Clinical trials: Platelets Rich Plasma
Ankle Osteoarthritis
A Single Intraarticular Injection of Platelet-Rich Plasma on Pain and Physical Function in Patients With Ankle OA
Platelet-rich plasma (PRP) has been reported to be an effective treatment for knee osteoarthritis (OA). The application in ankle OA has rarely been investigated.
- Trial name
- NCT04022928
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Femoroacetabular Impingement
Platelet-rich Plasma Versus Corticosteroid Injection for the Treatment of Femoroacetabular Impingement
The purpose of this study is to compare the clinical response of intra-articular platelet rich plasma (PRP) versus corticosteroid injection in patients affected by femoroacetabular impingement (FAI).
- Trial name
- NCT02920177
- Testing
- platelet-rich plasma injection, Kenalog 10 MG/ML Injectable Suspension
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Pilonidal Disease, Pilonidal Sinus
Effect of Platelet Rich Plasma (PRP) on Healing Time in Patients Following Pilonidal Sinus Surgery
Our study was planned as a prospective controlled randomized study. The study was started after the ethics committee approval received from Dışkapı Yıldırım Beyazıt Training and Research Hospital. (23.08.2021 118/01).
- Trial name
- NCT06206330
- Testing
- Platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- İsmail Oskay Kaya
Epicondylitis
Platelet Rich Plasma (PRP) in Chronic Epicondylitis
Background Tendinopathy is a difficult problem to manage and can result in significant patient morbidity. Currently, the clinical use of PRP in painful tendons is widespread but its efficacy remains controversial.
- Trial name
- B-PRPtendon (NCT01945528)
- Testing
- US-guided tenotomy with PRP, US-guided tenotomy with lidocaine
- Where
- 2 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Jose Ignacio Martin
Burns
Autologous Platelets Concentrate and Autologous Thrombin for the Treatment of Deep Burn Trauma
Deep skin burn injuries, especially extensive deep burns or/and deep burns extending on the face, hands, feet, genitalia and perineum, remain one of the most challenging therapeutic problems.
- Trial name
- NCT01383187
- Testing
- DE graft and PRP concentrate, DE graft
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital Ostrava
Dry Eye Disease
Comparison of Efficacy Between 100% Platelet-rich Plasma and 100% Serum Eye Drops in Dry Eye Disease
Dry eye disease (DED) is a common eye problem, affecting 5% to 50% of the world population. Although the disease is not fatal, it substantially reduces quality of life and creates a high economic burden as high as over 50 billion…
- Trial name
- NCT04683796
- Testing
- 100% Autologous platelet rich plasma, 100% Autologous serum
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Platelet-Rich Plasma, Meniscus Lesion
Platelet-rich Plasma for Menical Tear
Meniscal injuries are a common pathology among athletes, and have an impact on the daily or sporting practice of patients. Surgical approach implies sometimes heavy consequences.
- Trial name
- NCT04040283
- Testing
- Platelet-rich plasma (PRP) therapy
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- University of Malaga
Diabetic Neuropathies, Chronic Pain
Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain
Peripheral neuropathy is very common in diabetes mellitus (DM). Till now there is no available effective therapy for this pathology.
- Trial name
- NCT03601494
- Testing
- perineural injection of platelet-rich plasma, medical
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Chronic Low Back Pain
Intra-discal Injection of PRP for Low Back Pain
Low back pain (LBP) is the second cause of medical visits in France. Indeed, its incidence can vary between 60 and 90%. LBP is also the leading cause of disability in the adult population in France and in the rest of the world.
- Trial name
- MODI-PRP (NCT03712527)
- Testing
- Injection of Platelet rich plasma, Injection of NaCl
- Where
- 6 sites in France
- Volunteers
- 126 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer, Lipofilling
Evaluation of the Efficacy and Safety of Using Platelet-rich Fibrin (PRF)-Based Lipobolus for the Immediate Reconstruction of Defects After Breast-conserving Resection for Breast Cancer (Minimally Invasive Primary Immediate Grafting)
The goal of this clinical trial is to learn if a special type of fat graft, made by mixing a person's own fat with platelet-rich fibrin (PRF), works to fix breast shape defects after cancer surgery.
- Conditions
- Breast Cancer, Lipofilling, Fat Graft, Platelet Rich Plasma
- Trial name
- MINIPIG (NCT07658170)
- Testing
- Lipobolus (Autologous Fat + Platelet-Rich Fibrin+Calcium chloride)
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- The Leningrad Regional Clinical Hospital
Ganglion of Wrist
Dorsal Wrist Ganglia; Aspiration Alone vs Aspiration and Injection of Platelet Rich Plasma
Study to examine the efficacy of Platelet Rich Plasma (PRP) to reduce recurrence in dorsal wrist ganglia (DWG). We will compare aspiration alone and aspiration with injection of PRP. We plan to recruit a maximum of 200 patients.
