Clinical trials: Pneumonia; Pulmonary Infection
Collagen Supplementation, Whey Protein
Effects of Rehabilitation and Supplementation With Hydrolyzed Collagen vs. Whey Protein on the Cardiopulmonary, Renal, Muscular, and Immunohematological Response of COPD Patients
Chronic obstructive pulmonary disease (COPD) induces a severe loss of muscle strength and mass, in addition to reflecting significant pulmonary changes and causing cardiovascular, immunohematological, and renal alterations.
- Conditions
- Collagen Supplementation, Whey Protein, Pulmonary Rehabilitation, COPD - Chronic Obstructive Pulmonary Disease
- Trial name
- NCT07011225
- Testing
- Verisol Collagen 2,5 g/day, Peptech Collagen 2,5 g/day, Peptech Collagen 10 g/day
- Where
- Brazil
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Covid19
Use of Inhaled High-molecular Weight Hyaluronan in Patients With Severe COVID19: Feasibility and Outcomes
To determine whether inhaled Yabro protects against progression of COVID19-induced respiratory failure preventing the passage to non-invasive ventilation (NIV) and promotes recovery from COVID19 lung disease in hospitalized…
- Trial name
- HA-COVID (NCT04830020)
- Testing
- HMW-HA
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
COVID-19
Provide Pre-approval Single-patient Expanded Access (Compassionate Use) of VYD222 for Patients With Symptomatic COVID-19 Refractory to Other Treatments
Provide pre-approval single-patient Expanded Access (Compassionate Use) of VYD222 for patients with symptomatic COVID-19 refractory to other treatments.
- Trial name
- NCT06004128
- Testing
- VYD222
- Sponsor
- Invivyd, Inc.
Pneumonia, Invasive Mechanical Ventilation
Ultrasound Evaluation of Respiratory Muscles During Mechanical Ventilation Weaning in ICU Patients
Patients with pneumonia who require invasive mechanical ventilation in the intensive care unit (ICU) often experience difficulties during the process of being separated from the breathing machine (weaning).
- Conditions
- Pneumonia, Invasive Mechanical Ventilation, Weaning From Mechanical Ventilation in Care Unit, Respiratory Muscle Dysfunction
- Trial name
- NCT07405567
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa Sevket Yilmaz Training and Research Hospital
Covid19
Artificial Intelligence - SARS-CoV-2 (COVID-19) Risk Evaluation
The management of COVID-19 patients in overwhelmed hospital facing the pandemic is a clinical challenge. The improvement of decision making may allow a better allocation of available resources and a better treatment of patients…
- Trial name
- AI-SCoRE (NCT04834934)
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Covid19, Stress, Psychological
Psychological Impact of COVID-19 Pandemic in Healthcare Workers
Background. The current coronavirus disease (COVID-19) has a great impact worldwide. Healthcare workers play an essential role and are one of the most exposed groups.Information about the psychosocial impact on healthcare workers…
- Conditions
- Covid19, Stress, Psychological, Work Related Stress, Epidemic Disease
- Trial name
- PSIMCOV (NCT04506515)
- Testing
- Psychological stress and adaptation at work score (PSAS)
- Where
- Spain
- Volunteers
- 3,000 people
- Sponsor
- Hospital General Universitario de Valencia
Community-Acquired Pneumonia (CAP), Pneumonia
PromotIng Optimal Treatment for Community-acquired PNeumonia in EmErgency Rooms
In North America, up to 5% of preschoolers develop community-acquired pneumonia (CAP) every year. Pneumonia is the second-leading reason for paediatric hospitalization in both Canada and the US; approximately 20% of children…
- Trial name
- PIONEERS (NCT07099976)
- Testing
- The novel care pathway intervention, Usual Care Alone
- Where
- 6 sites in Canada
- Volunteers
- 698 people
- Sponsor
- Jeffrey Pernica
Pneumonia, Influenza, Human
The Effect of Live Attenuated Inactivated Influenza Vaccine on Experimental Human Pneumococcal Carriage Study
The investigators are interested in examining the effect of the Live Attenuated Influenza (flu) Vaccine (LAIV) upon nasal carriage of bacteria called Streptococcus pneumoniae (also known as pneumococcus).
