Clinical trials: Pneumonia; Pulmonary Infection
Covid-19
Characterization of Fungal Infections in COVID-19 Infected and Mechanically Ventilated Patients in ICU
Characterization of fungal infections in COVID-19 infected and mechanically ventilated patients in ICU
- Trial name
- MY-CO-VID (NCT04368221)
- Where
- 22 sites in France
- Volunteers
- 576 people
- Sponsor
- Rennes University Hospital
Music Therapy, Anxiety
The Effect of Music Therapy in COVID-19 Patients Given Prone Position
Almost half of the patients diagnosed with COVID-19 pneumonia develop ARDS and most of these patients are treated in the intensive care unit.
- Conditions
- Music Therapy, Anxiety, Respiratory Distress Syndrome, Intensive Care Units
- Trial name
- NCT05038514
- Testing
- musıc therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kutahya Health Sciences University
Covid19
The Efficacy of Nigella Sativa Versus VitaminD3 as Supplement Therapy in Coronavirus Disease 2019 (COVID-19)
The aim this study is to investigate the safety and efficacy of Nigella Sativa versus Vitamin D3 versus Nigella Sativa / vitamin D3 combination as supplement for management of COVID-19 .
- Trial name
- COVID-19 (NCT04981743)
- Testing
- Nigella Sativa capsule twice daily
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Covid19, Personal Protective Equipment
Clinical Trial on the Efficacy of Different Masks With and Without a Peripheral Sealing Device, Against Covid-19
A significant number of professionals subjected to high-risk situations have been infected by Covid-19, due to the lack of adequate respiratory protection equipment or poor marginal sealing adjustments.
- Trial name
- NCT05079308
- Testing
- Peripheral sealing device for surgical mask or filtering face piece, IIR Surgical mask with Filtering face piece
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Pulmonary Inflammation, Cytotoxicity
Pulmonary and Systemic Effects of Exposure to Wood Smoke
This is study is to assess pulmonary and systemic effects of exposure to wood smoke. Healthy volunteers will be expose under two different occasion to wood smoke and filtered air under two separated occasions with an interval of…
- Trial name
- NCT03302117
- Testing
- Wood smoke exposure
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Umeå University
Acute Respiratory Disease, COPD Exacerbation Acute
Study of Hospitalised Patients With Acute Respiratory Conditions
The goal of this observational study is to learn about the short- and long-term outcomes of people admitted to hospital with an acute respiratory condition, including exacerbations of chronic lung disease, and to understand…
- Conditions
- Acute Respiratory Disease, COPD Exacerbation Acute, Asthma, Pneumonia
- Trial name
- CHESTY (NCT05095090)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
COVID19
Association of Comorbidities With COVID19
Association of Comorbidities with unfavorable COVID19 outcomes as admission to intensive care, invasive ventilation or death.
- Trial name
- NCT04459390
- Testing
- realtime PCR
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
COVID-19
Efficacy and Safety of ES16001 in Patients With COVID-19
This is phase II/III, randomized, parallel-group, double-blind, placebo-controlled study. Patients must be at least 19 years of age (or according to the legal age for adult in each country) with confirmed mild or moderate…
- Trial name
- NCT05525182
- Testing
- ES16001 40 mg, ES16001 80 mg, ES16001 160 mg
- Where
- 3 sites in South Korea
- Volunteers
- 706 people
- Sponsor
- Genencell Co. Ltd.
Acute Respiratory Tract Infection, Flu, Human
Effectiveness of a Nasal Spray on Viral Respiratory Infections
There is no cure for cold or flu, most people recover in about within two weeks. Paracetamol may be used to reduce aches or treat fever, headache, or body aches.
- Conditions
- Acute Respiratory Tract Infection, Flu, Human, COVID-19, Common Cold
- Trial name
- NCT06278324
- Testing
- Nasal Spray HSV Treatment
- Where
- France
- Volunteers
- 76 people
- Sponsor
- CEN Biotech
COVID-19, Post COVID-19
Virtual Physical Rehabilitation for Patients Living with Long COVID
The purpose of this study is to investigate whether a timely, virtual home-based physical rehabilitation program for patients living with long COVID can improve functional mobility compared to usual care.
- Conditions
- COVID-19, Post COVID-19, Long COVID
- Trial name
- NCT05298878
- Testing
- Intervention Group: Virtual home-based rehabilitation plus usual outpatient care
- Where
- 2 sites in Canada
- Volunteers
- 132 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Aspiration Pneumonia
Nocturnal Nasal Continuous Positive Airway Pressure in Aspiration Pneumonia
Numerous elderly patients are suffering from aspiration pneumonia due to anatomical or functional predisposing factors including enteral tube feeding, swallowing difficulties, and gastroesophageal reflux disease (GERD).
