Clinical trials: Pneumocystis Jirovecii Pneumonia in Non-HIV Patients
Pneumocystis Jiroveci Pneumonia
Corticosteroids for PJP in Non-HIV Immunocompromised Adults
Pneumocystis jirovecii pneumonia (PJP) is one of the common severe complications in immunocompromised patients, with a reported mortality rate of 60-80%.
- Trial name
- CAPSTONE-PJP (NCT07152613)
- Testing
- Saline (0.9%, sterile, for infusion), Low Dose Corticosteroids, Moderate dose corticosteroids
- Volunteers
- 240 people
- Sponsor
- Qingyuan Zhan
Pneumocystis Pneumonia
Effects and Safety of Caspofungin and Corticosteroids in Pneumocystis Pneumonia in Non-HIV Patients
Pneumocystis Pneumonia is increasing in Immunocompromised Non-HIV Infected Patients. The effects and safety of caspofungin and corticosteroids is not certain in this population.
- Trial name
- NCT02603575
- Testing
- caspofungin, corticosteroids, Sulfanilamides
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Chao Yang Hospital
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP
To evaluate the safety and effectiveness of trimetrexate (TMTX) given at increasing doses along with the leucovorin calcium (LCV) for treating Pneumocystis carinii pneumonia (PCP) in AIDS patients TMTX is an experimental new drug…
- Trial name
- NCT00000998
- Testing
- Trimetrexate glucuronate, Leucovorin calcium
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pneumocystis Jirovecii Pneumonia
Radiomics Model for the Diagnosis of Pneumocystis Jirovecii Pneumonia in Non-HIV Patients
To evaluate the performance of radiomics in differentiating Pneumocystis jirovecii pneumonia (PCP) from other types of pneumonia and to improve the diagnostic efficacy of non-invasive tests in non-HIV patients.
- Trial name
- NCT05701631
- Testing
- Radiomic model
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Chinese PLA General Hospital
Pneumocystis
Pneumocystis in Patients Over 75 Year
Pneumocystis pneumonia is an infectious disease caused by Pneumocystis jirovecii that affects the lung parenchyma preferentially. Historically described in an immunocompromised population through HIV.
- Trial name
- C_PAPY (NCT07004127)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pneumocystis Jirovecii Infection
Pneumocystis Jirovecii Pneumonia in Non-HIV-infected Immunocompromised Patients
Pneumocystis jirovecii pneumonia (PjP) is a rare infectiouse disease with a high level of mortality. PjP is a classical opportunistic infection which concern HIV infected and immunocompromised patients.
- Trial name
- PnP-HIV-Free (NCT05458752)
- Where
- France
- Volunteers
- 133 people
- Sponsor
- Central Hospital, Nancy, France
Pneumocystis Pneumonia
Trimethoprim/Sulfamethoxazole Combined With Caspofungin as First-line Therapy in PCP
This is a prospective, randomized clinical trial. During the study, non-HIV patients who are admitted to ICU due to Pneumocystic pneumonia (PCP) and have not received anti-PCP therapy or have received therapy less than 48hrs will…
- Trial name
- NCT03978559
- Testing
- caspofungin, TMP/SMZ(trimethoprim/sulfisoxazole), Methylprednisolone
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Bin Du
Pneumocystis Jirovecii Pneumonia in Non-HIV Patients
TMP-SMX for Non-HIV PCP: A Prospective Multicenter Study
Pneumocystis jirovecii pneumonia (PCP) is a life-threatening opportunistic infection in immunocompromised patients. Non-HIV-related PCP has a rising incidence, faster progression, and higher mortality than HIV-associated cases.
- Trial name
- NCT07690410
- Testing
- low-dose TMP-SMX regimen
- Volunteers
- 480 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Non-HIV Patients With Pneumocystis Jiroveci Pneumonia
Assessment of CMV-specific ELISPOT Assay for Predicting CMV Co-infection in Patients With Pneumocystitis Pneumonia (ACE-PCP)
PCP (Pneumocystis jiroveci pneumonia) is one of the important opportunistic infections in immunocompromised patients including HIV-infected patients, transplant recipients, and immunosuppressant users.
- Trial name
- NCT02109887
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Asan Medical Center