Clinical trials: Pneumonia; Pulmonary Infection
Pneumonia, Critically Ill
Impact of Rapid Pathogen Detection in ICU Patients With Suspected Pneumonia on Antimicrobial Therapy
The goal of this intervention trial is to determine the feasibility, safety, and potential impact of rapid respiratory pathogen detection by FA Pneumonia Panel on antibiotic therapy in mechanically ventilated critically ill…
- Trial name
- IRISPAT-1 (NCT06478953)
- Testing
- FA Pneumonia Panel
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Covid 19
Attitude of Egyptian Population Toward COVID 19 in Ramadan
During the COVID 19 pandemic and after new cases started to appear in Egypt in march 2020 the Egyptian government issued movement restrictions and placed areas into quarantine to reduce the spread of the virus.
- Trial name
- NCT04401072
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Damanhour University
COVID-19
Predicting COVID-19 Patients' Clinical Outcomes Using ICU Mobility Scale and MRC Sum Score
The investigators hypothesize that early mobility condition and muscle power may be the predictive factors for Coronavirus disease 2019(COVID-19) patients' activity prognosis and hospitalization days.
- Trial name
- NCT05195736
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- Taichung Veterans General Hospital
Ventilator-associated Pneumonia
Risks Factors and Outcome of Recurrences in Patients With Ventilator-Associated Pneumonias (REVAP)
Ventilator-associated pneumonia (VAP) is a frequent and serious complication in the ICU, defined by the development of a lung infection in patients ventilated for more than 48 hours.
- Trial name
- REVAP (NCT06066736)
- Testing
- observational
- Where
- France
- Volunteers
- 1,569 people
- Sponsor
- Société Française d'Anesthésie et de Réanimation
COVID-19
A Study of the Safety and Efficacy of Ciclesonide in the Treatment of Non-hospitalized COVID-19 Patients
The purpose of this study is to assess the safety and efficacy of Alvesco (ciclesonide) Inhalation Aerosol in non hospitalized patients with symptomatic COVID-19 infection in a multicenter, randomized, double-blind, placebo…
- Trial name
- NCT04377711
- Testing
- Ciclesonide
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Covis Pharma S.à.r.l.
COVID-19
Duvelisib to Combat COVID-19
The exceedingly high mortality rates of severe and critical COVID-19 warrant the identification and evaluation of novel therapies that could potentially mitigate the advanced disease manifestations.
- Trial name
- NCT04372602
- Testing
- Duvelisib, Peripheral blood draw
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Washington University School of Medicine
Cross Sectional Hospital Based Study
Risk Perception Associated With Covid-19 Among Anesthetists
Since the outbreak of the COVID-19 pandemic, the anesthesiologists are involved in the riskiest interventions e.g. airway management, endotracheal intubation, and resuscitation.
- Trial name
- NCT04861272
- Testing
- Survey
- Where
- Saudi Arabia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- King Saud University
Covid19
The Prevent Severe COVID-19 (PRESECO) Study
Double-blinded, placebo control, randomized, phase-3 clinical trial to evaluate clinical efficacy of Favipiravir in patients with mild to moderate symptoms related to COVID-19 infection
- Trial name
- PRESECO (NCT04600895)
- Testing
- Favipiravir
- Where
- 38 sites in United States, Brazil and 1 more
- Volunteers
- 1,187 people
- Sponsor
- Appili Therapeutics Inc.
COVID-19, GastroIntestinal Bleeding
Re-EValuating the Inhibition of Stress Erosions (REVISE) - COVID-19 Cohort Study
Commonly employed medications used in critically ill patients requiring life support include proton pump inhibitors (PPIs). These medications are thought to prevent gastrointestinal (GI) bleeding from stress-induced ulceration.
- Trial name
- NCT05715567
- Testing
- Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (NCT03374800)
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- McMaster University
Pregnancy
Prevalence and Impact of COVID-19 Infection in Pregnant Women, Fetuses and Newborns
A novel human coronavirus, named SevereAcute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), emerged in China, in late 2019, and is now spreading quickly causing a pandemic.
- Trial name
- COVIPREG (NCT04355234)
- Testing
- identify SARS-CoV-2 infection by serology, collection of biological samples
- Where
- France
- Volunteers
- 2,446 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19, Left Ventricular Dysfunction
Cardiac Dysfunction in Critically Ill Patients With COVID-19
Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically ill patients infected with COVID-19.
