Clinical trials: Pneumonia, Aspiration
Covid19, Respiratory Disease
Post COVID19 Functional and Cognitive Assessments
The main objective of the proposed study is to evaluate the impact of coronavirus (2019-nCoV), hereafter COVID -19, on patients' loss of functional capacity after completion of hospital treatment.
- Conditions
- Covid19, Respiratory Disease, Walking, Difficulty, Cognitive Decline
- Trial name
- PostCovidZRS (NCT04860206)
- Where
- Slovenia
- Volunteers
- 43 people
- Sponsor
- Science and Research Centre Koper
Ventilator Associated Pneumonia, Morality
Endotracheal Tube Cuff Pressure Measurement
The effect of endotracheal cuff pressure measurement technique for preventing ventilatory associated pneumonia.
- Conditions
- Ventilator Associated Pneumonia, Morality, Trauma, Brain, Endotracheal Aspiration
- Trial name
- NCT04397952
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bagcilar Training and Research Hospital
COVID-19 Infection
Clazakizumab vs. Placebo - COVID-19 Infection
The purpose of this study is to investigate the effectiveness and safety of treatment with clazakizumab compared to a placebo (inactive substance).
- Trial name
- NCT04494724
- Testing
- Clazakizumab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Methodist Hospital Research Institute
Rapid Sequence Induction of General Anesthesia, Sellick Maneuver
Sellick Interest in Rapid Sequence Induction
Lung aspiration can occur when a rapid sequence induction of anesthesia is performed (emergency and/or presence of at least one risk factor for regurgitation of stomach contents).
- Conditions
- Rapid Sequence Induction of General Anesthesia, Sellick Maneuver, Acid Aspiration Syndrome, Lung Aspiration
- Trial name
- IRIS (NCT02080754)
- Testing
- effective sellick maneuver
- Where
- France
- Volunteers
- 3,472 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pneumonia
Effect of Pursed-Lip Breathing on Physiological Parameters and Discharge Readiness in Children With Pneumonia
This study aims to evaluate the effects of Pursed-Lip Breathing (PLB) exercises on physiological parameters (such as respiratory rate, heart rate, and oxygen saturation) and discharge readiness in children diagnosed with…
- Trial name
- PLB-PEDPNEU (NCT07106203)
- Testing
- Pursed-Lip Breathing (PLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk University
COVID-19
IH Convidecia as Second Booster Dose Against Breakthrough Infections
This will be a randomized single-blind controlled trial to determine the immunogenicity, efficacy and safety of IH Convidecia (CanSino), as a second booster vaccination against Omicron and other emerging VOCs to prevent…
- Trial name
- NCT05517642
- Testing
- Recombinant COVID-19 vaccine (adenovirus type 5 vector) for Inhalation (Ad5-nCoV-IH), mRNA vaccine BNT162b2 (Pfizer)
- Where
- Malaysia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia
Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure
This prospective observational study will evaluate the safety and performance of the MiniLung petite kit in neonatal and pediatric patients with acute respiratory and cardiac failure.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia, Acute Respiratory Failure, Acute Lung Injury
- Trial name
- PETIT (NCT06750536)
- Testing
- MiniLung petite kit combined with the Xenios console
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Xenios AG
Pneumonia, Aspiration
The Clinical Application Value of "Showering Cells" in the Diagnosis of Aspiration Pneumonia
Based on our team's previous discovery of a unique type of squamous epithelial cell in the bronchoalveolar lavage fluid (BALF) of patients with aspiration pneumonia (AP) using microbiological rapid on-site evaluation (M-ROSE)…
- Trial name
- NCT07395310
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Chinese PLA General Hospital
COVID-19
Inhaled Ivermectin and COVID-19
Coronavirus disease-19 is global healthcare crisis. Till May 20, 2020, there were approximately 4,789,205 cases and 318,789 related mortalities were identified globally.
- Trial name
- CCOVID-19 (NCT04681053)
- Testing
- Ivermectin Powder
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulmonary Infection, Respiratory Insufficiency
Change of Regional Ventilation During Spontaneous Breathing After Lung Surgery
Perioperative changes in regional ventilation by pulmonary electrical impedance tomography and spirometry will be investigated in patients at risk for postoperative pulmonary complications.
- Conditions
- Pulmonary Infection, Respiratory Insufficiency, Aspiration Pneumonitis, Bronchospasm
- Trial name
- NCT02779595
- Testing
- Perioperative pulmonary function tests
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Wuerzburg University Hospital
Pneumonia, Aspiration, Anesthesia
Evaluation of Gastric Content of Volunteers Fasting and Using Semaglutide: an Observational and Cross-sectional Study
Medicines with peptide-1 receptor agonist action similar to glucagon (GLP-1) are a modern therapeutic option for obesity and diabetes mellitus.