- Trial name
- LAIV/EHPC (NCT03502291)
- Testing
- Study one: LAIV + Inoculation, Study two: Inoculation + LAIV
- Where
- United Kingdom
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Covid-19
A Study in Patients With COVID-19 and Respiratory Distress Not Requiring Mechanical Ventilation, to Compare Standard-of-care With Anakinra and Tocilizumab Treatment The Immunomodulation-CoV Assessment (ImmCoVA) Study
The study is designed as a randomized, controlled, multi-center open-label trial to compare standard-of-care (SOC) treatment with SOC + anakinra or SOC + tocilizumab treatment in hospitalized adult subjects who are diagnosed with…
- Trial name
- NCT04412291
- Testing
- Anakinra Prefilled Syringe, Tocilizumab Prefilled Syringe, Standard-of-care treatment
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska University Hospital
SARS-CoV-2 Infection, COVID-19
Effect of COVID-19 Lockdown on Alcohol and Tobacco Use in Two Chilean Universities
This is a longitudinal study of participants from two university communities in Chile. The primary objective is to examine the effect of a regional lockdown on alcohol and tobacco use, using a difference-in-difference analysis to…
- Trial name
- NCT05069090
- Testing
- Lockdown and other social distancing measures
- Where
- 2 sites in Chile
- Volunteers
- 1,038 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Aged
Effects of the Programme Developed for Sedentary Elderly in the COVID-19 Pandemic: Mobile Interventional Study
The purpose of all these applications is the same: people keep distance and isolate themselves from those in risk groups and patients.
- Trial name
- NCT05110560
- Testing
- "Stay at Home Take a Step Program (SHTSP)"
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Hyperglycemia, Covid19
Dipeptidyl Peptidase-4 Inhibitor (DPP4i) for the Control of Hyperglycemia in Patients With COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a world health issue during the last months, affecting mostly countries with a high metabolic risk, like Mexico.
- Trial name
- Covid19DPP4i (NCT04542213)
- Testing
- Linagliptin tablet, Insulin
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Covid19
Evaluation of the Sanitary Safety of a Healthcare Professional Conference Held 9-11 June 2021 in Paris
The COVID-SRLF study will evaluate the sanitary safety of the French Intensive Care Society (FICS) annual meeting held in Paris Congress Center from June 9th to June 11th 2021 in the Coronavirus Disease 2019 (COVID-2019) pandemic…
- Trial name
- COVID-FREE (NCT04918160)
- Testing
- Exposure to the FICS annual meeting (June 9-11 2021, Paris Congress Center)
- Where
- France
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- French Society for Intensive Care
Covid19
Neutralizing Antibody Level After COVID-19 Vaccination
1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2. investigate the factors on antibody titer.
- Trial name
- NCT05083026
- Testing
- COVID-19 neutralizing antibody
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Kyungpook National University Hospital
Covid19, Vaccine
Immunogenicity of the ChAdox1 n CoV-19 Vaccine With 12-dose Vial
ChAd0x1 nCoV-19 (AZD 1222) is the main vaccine that is planned to roll-out in Thailand and involve vaccinating people especially in high-risk categories.
- Conditions
- Covid19, Vaccine, Immunogenicity
- Trial name
- NCT04961385
- Testing
- Immunogenicity after first dose of participants who received first dose of ChAdox-1 n COV-19 vaccine
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
COVID-19
A Clinical Study to Evaluate the Efficacy and Safety of SIM0417 Orally Co-Administered With Ritonavir in Symptomatic Adult Participants With Mild to Moderate COVID-19
This Phase Ⅱ/Ⅲ study is to evaluate whether or not there is a difference in time recovery of COVID-19 signs and symptoms through Day 29 between SIM0417/ritonavir and placebo.
- Trial name
- NCT05506176
- Testing
- SIM0417
- Where
- 35 sites in China
- Volunteers
- 1,208 people
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Covid19
Managerial and Environmental Risk for COVID 19 in French Long Term Care Institutions
REMPAR EHPAD study addresses environmental and managerial factors associated with an outbreak of COVID 19 in French Long Term Care Institutions in the spring of 2020.
- Trial name
- REMPAR-EHPAD (NCT04579289)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Rennes University Hospital
Stroke, Acute
Covid-19 Epidemic on Acute Stroke Management
The Covid-19 pandemic is a pandemic of an emerging infectious disease, coronavirus 2019 (Covid-19), caused by the coronavirus SARS-CoV-2.
- Trial name
- Stroke-Covid19 (NCT04370197)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Respiratory Tract Infections
Levamisole and Isoprinosine in the Treatment of COVID19: A Proposed Therapeutic Trial
The use of both levamisole \& Isoprinosine has both synergistic and complementary effect in the treatment of COVID 19 infection
- Trial name
- NCT04383717
- Testing
- Levamisole and isoprinosine, Azithromycin and hydroxychloroquine
- Volunteers
- 60 people
- Sponsor
- Cairo University
Long Covid, Depression
Development of an Accessible Cognitive Behavioral Therapy Digital Therapeutic for Individuals With Long COVID
This study will evaluate Toivoa-004 as an experimental digital therapeutic for persons with Long COVID suffering from anxiety or depression.
- Conditions
- Long Covid, Depression, Anxiety
- Trial name
- NCT07714889
- Testing
- Rauha® Digital Therapeutic Platform (Toivoa-004)
- Sponsor
- Toivoa Inc
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