saline solution, Platelet-Poor Plasma Gel
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- AndreiaAntunes
Chronic Patellar Tendinopathy, Chronic PT
Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar Tendinopathy
The goal of this study is to find an effective treatment for chronic patellar tendinopathy (PT). Investigators will conduct a 32-week randomized controlled clinical trial to determine whether platelet rich plasma (PRP) injections…
- Trial name
- PRP (NCT01843504)
- Testing
- platelet rich plasma, saline
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Tendinopathy, Hip Pain
Platelet-rich Plasma vs. Whole Blood for Gluteus Medius Tendinopathy
Gluteus medius tendinopathy, which is often referred to as Greater Trochanteric Pain Syndrome, is characterized by pain in the lateral aspect of the hip that is aggravated by side lying, stair climbing, and walking.
- Trial name
- NCT02978833
- Testing
- PRP, Whole Blood, Ultrasound
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis, Knee
Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA
ABLE OA is a Health Canada authorized (phase II/III) trial [Parent Control #: 263591]. A multi-center, prospective, double-blinded, randomized, placebo-controlled adaptive trial to evaluate the efficacy of two minimally…
- Trial name
- ABLE-OA (NCT05517434)
- Testing
- Bone Marrow Aspirate (BMA): Minimally manipulated autologous cellular preparation, Lipoaspirate Micronized + Leukocyte-Poor Platelet-Rich Plasma (LAM + LP-PRP): Minimally manipulated autologous cellular preparations
- Where
- 2 sites in Canada
- Volunteers
- 148 people
- Sponsor
- University Health Network, Toronto
Aging
Split Face Study of the Effects of Micro Needling With and Without Platelet Rich Plasma
This pilot study will expand knowledge and application of 2 X concentration of Platelet Rich Plasma (PRP) in conjunction with microneedling using the SkinPen device.
- Trial name
- NCT04219293
- Testing
- Microneedling w/ and w/o PRP
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Dallas Plastic Surgery Institute