- Trial name
- NCT03408808
- Testing
- Platelet rich plasma, Aspiration alone
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Aberdeen
Androgenetic Alopecia
Activated PRP for Treatment of Androgenetic Alopecia
A clinical trial to assess the effects and safety of PRP activated with pulsed electrical fields (PEFA-PRP) compared with unactivated PRP when used to treat AGA.
- Trial name
- NCT05348343
- Testing
- Autologous platelet-rich plasma
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Santiste Medical Inc.
Chronic Non-healing Skin Ulcers
PRP Versus PRF Versus Conventional Treatment in Chronic Non-healing Skin Ulcers
To compare the therapeutic efficacy of PRP and PRF: two relatively newer modalities in the management of chronic non-healing ulcers versus conventional treatment.
- Trial name
- NCT06281483
- Testing
- platelet-rich plasma, platelet-rich fibrin, Surgical debridement, normal saline washing and dressing coverage
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kafrelsheikh University
Tennis Elbow, PRP
ECRB Tendinopathy: Needling ± PRP After Failure of Rehabilitation
This study evaluates the effect of platelet-rich plasma (PRP) use during needling of the extensor carpalis radialis brevis tendon, after failure of proper reeducation including focal extra-corporal shockwave therapy (ESWT).
- Conditions
- Tennis Elbow, PRP, Tendinopathy, Tendinosis
- Trial name
- NCT03987256
- Testing
- Initial rehabilitation protocol, Needling with PRP, Needling with saline solution
- Where
- Switzerland
- Volunteers
- 58 people
- Sponsor
- Adrien Schwitzguebel
Periodontal Diseases, Gingival Recession Localized Moderate
Hydroxyapetite Nanoparticles and Tricalcium Phosphate Nanoparticles Loaded on Platelet Rich Fibrin Membranes for Treatment of Gingival Recession
The "Glossary of the American of Periodontology" defines gingival recession (GR) as the apical movement of the gingival margin beyond the cement-enamel junction.
- Conditions
- Periodontal Diseases, Gingival Recession Localized Moderate, Nano-hydroxyapatite, Nano Tricalcium Phosphate
- Trial name
- NCT07088809
- Testing
- Nanocrystalline hydroxyapatite loaded in PRF+ coronally advanced flap, Nanocrystalline tricalcium phosphate (NcTCP) loaded in PRF+ coronally advanced flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Enas Elgendy
Gonarthrosis
Exercise vs. Topical Diclofenac vs. PRP
Osteoarthritis, the most common type of arthritis, is a chronic and degenerative joint disease. It has been reported to affect more than 300 million adults and elderly individuals worldwide.
- Trial name
- NCT05877027
- Testing
- Exercise, Topical Diclofenac, Platelet-Rich-Plasma (PRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Istanbul University - Cerrahpasa
Hip Osteoarthritis
Platelet-Rich Plasma and Hip Osteoarthritis
To evaluate the effect of platelet-rich plasma (PRP) injection on pain, function and quality of life in patients with hip osteoarthritis.
- Trial name
- NCT04820231
- Testing
- intra-articular PRP injection
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Erectile Dysfunction
Combined Treatment of Platelet-rich Plasma (PRP) and Low-intensity Extracorporeal Shockwave Therapy (Li-ESWT) on Erectile Dysfunction (ED)
The purpose of this clinical study is mainly to use platelet-rich plasma combined with low-intensity extracorporeal shockwave therapy to treat patients with erectile dysfunction and observe the improvement results.
- Trial name
- NCT04416802
- Testing
- autologous platelet-rich plasma and low-intensity extracorporeal shockwave therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Taipei Medical University Hospital
PRP
"Platelet-Rich Plasma" Epidural Injection an Emerging Strategy in Lumbar Disc Herniation
To evaluate the efficacy of platelet-rich plasma (PRP; double-spin) in treatment of single-level lumbar herniated nucleus pulposus (HNP) in comparison to triamcinolone. RCT was conducted with 30 patients included.
- Trial name
- NCT05234840
- Testing
- platelet rich plasma, Triamcinolone
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Vitiligo
Platelet-rich Plasma Intradermal Injection Combined With 308 nm Excimer Light for Treating Stable Acral Vitiligo
The goal of this clinical trial is to learn if platelet-rich plasma (PRP) works to treat acral stable vitiligo in adults. It will also learn about the safety of platelet-rich plasma.
- Trial name
- NCT06394349
- Testing
- PRP+308nm, NS+308nm
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Yijian Zhu