- Trial name
- NCT06154486
- Testing
- semaglutide use
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital Israelita Albert Einstein
Ventilation Acquired Pneumonia
The Effect of Continuous Management of Suction Cuff Pressure and Subglottic Irrigation Suction on Preventing VALRI Study
Assessing the effectiveness of continuous cuff pressure management combined with subglottic suction irrigation in reducing ventilator-associated lower respiratory tract infections (VALRTI) in mechanically ventilated patients at…
- Trial name
- SCOPE (NCT06867237)
- Testing
- Suction cuff pressure
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
Stroke, Deglutition Disorders
Effectiveness of an mHealth Intervention, Based on Rehabilitation and a Personalised Nutrition Plan, in the Recovery and Improvement of Dysphagia in Patients Diagnosed With Stroke
The goal of this clinical trial is to evaluate the efficacy of an mHealth intervention as a complement to usual clinical practice for the improvement and recovery of dysphagia in patients who have suffered a stroke.
- Trial name
- NCT07267468
- Testing
- mHealth intervention
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- University of Cadiz
Aspiration Pneumonia, Tracheostomy Complication
Intra-laryngeal Implant for Treatment of Chronic Aspirations
This study evaluates the medical device Newbreez LD is designed to protect the lower airways from saliva, liquids and food aspirations in tracheotomized patients suffering from chronic aspirations that require specific care and…
- Trial name
- NCT03325725
- Testing
- NewBreez LD intra-laryngeal implant
- Where
- 2 sites in France
- Sponsor
- ProTiP Medical
Aspiration Pneumonia, Bronchoscopy
FBS-ASaP: Fibrobronchoscopy in ASpiration Pneumonia in the Emergency Department
Non-Profit Prospective Observational Pilot Study The study will have an overall duration of 3 years, with patient enrollment starting after ethical committee approval.
- Trial name
- FBS-ASaP (NCT06511583)
- Testing
- Laryngotracheal Aspiration Procedure Using a Probe in the Emergency Department, Aspiration Procedure Using Fibrobronchoscopy in the Emergency Department
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Fasting, Delayed Gastric Emptying
Gastric Assessment of Pediatric Patients Undergoing Surgery
The goal of this pilot prospective cohort study is to examine the reproducibility of gastric volume and emptying as measured by gastric ultrasound and its correlation to a gold-standard test for gastric emptying in the…
- Conditions
- Fasting, Delayed Gastric Emptying, Aspiration Pneumonia, Respiratory Aspiration of Gastric Content
- Trial name
- NCT05674643
- Testing
- Gastric Ultrasound Baseline Scans, Acetaminophen Absorption Test (AAT), Gastric Ultrasound Serial Scans
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Lipid Pneumonia, Superoxide Dismutase
The Relationship Between Total Sialic Acid and Superoxide Dismutase and the Diagnosis and Prognosis of Lipoid Pneumonia
The goal of this observational study is to explore the correlation between total sialic acid combined with superoxide dismutase and the diagnosis and prognosis of lipid pneumonia in the patient with lipid pneumonia, cough…
- Conditions
- Lipid Pneumonia, Superoxide Dismutase, Sialic Acid
- Trial name
- NCT06430008
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Hu Yinan
Aspiration Pneumonia, Gastric Volume
Gastric Ultrasound for Preoperative Assessment of Gastric Content in Diabetic Patients
ASA fasting guidelines are only applicable to healthy elective surgery patients. Measuring gastric volume now is not easy, and scintigraphy has remained the gold standard technique for many years.
- Trial name
- NCT04181814
- Testing
- Ultrasound
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Respiratory Failure
Occurrence of Ventilator Associated Pneumonia in Italian ICU Using Cuffed Tracheostomy Tubes With Subglottic Secretion Drainage
Ventilator-associated pneumonia (VAP) is a serious complication and carries increased risks of morbidity and mortality for patients who require mechanical ventilation.
- Trial name
- VICTOR (NCT02223988)
- Testing
- subglottic secretion removal
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Turin, Italy
Covid19
Effect of Prone Position onV/Q Matching in Non-intubated Patients With COVID-19
A prospective physiologic study, in participants with COVID-19-related pneumonia requiring supplemental oxygen (standard oxygen therapy or high-flow nasal cannula (HFNC)) less than 24 hours.
- Trial name
- NCT04754113
- Testing
- prone position
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Southeast University, China