- Conditions
- Covid19, Left Ventricular Dysfunction, Right Ventricular Dysfunction, Pulmonary Hypertension
- Trial name
- CARDYCOVID (NCT04524234)
- Testing
- Echocardiography
- Where
- 5 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Sahlgrenska University Hospital
Procalcitonin, Pneumonia
Procalcitonin Test for Differentiation of the Cause of Pneumonia
The purpose of this study is to evaluate the usefulness of procalcitonin test for differentiation of the cause of pneumonia in patients with cancer.
- Conditions
- Procalcitonin, Pneumonia, Cancer
- Trial name
- NCT03350802
- Testing
- procalcitonin test
- Where
- South Korea
- Volunteers
- 649 people
- Sponsor
- National Cancer Center, Korea
Covid19, Thrombosis Embolism
COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications
Novel coronavirus 2019 (COVID-19) has emerged as a major international public health concern. While much of the morbidity and mortality associated with COVID-19 has been attributed to acute respiratory distress syndrome (ARDS) or…
- Conditions
- Covid19, Thrombosis Embolism, DVT, Pulmonary Embolism
- Trial name
- CORONA-VTE NET (NCT04535128)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 11,000 people
- Sponsor
- Brigham and Women's Hospital
Pneumonia
Safety, Tolerability and Pharmacokinetics of Aerosolized Amikacin in Intubated and Mechanically-ventilated Patients With Nosocomial Pneumonia
This study is to understand how the inhaled form of amikacin is spread throughout the human body and how it is eliminated from the body and to make sure that giving an inhaled form of Amikacin to patients is safe and well…
- Trial name
- NCT01021436
- Testing
- Amikacin inhalation solution (BAY41-6551)
- Where
- 6 sites in United States, France
- Volunteers
- 30 people
- Sponsor
- Bayer
Covid19
COVID-19: Salvage TOcilizumab as a Rescue Measure
Evaluating the efficacy of Tocilizumab in hospitalized patients in the inflammatory phase of COVID-19. Randomization 2:1 (TCZ:standard of care).
- Trial name
- COVIDSTORM (NCT04577534)
- Testing
- iv Tocillizumab (TCZ)
- Where
- Finland
- Volunteers
- 88 people
- Sponsor
- Jarmo Oksi
Long COVID, COVID-19
Group Psychotherapy in Long COVID
The aim of the present study was to establish a single-arm group psychotherapy and to evaluate its clinical effectiveness in long COVID patients.
- Trial name
- NCT06726772
- Testing
- Group Psychotherapy
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Cantonal Hospital of St. Gallen
COVID-19
Effectiveness and Safety of Two Vitamin D3 Supplementation Regimens in Adults with Early-stage COVID-19
This study aimed to determine the effectiveness and safety of individualized vitamin D3 supplementation in adult patients with early-stage severe COVID-19.
- Trial name
- VDCOVID19ACUTE (NCT06585995)
- Testing
- vitamin D (cholecalciferol) supplementation
- Where
- Mexico
- Volunteers
- 216 people
- Sponsor
- Escuela Militar de Graduados de Sanidad, SEDENA
Covid19
Remotely-conducted Trial of Famotidine vs Placebo for Patients at Home With Coronavirus (COVID) of 2019 (COVID-19)
Kit for reading vital signs (thermometer, wrist blood pressure device, finger oximeter) and with study drug is overnighted to qualified subjects with early symptoms of COVID-19.
- Trial name
- Pepcid4COV19 (NCT04565392)
- Testing
- Famotidine 20 milligram tablet
- Where
- United States
- Sponsor
- drpykessupplements.com
COVID-19
Diagnostic Value of Patient - Reported and Clinically Verified Olfactory Disorders (COVID-19)
Participants are healthcare workers and adult outpatients referred in a COVID-19 screening center. Patients-reported symptoms are collected, then participants underwent a simple olfactory test (CODA for Clinical Olfactory…
- Trial name
- COVID-OLFA (NCT04407494)
- Testing
- Reporting of anosmia, ageusia and other clinical symptoms
- Where
- France
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
SARS-CoV, SARS-CoV-2
Study of VXCO-100, a SARS-CoV Candidate Vaccine in Healthy Adults in the United States
The purpose of this study is to evaluate the safety and immunogenicity of ascending dose levels of VXCO-100 in healthy adults.
- Trial name
- NCT05870839
- Testing
- VXCO-100
- Where
- 3 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Vaccine Company, Inc, a wholly owned subsidiary of Eli Lilly and Company
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