Clinical trials: Pneumocystis
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Trimetrexate With Leucovorin Rescue for AIDS Patients Who Are Refractory to Standard Therapies for Pneumocystis Carinii Pneumonia
To study the safety and effectiveness of trimetrexate (TMTX) plus leucovorin calcium rescue (LCV) in the treatment of Pneumocystis carinii pneumonia (PCP) in patients who have AIDS, patients who are HIV positive, or those for…
- Trial name
- NCT00000724
- Testing
- Trimetrexate glucuronate, Leucovorin calcium
- Where
- United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pneumonia, Fungal Pneumonia
Derivation and Validation of the Fungal Pneumonia Assessment and Likelihood Predictor Score
The FUNGAL-P study is a single-center observational study designed to derive and validate a clinical prediction score for the early identification of fungal pneumonia in adult patients presenting with pneumonia.
- Conditions
- Pneumonia, Fungal Pneumonia, Aspergillosis Pneumonia, Pulmonary Aspergillosis
- Trial name
- FUNGAL-P (NCT07681583)
- Testing
- FUNGAL-P Score Assessment
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Multiple Myeloma
Pomalidomide, Cyclophosphamide and Prednisone (PCP) in Patients With Multiple Myeloma (MM) Relapsed and/or Refractory to Lenalidomide
This study will evaluate if the combination of Pomalidomide, Cyclophosphamide and Prednisone is safe and provides benefits in patients with multiple myeloma relapsed and/or refractory to lenalidomide.
- Trial name
- PCP (NCT01166113)
- Testing
- Pomalidomide, Cyclophosphamide, Prednisone
- Where
- Italy
- Volunteers
- 67 people
- Sponsor
- Fondazione EMN Italy Onlus
Pneumonia, Pneumocystis Carinii, HIV Infections
Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms
To confirm the ability of pulmonary (lung) function testing (PFT) to detect Pneumocystis carinii pneumonia (PCP) before the development of clinical symptoms and to determine if pentamidine (PEN), a drug used in treating PCP, can…
- Trial name
- NCT00000707
- Testing
- Pentamidine isethionate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Emphysema
Prevalence and Pathogenesis of Lung Disease in a Large HIV Cohort-coordinating Center
Despite the availability of highly active antiretroviral therapy (HAART), lung diseases remain a leading cause of morbidity and mortality in those with HIV infection.
- Conditions
- HIV Infections, Emphysema, Chronic Obstructive Pulmonary Disease, Pneumocystis
- Trial name
- MACS (NCT00870857)
- Where
- 2 sites in United States
- Volunteers
- 407 people
- Sponsor
- University of Pittsburgh
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study to Evaluate the Impact of Stopping Treatment for the Prevention of Pneumonia in HIV-Positive Patients Receiving Anti-HIV Drugs Who Have Increased CD4 Cell Counts
The purpose of this study is to see how often Pneumocystis carinii pneumonia (PCP) occurs in HIV-positive patients who have stopped taking medications that help prevent PCP.
- Trial name
- NCT00000908
- Where
- 54 sites in United States, Puerto Rico
- Volunteers
- 250 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pneumonia, Pneumocystis, Coronavirus
Efficacy and Safety of Hydroxychloroquine for Treatment of COVID-19
The study aims to evaluate the efficacy and safety of hydroxychloroquine in the treatment of COVID-19 pneumonia.
- Conditions
- Pneumonia, Pneumocystis, Coronavirus, COVID-19
- Trial name
- NCT04261517
- Testing
- Hydroxychloroquine
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Shanghai Public Health Clinical Center
Pneumonia, Pneumocystis Carinii, HIV Infections
A Treatment Protocol for the Use of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia and Serious Intolerance to Approved Therapies
To determine the safety and effectiveness of an investigational drug trimetrexate (TMTX) with leucovorin rescue (LCV) in the treatment of Pneumocystis carinii pneumonia (PCP) in patients who have AIDS, are HIV positive, or are at…
- Trial name
- NCT00001016
- Testing
- Trimetrexate glucuronate, Leucovorin calcium
- Where
- United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pneumonia, Pneumocystis, Autoimmune Inflammatory Rheumatic Disease
Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Disease
This is an open-labeled, prospective clinical study aims at collecting and analyzing baseline characteristics of autoimmune inflammatory rheumatic disease (AIIRD) patients receiving sulfanilamide for preventive purposes, as well…
- Conditions
- Pneumonia, Pneumocystis, Autoimmune Inflammatory Rheumatic Disease, Autoimmune Diseases, Connective Tissue Disease
- Trial name
- NCT06499233
- Testing
- Trimethoprim/Sulfamethoxazole
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Tongji Hospital