- Trial name
- NAP (NCT03844568)
- Testing
- nocturnal nasal continuous positive airway pressure
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Covid19
Vaccination With COMIRNATY in Subjects With a VAXZEVRIA First Dose
CombiVacS is a phase 2 randomized, adaptive trial developed to evaluate the immunogenicity of a dose of COMIRNATY after a previous single dose of VAXZEVRIA.
- Trial name
- CombiVacS (NCT05378191)
- Testing
- COMIRNATY
- Where
- 5 sites in Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
SARS-CoV-2, COVID-19
A Study on the Safety and Immune Response of Investigational COVID-19 mRNA Vaccines in Healthy Adults
The purpose of Part A of this study is to assess the immune response and safety of a booster dose of investigational COVID-19 mRNA vaccines in healthy adults.
- Trial name
- NCT05960097
- Testing
- CV0701 mRNA COVID-19 Vaccine (Low dose), CV0701 mRNA COVID-19 Vaccine (Medium dose), CV0701 mRNA COVID-19 Vaccine (High dose)
- Where
- 17 sites in United States, Australia
- Volunteers
- 692 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Covid19
Covid-19 Virtual Recovery Study
The purpose of this study is to determine the effects of respiratory muscle training (RMT) and nasal breathing on patients who have been infected with the SARS-CoV2 virus and continue to have lingering symptoms.
- Trial name
- NCT04950725
- Testing
- Strength RMT, Strength RMT and nasal breathing, Endurance RMT
- Where
- United States
- Volunteers
- 2,268 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Mild Cognitive Impairment, Dementia
Cognitive Outcomes During COVID-19 confiNemeNt in Elderly and Their Caregivers Using Technologies for DEMentia
Coronavirus disease 2019 has forced worldwide the implementation of unprecedented restrictions to control its rapid spread and mitigate its impact.
- Trial name
- CONNECTDEM (NCT04385797)
- Testing
- Telephone interview
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Vaccine Refusal, COVID-19
Exploring the Effect of Video Interventions on Intentions for Continued COVID-19 Vaccination
While COVID-19 vaccine uptake has generally been high in Canada, with 83.4% of the total population having received the first two doses (i.e., primary series), additional "booster" uptake has been slower, especially among young…
- Trial name
- NCT05808413
- Testing
- Informational Video, Altruistic Video, Individualistic Video
- Where
- Canada
- Volunteers
- 3,567 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Sars-CoV2
Hydroxychloroquine or Diltiazem-Niclosamide for the Treatment of COVID-19
No optimal antiviral intervention has been yet validated to treat COVID-19 disease. Comorbidities, such as older age, obesity, diabetes, history of cardiovascular diseases are associated with poor prognosis.
- Trial name
- HYdILIC (NCT04372082)
- Testing
- Standard of care (SOC), Hydroxychloroquine, Association of diltiazem and niclosamide
- Sponsor
- University Hospital, Lille
Stunting, Underweight
Spirulina Supplementation and Infant Growth, Morbidity and Motor Development
Background: In developing countries, micronutrient deficiency in infants is associated with growth faltering, morbidity, and delayed motor development.
- Conditions
- Stunting, Underweight, Pneumonia, Pneumocystis, Cough
- Trial name
- NCT03523182
- Testing
- Spirulina, Control
- Where
- Zambia
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Programme Against Malnutrition
COVID-19, Immunologic Factors
Study of the Immunogenicity, Safety and Tolerability of the Convacell Vaccine.
A two-stage trial will involve healthy volunteers. The first stage is open trial, and the second stage is a double-blind trial with randomization of volunteers into three groups.
- Conditions
- COVID-19, Immunologic Factors, Coronavirus Infections, Respiratory Tract Infections
- Trial name
- NCT05156723
- Testing
- Subunit recombinant vaccine for the prevention of coronavirus infection
- Where
- 3 sites in Russia
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- St. Petersburg Research Institute of Vaccines and Sera
Kidney Failure, Chronic, Covid19
Assessment of Immune Response After Vaccination Against COVID-19 in Patients Treated With Renal Replacement Therapy
Chronically dialyzed patients and kidney transplant recipients have been identified as particularly vulnerable to SARS-CoV-2 infection due to unavoidable exposure.
- Conditions
- Kidney Failure, Chronic, Covid19, Vaccine Reaction, Vaccine Adverse Reaction
- Trial name
- COViNEPH-1 (NCT04905862)
- Testing
- Immune response, Solicited common and expected adverse reactions shortly following vaccination (reactogenicity), use of antipyretic or pain medications and unsolicited adverse events and serious adverse events
- Where
- 4 sites in Poland
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk
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